Protein Alignment Tsp2A and TSPAN6

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 52/244 - (21%)
• Similarity: 101/244 - (41%)
• Gaps: 29/244 - (11%)

  Fly    11 QLEKQIGCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGVYVLIGISIV 75
            |.:..|.|.|..|..:..:.|:....|.|:.:|  .:....::..:|..::..: .:|||....|
Human     9 QTKPVITCFKSVLLIYTFIFWITGVILLAVGIW--GKVSLENYFSLLNEKATNV-PFVLIATGTV 70

  Fly    76 MMAVSFLGCL-----SALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLR 135
            ::.:...||.     ||.|....|:|:   |.|| .:.:||.....:....|.:|.:.....:|:
Human    71 IILLGTFGCFATCRASAWMLKLYAMFL---TLVF-LVELVAAIVGFVFRHEIKNSFKNNYEKALK 131

  Fly   136 GFVATSEYTYSNYVLTMIQENIGCCGATGPWDYLDL----RQPLPSSC---------RDTVSGNA 187
            .:.:|.:  |.::.:..||..:.|||.|...|:.|.    .:..|.||         ||....|.
Human   132 QYNSTGD--YRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVNN 194

  Fly   188 FFNGCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSFVLVQAVKKEE 236
              .||..::....|.:.|.:..::..:....:|...:::.|.:|:...:
Human   195 --EGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQ 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	48/228 (21%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	48/228 (21%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	22/100 (22%)