Protein Alignment Tsp2A and tspan7

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_989350.1
• Gene: tspan7 / 394976
• XenbaseID: XB-GENE-941774
• Length: 249
• Species: Xenopus tropicalis
• Alignment Length: 267
• Identity: 63/267 - (23%)
• Similarity: 93/267 - (34%)
• Gaps: 92/267 - (34%)

  Fly    16 IGCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGVYVLIGISIVMMAVS 80
            |.|:|..|..::.|.|:....|.|:.||                ....:|.|:
 Frog    12 ITCLKTLLIIYSFVFWITGVILLAVGVW----------------GKLTLGTYI------------ 48

  Fly    81 FLGCLSALMEN-TLALFVFVGT-------QVFGFIAIVAGSAVLLQFSTINSSLQPL--LNVSLR 135
                 |.:.|| |.|.:|.:||       .:||..|...||..:|:...:..||..|  |...:.
 Frog    49 -----SLIAENSTNAPYVLIGTGTTIIVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELIAGIS 108

  Fly   136 GFVATSEY------TYS----NY--------VLTMIQENIGCCGATGPWDYLDLRQPL------- 175
            |||...|.      ||:    ||        .:..:|.::.|||..   .|.:....|
 Frog   109 GFVFRHEIKDTFLRTYTEAIQNYNGNDERSQAVDDVQRSLRCCGVQ---YYTNWTTSLYWHDHGF 170

  Fly   176 PSSCRDTVSG-------NAFFN-------GCVDELTWFFEGKTGWI------VALAMTLGLLNVI 220
            ||||....|.       |...|       ||.:.:|.|.|...|.|      :|.:..:|:| :.
 Frog   171 PSSCCANTSDCNPQDLRNMTINFTKVNQRGCYELVTSFMETNMGIIAGVAFGIAFSQLIGML-LA 234

  Fly   221 CAVMSFV 227
            |.:..|:
 Frog   235 CCLSRFI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	61/264 (23%)
tspan7	NP_989350.1	Tetraspanin	15..239	CDD:459767	60/260 (23%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	25/105 (24%)