Protein Alignment Tsp2A and Tspan18

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_899003.1
• Gene: Tspan18 / 241556
• MGIID: 1917186
• Length: 248
• Species: Mus musculus
• Alignment Length: 255
• Identity: 64/255 - (25%)
• Similarity: 104/255 - (40%)
• Gaps: 61/255 - (23%)

  Fly    16 IGCVKYTLFCFNIVAWMISTALFALTVWLRAEP-GFNDWLRILEAQSFY-IGVYVLIGISIVMMA 78
            :.|:||.:|.||...::....|..:.:|:..:| ||.:   |:...... .|.|:::.:..::..
Mouse     6 LSCMKYLMFVFNFFVFLGGACLLGVGIWVLVDPTGFRE---IVATNPLLTTGAYIVLAMGGLLFL 67

  Fly    79 VSFLGCLSALMEN-TLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLRGFVATSE 142
            :.||||..|:.|| .|.||.|:...:   |.:|..||.:|.|.......:......|     |..
Mouse    68 LGFLGCCGAVRENRCLLLFFFLFILI---IFLVELSAAILAFIFREHLTREFFTKEL-----TKH 124

  Fly   143 Y-----------TYSNYVLTMIQENIGCCGATGPWDY----------LDLRQPLPSSC------- 179
            |           |:::.::|     .||||..||.|:          ||..: :|.:|
Mouse   125 YQGDNDTDVFSATWNSVMIT-----FGCCGVNGPEDFKLASVFRLLTLDTEE-VPKACCRREPQT 183

  Fly   180 RDTV---------SGNAFFN--GCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSFVL 228
            ||.|         ..|.|.|  ||...:...||  |...:|.|..:|:|.:...:|.|.:
Mouse   184 RDGVVLSREECQLGRNPFINKQGCYTVILNTFE--TYVYLAGAFAIGVLAIELFLMVFAM 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	63/252 (25%)
Tspan18	NP_899003.1	Tetraspanin	10..245	CDD:459767	63/251 (25%)
		uroplakin_I_like_LEL	105..218	CDD:239409	27/125 (22%)