Protein Alignment Tsp2A and Tspan12

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_766595.1
• Gene: Tspan12 / 269831
• MGIID: 1889818
• Length: 305
• Species: Mus musculus
• Alignment Length: 257
• Identity: 52/257 - (20%)
• Similarity: 105/257 - (40%)
• Gaps: 49/257 - (19%)

  Fly    13 EKQIGCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWL----------RILEA--QSFYIG 65
            |..:.|::..|:..|::.|::|.::.|::.|:|      |:|          |:.||  .:::..
Mouse     4 EDSVKCLRCLLYALNLLFWLMSISVLAVSAWMR------DYLNNVLTLTAETRVEEAVILTYFPV 62

  Fly    66 VY-VLIGISIVMMAVSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSA--------VLLQFST 121
            |: |:|.:...::.|..||....:..|.|.|..:.||.:..|...:|...        |.:|:|.
Mouse    63 VHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGTLLVIFCVELACGVWTYEQEVMVPVQWSD 127

  Fly   122 INSSLQPLLNVSLRGFVATSEYTYSNYVLTMIQENIGCCGATGPWDYLDLRQ---PLPSSCRDTV 183
            :.:....:.|..|      ..|.:..:.....|....|||.....|:|::.:   |..|.|....
Mouse   128 MVTLKARMTNYGL------PRYRWLTHAWNYFQREFKCCGVVYFTDWLEMTEMDWPPDSCCVREF 186

  Fly   184 SG-----------NAFFNGCVDELTWFFEGKTGWIVA--LAMTLGLLNVICAVMSFVLVQAV 232
            .|           :.:..||..::..|..|.....|.  |.:::|:..::..:::..|:.|:
Mouse   187 PGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITLLWAL 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	49/247 (20%)
Tspan12	NP_766595.1	Tetraspanin	10..246	CDD:459767	49/247 (20%)
		TM4SF12_like_LEL	116..218	CDD:239410	20/107 (19%)