Protein Alignment Tsp2A and tsp-17

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001129920.2
• Gene: tsp-17 / 192067
• WormBaseID: WBGene00006643
• Length: 312
• Species: Caenorhabditis elegans
• Alignment Length: 311
• Identity: 64/311 - (20%)
• Similarity: 111/311 - (35%)
• Gaps: 99/311 - (31%)

  Fly    17 GCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSF-------YIGVYVLIGISI 74
            ||::..:..|:|..|:.:.....|.:|:..:|..|   .||:...|       ....||.:....
 Worm     9 GCLRVAVSIFSIYYWLSALGHVFLGLWMLLDPKRN---YILDLVHFSENDPLLKASAYVSLVCGC 70

  Fly    75 VMMAVSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLRGFVA 139
            ..:.|.|||...|:..:...|..||...:..|:|.||...:.|.:....|:  ..:.|.|:. :.
 Worm    71 AQLLVGFLGLCGAVNRSRFLLLAFVMFLIGTFLADVAMGTLSLFYKDKFSN--NYMGVYLKN-LT 132

  Fly   140 TSEYTYSNYVLTM----------IQENI-------------------------------GCCGAT 163
            .:.|:...:||.:          ::||:                               .|||:.
 Worm   133 YNRYSRDRWVLPLMDTIQFYVYSVKENVREIVKSKYGVMTSEPENKMVTEFIDKLQFYEKCCGSL 197

  Fly   164 GPWDYL-------------DLRQPL-PSSCRDTVSGNAFFN----------------------GC 192
            ||.||:             ::..|| |.||...::|.:..|                      ||
 Worm   198 GPTDYISSRWSQSTNQDSEEIESPLFPVSCCTQITGASALNPLAKSYARCQQIGANRQWRHAVGC 262

  Fly   193 VDEL-------TWFFEGKTGWIVALAMTLGLLNVICAVMSFVLVQAVKKEE 236
            .:.|       .|.|.| .|:..||.|.||:. :.|.::|.:.:..|.:::
 Worm   263 SERLMSWFNEQIWIFVG-FGFGSALTMMLGIC-LSCCLISKIRIYHVIRDD 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	61/301 (20%)
tsp-17	NP_001129920.2	Tetraspanin	11..>150	CDD:459767	31/144 (22%)
		CD37_CD82_like_LEL	153..275	CDD:239413	19/121 (16%)