Protein Alignment Tsp2A and UPK1B

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_008883.2
• Gene: UPK1B / 7348
• HGNCID: 12578
• Length: 260
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 50/238 - (21%)
• Similarity: 93/238 - (39%)
• Gaps: 63/238 - (26%)

  Fly    16 IGCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQ-------SFYIGVYVLIGIS 73
            :.|.:..|...|::......||.|..::..::.  :....:|||.       :.:||::|  ||.
Human     8 VRCFQGLLIFGNVIIGCCGIALTAECIFFVSDQ--HSLYPLLEATDNDDIYGAAWIGIFV--GIC 68

  Fly    74 IVMMAV-SFLGCLSALMENTLALFV--FVGTQVFGF-IAIVAGSAVLLQFSTINSSLQPLLNVSL 134
            :..::| ..:|.:.:..:..||.|:  |:   |:.| :|....:|....|.|.|..|:.:|....
Human    69 LFCLSVLGIVGIMKSSRKILLAYFILMFI---VYAFEVASCITAATQQDFFTPNLFLKQMLERYQ 130

  Fly   135 RGFVATSEYTYSNYVLT------MIQENIGCCGATGPWDYL------------------------ 169
            ......::..:.|..:|      |:|:|  |||..||.|:.
Human   131 NNSPPNNDDQWKNNGVTKTWDRLMLQDN--CCGVNGPSDWQKYTSAFRTENNDADYPWPRQCCVM 193

  Fly   170 -DLRQPLP-SSCRDTVSGNAFFNGCVDELT-----------WF 199
             :|::||. .:|:..|.|.....||.:.::           ||
Human   194 NNLKEPLNLEACKLGVPGFYHNQGCYELISGPMNRHAWGVAWF 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	49/235 (21%)
UPK1B	NP_008883.2	Tetraspanin	14..>161	CDD:459767	34/155 (22%)
		uroplakin_I_like_LEL	118..230	CDD:239409	22/113 (19%)