Protein Alignment Tsp2A and Tspan33

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_666285.1
• Gene: Tspan33 / 232670
• MGIID: 1919012
• Length: 283
• Species: Mus musculus
• Alignment Length: 256
• Identity: 57/256 - (22%)
• Similarity: 105/256 - (41%)
• Gaps: 49/256 - (19%)

  Fly    19 VKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGV---YVLIGISIVMMAVS 80
            |||.||.||::.|:||..:.|:.|:.|.       ::..||....:.|   .:||.:.::|..::
Mouse    22 VKYLLFFFNMLFWVISMVMVAVGVYARL-------MKHAEAALACLAVDPAILLIVVGVLMFLLT 79

  Fly    81 FLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFS-TINSSLQPLLNVSLRGFVATSEYT 144
            |.||:.:|.||...|..|.......|:..:|...:...|| .....:..::|.::..:  ..:..
Mouse    80 FCGCIGSLRENICLLQTFSLCLTIVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHY--RDDLD 142

  Fly   145 YSNYVLTMIQENIGCCGATG--PWD---YLDLRQPLPS--------SC---------RDTVSGNA 187
            ..| ::...|:...|||...  .|.   |.:..:..||        ||         .:|:.|..
Mouse   143 LQN-LIDFGQKKFSCCGGISYRDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPNQAVINTMCGQG 206

  Fly   188 -------------FFNGCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSFVLVQAVKKE 235
                         :.|||:|:|..:.......:..:|:.|.:..::..::|.|||..:|.:
Mouse   207 MQALDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQVLVNQIKDQ 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	55/249 (22%)
Tspan33	NP_666285.1	Tetraspanin	22..262	CDD:459767	55/249 (22%)
		penumbra_like_LEL	116..236	CDD:239411	21/122 (17%)