Protein Alignment Tsp2A and tspan33b

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: XP_005159085.1
• Gene: tspan33b / 567512
• ZFINID: ZDB-GENE-060503-607
• Length: 266
• Species: Danio rerio
• Alignment Length: 253
• Identity: 60/253 - (23%)
• Similarity: 102/253 - (40%)
• Gaps: 47/253 - (18%)

  Fly    19 VKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIG-VYVLIGISIVMMAVSFL 82
            ::|.||.|:.:.|:.|..:.|:.|:.:|:.. .|.:|    .||.|. ..:||.:.:||..::|.
Zfish    20 IRYFLFFFSFLFWVFSLLIVAIGVYAKAQKA-TDTVR----DSFLIDPAVILIVVGVVMFFITFC 79

  Fly    83 GCLSALMEN--TLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLRGFVATSEYTY 145
            ||:.||.||  .|.:|.|..|.||    :...:..:|.|.....:...|.....:..|...:...
Zfish    80 GCIGALRENIRLLKIFSFSLTLVF----LTQMAIAILGFFYSEQTRDALGEFVKKAIVHYRDDLD 140

  Fly   146 SNYVLTMIQENIGCCGATGPWDY-------------LDLRQPLPSSC-----RDTV--------- 183
            ...::..||:...|||.|...|:             .:.|..:|.||     |:||
Zfish   141 LQNLMDYIQKEFKCCGWTNYTDWSWNPYFNCSSSNPSNERCSVPFSCCTPLPRETVINSMCGFGI 205

  Fly   184 --------SGNAFFNGCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSFVLVQAVK 233
                    :.:.:..||.|....:.|.......||.:.|.|..:...|:|.:|:..::
Zfish   206 QTQNHLNATKSIYSVGCADRAVIWIESHLLLFGALTLGLALPQIAGIVLSQILISEIR 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	60/248 (24%)
tspan33b	XP_005159085.1	Tetraspanin	36..>156	CDD:459767	32/128 (25%)
		penumbra_like_LEL	114..234	CDD:239411	21/119 (18%)