Protein Alignment Tsp2A and Upk1b

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_849255.2
• Gene: Upk1b / 22268
• MGIID: 98912
• Length: 260
• Species: Mus musculus
• Alignment Length: 241
• Identity: 54/241 - (22%)
• Similarity: 100/241 - (41%)
• Gaps: 63/241 - (26%)

  Fly    13 EKQIGCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQ-------SFYIGVYVLI 70
            :..:.|.:..|...:::..|...||.|..::..::.  :....:|||.       :.:||::|
Mouse     5 DSTVRCFQGLLIFGHVIVGMCGIALTAECIFFVSDQ--HSLYPLLEATNNDDIFGAAWIGMFV-- 65

  Fly    71 GISIVMMAV-SFLGCLSALMENTLALFV--FVGTQVFGF-IAIVAGSAVLLQFSTINSSLQPLLN 131
            ||.:..::| :.:|.:.:..:..||.|:  |:   |:|| :|....:|....|.|.|..|:.:|.
Mouse    66 GICLFCLSVLAIVGIMKSNRKILLAYFIMMFI---VYGFEVASCITAATQRDFFTTNLFLKQMLM 127

  Fly   132 VSLRGFVATSEYTYSNYVLT------MIQENIGCCGATGP--W--------------DY------ 168
            ........|::..:.|..:|      |:|::  |||..||  |              ||
Mouse   128 RYQNNSPPTNDDEWKNNGVTKTWDRLMLQDH--CCGVNGPSDWQKYTSAFRVENNDADYPWPRQC 190

  Fly   169 --LD-LRQPLP-SSCRDTVSGNAFFNGCVDELT-----------WF 199
              :| |::||. .:|:..|.|.....||.:.::           ||
Mouse   191 CVMDKLKEPLNLDACKLGVPGYYHSQGCYELISGPMDRHAWGVAWF 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	53/235 (23%)
Upk1b	NP_849255.2	Tetraspanin	14..>161	CDD:459767	35/155 (23%)
		uroplakin_I_like_LEL	120..230	CDD:239409	24/111 (22%)