Protein Alignment Tsp2A and tspan14

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001007871.1
• Gene: tspan14 / 493257
• XenbaseID: XB-GENE-868280
• Length: 270
• Species: Xenopus tropicalis
• Alignment Length: 272
• Identity: 63/272 - (23%)
• Similarity: 108/272 - (39%)
• Gaps: 62/272 - (22%)

  Fly    18 CVKYTLFCFNIVAWMISTALFALTVWLRAEPG-FNDWLRILEAQSFYIGVYVLIGISIVMMAVSF 81
            |.||.||.:||:.|:....|..:.:|..:|.| .:|..::.....| ..|::::.:.::|..:.|
 Frog    14 CYKYLLFSYNIIFWLSGMVLLGVGLWAWSEKGILSDITKVTRLHGF-DPVWLVLVVGVIMFTLGF 77

  Fly    82 LGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLRGFVATSEYTYS 146
            .||:.||.||...|..|.|..|..|...:|.:.:...|       |..:....:.|...:..:|.
 Frog    78 AGCVGALRENICLLKFFCGAIVLIFFMELAVAVLAFLF-------QDWVKDRAKDFFENNIKSYR 135

  Fly   147 NYV-----LTMIQENIGCCGATGP--WD---YLDL--------RQPLPSSC-----RDTV----- 183
            :.:     :..:|:...||||..|  ||   |.:.        |..:|.||     ..||
 Frog   136 DDIDLQNLIDSLQKANQCCGAVSPDDWDLNEYFNCSVENPSRERCGVPFSCCVPDPAQTVVNTQC 200

  Fly   184 ------------SGNAFFNGCVDEL-TWFFEGKTGWIVA-LAMTLGLLNVICAVMSFVL---VQA 231
                        ....|..||:..| .|.  .:..:||| :.:.:.:|.:....::..|   ::|
 Frog   201 GYDARRKKPNERPNTTFSKGCISALEAWL--PRNIYIVAGVFLVISILQIFGIYLARTLMSDIEA 263

  Fly   232 VKKEEEQASNYR 243
            ||      :.||
 Frog   264 VK------AGYR 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	57/256 (22%)
tspan14	NP_001007871.1	Tetraspanin	16..257	CDD:459767	56/250 (22%)
		TM4SF9_like_LEL	113..233	CDD:239412	24/128 (19%)