Protein Alignment Tsp2A and TSPAN2

DIOPT Version :9

• Sequence 1: NP_001188523.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_005716.2
• Gene: TSPAN2 / 10100
• HGNCID: 20659
• Length: 221
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 59/245 - (24%)
• Similarity: 98/245 - (40%)
• Gaps: 60/245 - (24%)

  Fly    18 CVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQS-----FYIGVYVLIGISIVMM 77
            |:||.|..||::.|:..:|:.|..:|.|    |...::.|.::.     ||:|:|||:|...:||
Human    10 CIKYLLLGFNLLFWLAGSAVIAFGLWFR----FGGAIKELSSEDKSPEYFYVGLYVLVGAGALMM 70

  Fly    78 AVSFLGCLSALMEN--------TLALFVF---VGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLN 131
            ||.|.||..|:.|:        |..|.:|   |.|.||.||.                     ..
Human    71 AVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIG---------------------KG 114

  Fly   132 VSLRGFVATSEYTYSNYV---------LTMIQENIGCCGATGPWDYLDLRQPLPSSCRDTVSGNA 187
            |::|......|..|::|:         |........|||.       :..:.:..:|...:.|:
Human   115 VAIRHVQTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCGK-------ESSEQVQPTCPKELLGH- 171

  Fly   188 FFNGCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSFVLVQAVKKEEE 237
              ..|:||:......|...|..:.:.:..|.:...:.|.||..|::...:
Human   172 --KNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRD 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_001188523.1	Tetraspannin	18..232	CDD:278750	58/238 (24%)
		tetraspanin_LEL	116..204	CDD:239401	14/96 (15%)
TSPAN2	NP_005716.2	Tetraspannin	11..210	CDD:395265	55/233 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1205716at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X522
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820