Protein Alignment Tsp2A and Tspan10

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_663338.2
• Gene: Tspan10 / 208634
• MGIID: 2384781
• Length: 332
• Species: Mus musculus
• Alignment Length: 279
• Identity: 68/279 - (24%)
• Similarity: 108/279 - (38%)
• Gaps: 62/279 - (22%)

  Fly     7 ASDEQLEKQIGCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDW-LRILEAQSFYIG----- 65
            ||...|.....||||.:|        :|..||:|...|....|.  | |.:..:|....|
Mouse    63 ASSLPLSTGSNCVKYLIF--------LSNFLFSLPSLLALAAGL--WGLTVKRSQGIGWGGPVPT 117

  Fly    66 --VYVLIGISIVMMAVSFLGCLSALMENTLALFVFVGTQVFGF-IAIVAGSAVLLQFSTINSSLQ 127
              :.:|:...:|:..||..|||.|..||:..|..:.|..:|.. :..:||..::..:..:..||:
Mouse   118 DPMLMLVLGGLVVSVVSLSGCLGAFCENSCLLHWYCGAVLFCLALEALAGVLMVTLWKPLQDSLK 182

  Fly   128 PLLNVSLRGFVATSEYTYSNYVLTMIQENIGCCGATGPWD-----YLDLRQP------LPSSC-- 179
            ..|:.::..:....:.   :::|..:|..:.||||....|     |.:...|      ||:||
Mouse   183 YTLHAAIIHYWDDPDL---HFLLDQVQLGLQCCGAVSYQDWQQNLYFNCSSPGVQACSLPASCCI 244

  Fly   180 --------------------RDTVSGN-AFFNGCVDELTWFFEGKTGWI----VALAMTLG--LL 217
                                ...|:|. .|..||...|..:..|.||.|    ||:.|..|  ||
Mouse   245 NPQEDGAVVNTQCGFGALGLDQNVAGQVVFLQGCWPALQEWLRGNTGAIGDCAVAVVMIQGTELL 309

  Fly   218 NVICAVMSFVLVQAVKKEE 236
            ...|.:.:..:.:|.:..|
Mouse   310 LAACLLRALAVHEAAEDIE 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	62/259 (24%)
Tspan10	NP_663338.2	Tetraspanin	75..225	CDD:459767	39/162 (24%)
		oculospanin_like_LEL	171..290	CDD:239420	23/121 (19%)