Protein Alignment Tsp2A and Tspan7

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001385666.1
• Gene: Tspan7 / 363447
• RGDID: 1589725
• Length: 249
• Species: Rattus norvegicus
• Alignment Length: 266
• Identity: 62/266 - (23%)
• Similarity: 96/266 - (36%)
• Gaps: 90/266 - (33%)

  Fly    16 IGCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGVYVLIGISIVMMAVS 80
            |.|:|..|..::.|.|:....|.|:.||                ....:|.|:
  Rat    12 ITCLKTLLIIYSFVFWITGAILLAVGVW----------------GKLTLGTYI------------ 48

  Fly    81 FLGCLSALMEN-TLALFVFVGT-------QVFGFIAIVAGSAVLLQFSTINSSLQPL--LNVSLR 135
                 |.:.|| |.|.:|.:||       .:||..|...||..:|:...:..||..|  |...:.
  Rat    49 -----SLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGIS 108

  Fly   136 GFVATSEY------TYS----NY--------VLTMIQENIGCCG-------ATGPWDYLDLRQPL 175
            |||...|.      ||:    ||        .:..:|.::.|||       ::.|: :|:...|
  Rat   109 GFVFRHEIKDTFLRTYTDAMQNYNGKDERSRAVDHVQRSLSCCGVQNYTNWSSSPY-FLEHGIP- 171

  Fly   176 PSSCRDTVSGNAF-------------FNGCVDELTWFFEGKTGWI------VALAMTLGLLNVIC 221
            ||.|.:....|..             ..||.|.:|.|.|...|.|      :|.:..:|:| :.|
  Rat   172 PSCCMNETDCNPLDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGML-LAC 235

  Fly   222 AVMSFV 227
            .:..|:
  Rat   236 CLSRFI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	60/263 (23%)
Tspan7	NP_001385666.1	Tetraspanin	15..239	CDD:459767	59/259 (23%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	24/104 (23%)