Protein Alignment Tsp2A and TSPAN19

DIOPT Version :9

• Sequence 1: NP_001188523.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001094387.1
• Gene: TSPAN19 / 144448
• HGNCID: 31886
• Length: 248
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 46/240 - (19%)
• Similarity: 85/240 - (35%)
• Gaps: 67/240 - (27%)

  Fly    19 VKYTLFCFNIV--AWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGV-----------YVLI 70
            :||.|   |::  |:::...||.         ||..|| :|:..:|....           .:||
Human    10 IKYFL---NLINGAFLVLGLLFM---------GFGAWL-LLDRNNFLTAFDENNHFIVPISQILI 61

  Fly    71 GISIVMMAVSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLR 135
            |:....:....||.:....|....|.|:.....:.|...|..||.::   |....:|.|.:..:
Human    62 GMGSSTVLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFII---TKKEEVQQLWHDKI- 122

  Fly   136 GFVATSEYTYSNY-------------VLTMIQENIGCCGATGPWDYLDLRQ-----PLPSSCR-- 180
                  ::..|.|             :|..:|:.:.|||.....|::..:.     .:|.||.
Human   123 ------DFVISEYGSKDKPEDITKWTILNALQKTLQCCGQHNYTDWIKNKNKENSGQVPCSCTKS 181

  Fly   181 -------DTVSGNAFFNGCVDELT-WFFEGKTGWIVALAMTLGLL 217
                   |......:..||.:::: |:   ....:..:.:..|||
Human   182 TLRKWFCDEPLNATYLEGCENKISAWY---NVNVLTLIGINFGLL 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_001188523.1	Tetraspannin	18..232	CDD:278750	46/240 (19%)
		tetraspanin_LEL	116..204	CDD:239401	18/115 (16%)
TSPAN19	NP_001094387.1	Tetraspannin	9..240	CDD:278750	46/240 (19%)
		CD37_CD82_like_LEL	107..212	CDD:239413	18/117 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810