Protein Alignment Tsp2A and Cd37

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: XP_017444339.1
• Gene: Cd37 / 29185
• RGDID: 62035
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 302
• Identity: 60/302 - (19%)
• Similarity: 97/302 - (32%)
• Gaps: 100/302 - (33%)

  Fly   245 PSFDSST---------YRVGHTLAQNLCALEMKTEIGAIADFDEVMVADKEMLINYVEEAMKPDE 300
            ||..|::         :|||             .:||. .:|.|:.:........||...::|.:
  Rat    28 PSSSSASSGVLMVGPNFRVG-------------KKIGC-GNFGELKLGKNLYTNEYVAIKLEPVK 78

  Fly   301 VGALSFSHLLVKFEPKISTMD-----FH----GVVKPVFLDRNGPP--------------KTIFN 342
            ..|... ||..:|...:.:.|     |:    |....:.|:..||.              ||:.
  Rat    79 SRAPQL-HLEYRFYKTLGSADGLPQVFYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVL- 141

  Fly   343 SSAVDII----VTHS---IRRFIGNETTI--RANGSLLHYRH-------NSYTDPAKEVQKPYSL 391
            ..|:.:|    ..||   |.|.:..|..:  |......|..|       ..|.||..:...||..
  Rat   142 MIAIQLISRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHIIHIIDFGLAKEYIDPETKKHIPYRE 206

  Fly   392 FTSYP--------NLHIKRIQ------KTLRKVF-----GSSIPPYNSTYLHVLNQCITKIVGEG 437
            ..|..        |.|:.:.|      :.|..:|     ||.  |:.......|.:...|| |:.
  Rat   207 HKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSL--PWQGLKADTLKERYQKI-GDT 268

  Fly   438 KCRSTVE-YCKQWMEPLTDWV-------------YDTTEGIF 465
            |..:.:| .|:.:.|.:..::             ||....:|
  Rat   269 KRNTPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRNLF 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767
Cd37	XP_017444339.1	Tetraspanin	49..>177	CDD:459767	27/130 (21%)
		CD37_CD82_like_LEL	131..266	CDD:239413	29/138 (21%)