Protein Alignment Tsp2A and Upk1a

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_081091.1
• Gene: Upk1a / 109637
• MGIID: 98911
• Length: 257
• Species: Mus musculus
• Alignment Length: 266
• Identity: 56/266 - (21%)
• Similarity: 85/266 - (31%)
• Gaps: 101/266 - (37%)

  Fly    27 NIVAWMISTALFALTVWLRAE----------PGFND-----WLRILEAQSFYI----GV------ 66
            ||:..:...||||.|||:.|:          .|.:|     |:.|....||::    ||
Mouse    23 NIIILLSGLALFAETVWVTADQYRVYPLMGVSGKDDVFAGAWIAIFCGFSFFVVASFGVGAALCR 87

  Fly    67 --YVLIGISIVMMAVSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPL 129
              |:::...::|:.|....|.|.:...|..                       .:...|.||
Mouse    88 RRYMILTYLLLMLIVYIFECASCITSYTHR-----------------------DYMVSNPSL--- 126

  Fly   130 LNVSLRGFVATSEYTYSNYVLTMIQENI----GCCGATGPWDYLDLRQPL------------PSS 178
              ::.:.....|..|.....||.:.:.|    .|||.:||.|:::.....            |..
Mouse   127 --ITKQMLTYYSADTDQGQELTRLWDRIMIEQECCGTSGPMDWVNYTSAFRAATPEVVFPWPPLC 189

  Fly   179 CRDTVSGN----------------AFFNGC-------VDELTWFFEGKTGWIVALAMTLGLLNVI 220
            ||.|  ||                .|..||       :|..||    ...|. ..|:.:..|.|:
Mouse   190 CRRT--GNFIPINEDGCRVGHMDYLFTKGCFEHIGHAIDSYTW----GISWF-GFAILMWTLPVM 247

  Fly   221 CAVMSF 226
            ...|.|
Mouse   248 LIAMYF 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	56/266 (21%)
Upk1a	NP_081091.1	Tetraspanin	23..>161	CDD:459767	34/165 (21%)
		uroplakin_I_like_LEL	111..229	CDD:239409	25/147 (17%)