Protein Alignment Tsp2A and tspan18

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001093673.1
• Gene: tspan18 / 100101661
• XenbaseID: XB-GENE-868385
• Length: 247
• Species: Xenopus tropicalis
• Alignment Length: 255
• Identity: 64/255 - (25%)
• Similarity: 103/255 - (40%)
• Gaps: 62/255 - (24%)

  Fly    16 IGCVKYTLFCFNIVAWMISTALFALTVWLRAEP-GFNDWLRILEAQSFYIGVYVLIGISIVMMAV 79
            :.|:||.:|.||...::....|..|.||:..:| ||.:  .|......::|.|:::.:..::..:
 Frog     6 LSCIKYLMFIFNFFIFLGGATLLGLGVWVFVDPTGFRE--IIATTPLLFMGAYLVLAMGGMLFLL 68

  Fly    80 SFLGCLSALMENTLALFVFVGTQVFGFIAIV---AGSAVLLQFSTINSSLQPLLNVSL-RGFVA- 139
            .||||..|:.||...|..|     |.||.::   ..||.:|.|         |...:| :.|.|
 Frog    69 GFLGCCGAIRENKCLLVFF-----FMFILVIFLAELSAAILAF---------LFRENLSKDFFAR 119

  Fly   140 ----------TSEYTYSNYVLTMIQENIGCCGATGPWDYLDLRQ--------PLPSSC--RDTVS 184
                      ::|...|.:...||  ..||||..||.|:.|..:        |:|.:|  |:..|
 Frog   120 EVKKHYHGDNSTEVFSSTWNSIMI--TFGCCGVNGPEDFNDAHRFRAMHPFAPVPEACCRREVQS 182

  Fly   185 --------------GNAFFN--GCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSFVL 228
                          |..:.|  ||...:....|...  .:|.|:.:|:|.:....|.|.:
 Frog   183 RAGKIVSRAECLTGGENYQNRQGCYSVIVNSVEPYV--YIAGALAIGVLAIELLSMVFAM 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	63/252 (25%)
tspan18	NP_001093673.1	Tetraspanin	9..244	CDD:459767	63/252 (25%)
		uroplakin_I_like_LEL	105..217	CDD:239409	27/122 (22%)