Protein Alignment Tsp2A and TSPAN4

DIOPT Version :9

• Sequence 1: NP_001188523.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: XP_011518638.1
• Gene: TSPAN4 / 7106
• HGNCID: 11859
• Length: 269
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 59/236 - (25%)
• Similarity: 89/236 - (37%)
• Gaps: 45/236 - (19%)

  Fly    20 KYTLFCFNIVAWMISTALFALTVWLRAEPG----FNDWLRILEAQSFYI--GVYVLIGISIVMMA 78
            ::.|..|...|.:....:..:.:||.|..|    .:.....|.|.:..|  |.:|        ||
Human    41 EHRLVSFLWPAQLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFV--------MA 97

  Fly    79 VSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFST--INSSLQPLLNVSLRGFVATS 141
            :.|:|||.|:.||...|..|....:..|: :.|..|:|....|  |:...|..|...|..:
Human    98 IGFVGCLGAIKENKCLLLTFFLLLLLVFL-LEATIAILFFAYTDKIDRYAQQDLKKGLHLY---- 157

  Fly   142 EYTYSNYVLT----MIQENIGCCGATGPWDYLDL----RQP------LPSSCRDTVSGNAFFNGC 192
             .|..|..||    :||.:..|||.:...|:.::    |.|      ...||.....|..:...|
Human   158 -GTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCGLHAPGTWWKAPC 221

  Fly   193 VDEL-TWFFE-----GKTGWIVALAMTLGL---LNVICAVM 224
            .:.: .|..|     |..|...||...|||   :.:.|.|:
Human   222 YETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVV 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_001188523.1	Tetraspannin	18..232	CDD:278750	59/236 (25%)
		tetraspanin_LEL	116..204	CDD:239401	25/109 (23%)
TSPAN4	XP_011518638.1	Tetraspannin	63..261	CDD:278750	55/211 (26%)
		NET-5_like_LEL	136..233	CDD:239418	23/101 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810