Protein Alignment Tsp2A and tspan18b

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001002439.2
• Gene: tspan18b / 436712
• ZFINID: ZDB-GENE-040718-137
• Length: 258
• Species: Danio rerio
• Alignment Length: 266
• Identity: 61/266 - (22%)
• Similarity: 113/266 - (42%)
• Gaps: 44/266 - (16%)

  Fly     1 MGIG-YGASDEQLEKQ-IGCVKYTLFCFNIVAWMISTALFALTVWLRAEP-GFNDWLRILEAQS- 61
            ||:| ..|....:|.. :.|:||.:|.||.:.::..:.|..:.||:..:| ||.:   |:.|..
Zfish     1 MGLGEASARGTSMEGDCLSCIKYLMFVFNFLIFLGGSFLLGVGVWVVVDPTGFRE---IVAANPL 62

  Fly    62 FYIGVYVLIGISIVMMAVSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSL 126
            .:.|||:::.:..::..:.||||..|:.||...|..|....:..|:|.:|  |.:|.|.......
Zfish    63 LFTGVYIILAMGGMLFLLGFLGCCGAIRENKCLLLFFFMLILIIFLAELA--AAILAFIFREHLT 125

  Fly   127 QPLLNVSLR----GFVATSEYTYSNYVLTMIQENIGCCGATGPWDY-------LDLRQPLPSSC- 179
            :......|:    |:..|..:|.:   ...|.....|||...|.|:       ::..:.:|.:|
Zfish   126 REYFTKELKKHYQGYNNTDVFTST---WNAIMNTFDCCGVNSPEDFEESIFRIINPSEMVPEACC 187

  Fly   180 --------------RDTVSGNAFF---NGCVDELTWFFE---GKTGWIVALAMTLGLLNVICAVM 224
                          .:.:||:..:   .||...:..:||   ...|.:..:.:|:.|..::.|:.
Zfish   188 RRNNHVGESGFSNREECLSGSMLYRNNKGCYSAVVDYFEMYIYVAGALAIVVLTIELFAMVFAMC 252

  Fly   225 SFVLVQ 230
            .|..:|
Zfish   253 LFRGIQ 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	54/244 (22%)
tspan18b	NP_001002439.2	Tetraspanin	21..255	CDD:459767	53/241 (22%)
		uroplakin_I_like_LEL	118..229	CDD:239409	19/113 (17%)