DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp2A and Tspan11

DIOPT Version :9

Sequence 1:NP_001188523.1 Gene:Tsp2A / 31080 FlyBaseID:FBgn0024361 Length:244 Species:Drosophila melanogaster
Sequence 2:NP_081019.1 Gene:Tspan11 / 68498 MGIID:1915748 Length:253 Species:Mus musculus


Alignment Length:251 Identity:63/251 - (25%)
Similarity:102/251 - (40%) Gaps:53/251 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 EQLEKQIGCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGVYVLIGISI 74
            ||.:..:..:||.||.||...|:...|:.|:.:|...|.  :.:|.||.:.:|....|:||.:..
Mouse     7 EQDDWLLAHLKYLLFIFNFFFWVGGAAVMAVGIWTLVEK--SGYLSILASSTFAASAYILIFVGG 69

  Fly    75 VMMAVSFLG----------CLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPL 129
            ::|...|||          |||...  .|.|.:|:       :.:|||....:.:..::..|:..
Mouse    70 LVMTTGFLGFGAIIREQKSCLSTYF--CLLLVIFL-------VELVAGVLAHVYYQRLSDELKWH 125

  Fly   130 LNVSLR---GFVATSEYTYSNYVLTMIQENIGCCGATGPWDYLD---------LRQPLPSSCRDT 182
            ||.:|.   |....:|.|.|   :..:|::..|||:....|:..         |.:.:|.||..|
Mouse   126 LNSTLTEHYGQPRAAEITAS---VDRLQQDFKCCGSNSSADWQHSAYILSQEALGRQVPDSCCKT 187

  Fly   183 V---------SGNAF--FNGCVDELTWF------FEGKTGWIVALAMTLGLLNVIC 221
            |         ..|.:  ..||:.:|..|      ..|..|..||.....|::...|
Mouse   188 VVARCGQRAHPSNIYKVEGGCMAKLEQFVADHLLLMGAVGIGVACLQICGMVLTCC 243

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp2ANP_001188523.1 Tetraspannin 18..232 CDD:278750 61/243 (25%)
tetraspanin_LEL 116..204 CDD:239401 25/116 (22%)
Tspan11NP_081019.1 Tetraspannin 16..244 CDD:395265 61/242 (25%)
CD151_like_LEL 112..220 CDD:239408 24/110 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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