Protein Alignment Tsp2A and Tspan7

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_062608.2
• Gene: Tspan7 / 21912
• MGIID: 1298407
• Length: 249
• Species: Mus musculus
• Alignment Length: 266
• Identity: 63/266 - (23%)
• Similarity: 96/266 - (36%)
• Gaps: 90/266 - (33%)

  Fly    16 IGCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGVYVLIGISIVMMAVS 80
            |.|:|..|..::.|.|:....|.|:.||                ....:|.|:
Mouse    12 ITCLKTLLIIYSFVFWITGVILLAVGVW----------------GKLTLGTYI------------ 48

  Fly    81 FLGCLSALMEN-TLALFVFVGT-------QVFGFIAIVAGSAVLLQFSTINSSLQPL--LNVSLR 135
                 |.:.|| |.|.:|.:||       .:||..|...||..:|:...:..||..|  |...:.
Mouse    49 -----SLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGIS 108

  Fly   136 GFVATSEY------TYS----NY--------VLTMIQENIGCCG-------ATGPWDYLDLRQPL 175
            |||...|.      ||:    ||        .:..:|.::.|||       ::.|: :||...|
Mouse   109 GFVFRHEIKDTFLRTYTDAMQNYNGNDERSRAVDHVQRSLSCCGVQNYTNWSSSPY-FLDHGIP- 171

  Fly   176 PSSCRDTVSGNAF-------------FNGCVDELTWFFEGKTGWI------VALAMTLGLLNVIC 221
            ||.|.:....|..             ..||.|.:|.|.|...|.|      :|.:..:|:| :.|
Mouse   172 PSCCMNETDCNPLDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGML-LAC 235

  Fly   222 AVMSFV 227
            .:..|:
Mouse   236 CLSRFI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	61/263 (23%)
Tspan7	NP_062608.2	Tetraspanin	15..239	CDD:459767	60/259 (23%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	25/104 (24%)