Protein Alignment Tsp2A and TSPAN9

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: XP_047284080.1
• Gene: TSPAN9 / 10867
• HGNCID: 21640
• Length: 330
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 57/242 - (23%)
• Similarity: 102/242 - (42%)
• Gaps: 42/242 - (17%)

  Fly    18 CVKYTLFCFNIVAWMISTALFALTVWLRAEPG----FNDWLRILEAQSFYIGVYVLIGISIVMMA 78
            |:||.:|.||::.|:....|..:.:||....|    |:.....|.|.:      ::|.|..::|.
Human    99 CLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAAN------LVIAIGTIVMV 157

  Fly    79 VSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQF----STINSSLQPLLNVSLRGFVA 139
            ..|||||.|:.||...|..|.   :...:.::|...:|:.|    ..:|.:.:..|...|..:
Human   158 TGFLGCLGAIKENKCLLLSFF---IVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLLY-- 217

  Fly   140 TSEYTYSNYVL----TMIQENIGCCGATGPWDYLDLRQPLPSS------CRDTVSG---NA---- 187
               :|.:|..|    .:||..:.|||.|   ||.|....|..:      |.:...|   ||
Human   218 ---HTENNVGLKNAWNIIQAEMRCCGVT---DYTDWYPVLGENTVPDRCCMENSQGCGRNATTPL 276

  Fly   188 FFNGCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSFVLVQAVKK 234
            :..||.:::..:|:.....:..:.|.:.::.::....|..|.|.:.:
Human   277 WRTGCYEKVKMWFDDNKHVLGTVGMCILIMQILGMAFSMTLFQHIHR 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	55/235 (23%)
TSPAN9	XP_047284080.1	Tetraspanin	100..319	CDD:459767	55/235 (23%)
		NET-5_like_LEL	196..293	CDD:239418	23/104 (22%)