Protein Alignment Tsp2A and Tspan1

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001004236.1
• Gene: Tspan1 / 298436
• RGDID: 1303308
• Length: 241
• Species: Rattus norvegicus
• Alignment Length: 240
• Identity: 53/240 - (22%)
• Similarity: 88/240 - (36%)
• Gaps: 40/240 - (16%)

  Fly    19 VKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEA---------QSFYIGVYVLIGISI 74
            :|..:..||::.::...||.|:.:|:..     |....|:|         |...:| |.||....
  Rat     7 IKVMMILFNLLIFLCGAALLAVGIWVSV-----DGTSFLKAFGSLSSSAMQFVNVG-YFLIAAGA 65

  Fly    75 VMMAVSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLRGFVA 139
            |:..:.||||..|..||...|.:|....:..|||.:||:.|.|.::|:.......|.|.    ..
  Rat    66 VLFILGFLGCYGAHSENKCVLMMFFSILLIIFIAEIAGAVVALVYTTMAEQFLTFLVVP----AI 126

  Fly   140 TSEYTYS---NYVLTMIQENIGCCGATGPWDYLDLR-----QPLP-------------SSCRDTV 183
            ..:|.|.   ..|.....|.:.|||.....|:...|     :..|             ..|.:..
  Rat   127 EKDYGYQTEFTQVWNSTMEGLHCCGFNNYTDFNSSRFVKENKVFPPFCCANNTDSHTVEPCTEDK 191

  Fly   184 SGNAFFNGCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSFVL 228
            :.:....||..::..........:..:|:.:..|.:...|:|..|
  Rat   192 AKSMNVQGCFKQILQKIRTNAVTVGGVAVGVAALELAAMVVSMYL 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	53/240 (22%)
Tspan1	NP_001004236.1	Tetraspanin	7..>151	CDD:459767	40/153 (26%)
		uroplakin_I_like_LEL	106..211	CDD:239409	18/108 (17%)