Protein Alignment Tsp2A and TSPAN1

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: XP_011538762.1
• Gene: TSPAN1 / 10103
• HGNCID: 20657
• Length: 258
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 57/224 - (25%)
• Similarity: 94/224 - (41%)
• Gaps: 41/224 - (18%)

  Fly    19 VKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRIL-----EAQSFYIGVYVLIGISIVMMA 78
            :|..:..||::.::...||.|:.:|:..:..  .:|:|.     .|..|....|.||...:|:.|
Human     7 IKTMMILFNLLIFLCGAALLAVGIWVSIDGA--SFLKIFGPLSSSAMQFVNVGYFLIAAGVVVFA 69

  Fly    79 VSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSL--RGFVATS 141
            :.||||..|..|:..||..|....:..|||.||.:.|.|.::|:......||.|..  :.:.:..
Human    70 LGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDYGSQE 134

  Fly   142 EYTYSNYVLTMIQENIGCCGATGPWDYLDLRQPL--------PSSCRDTVSGNA----------- 187
            ::|   .|.....:.:.|||.|...|:.|  .|.        |..|.|.|:..|
Human   135 DFT---QVWNTTMKGLKCCGFTNYTDFED--SPYFKENSAFPPFCCNDNVTNTANETCTKQKAHD 194

  Fly   188 -FFNGCVDELTWFFEGKTGWIVALAMTLG 215
             ...||.::|  .::.:|.     |:|:|
Human   195 QKVEGCFNQL--LYDIRTN-----AVTVG 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	57/224 (25%)
TSPAN1	XP_011538762.1	Tetraspanin	7..>151	CDD:459767	39/148 (26%)
		uroplakin_I_like_LEL	110..212	CDD:239409	22/113 (19%)