Protein Alignment Tsp2A and tspan15

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001017773.1
• Gene: tspan15 / 100000710
• ZFINID: ZDB-GENE-050417-295
• Length: 296
• Species: Danio rerio
• Alignment Length: 267
• Identity: 59/267 - (22%)
• Similarity: 106/267 - (39%)
• Gaps: 60/267 - (22%)

  Fly    19 VKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGVYVLIGISIVMMAVSFLG 83
            :|::|..:..:.|:|...:.|:.::...|   ....:.||. .|.....:||.:.|:|..|||:|
Zfish    16 LKFSLIGYATIFWLIGGFILAIGIYAEVE---RQRYKTLEG-VFLAPAIILIVLGIIMFIVSFIG 76

  Fly    84 CLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLR-GFVATSEYTYSN 147
            .|::|.:|...|.||:.......:..:.|..|.|.|.  |.::. :||.::| |.|        |
Zfish    77 VLASLRDNLCLLKVFLYMLALCLVLELVGGIVALIFK--NQTVD-ILNKNIRKGMV--------N 130

  Fly   148 Y--------VLTMIQENIGCCGAT--GPWD---YLDLRQPLPSSCR--------------DTVSG 185
            |        ::..:|:...|||.|  ..|:   |.:...|.|.:|.              :|:.|
Zfish   131 YYDDLDFKNIMDFVQKTFKCCGGTEYQDWEVNMYHNCSAPGPLACAAPYTCCIVTPGEVVNTMCG 195

  Fly   186 NAFFN-------------GCVDEL-TWFFEG-KTGWIVALAMTLGLLNVICAVMSFVLVQAVKKE 235
            ....|             ||.|.: .|..:. ||  :..|.:.:.|......:.:::.:..|:..
Zfish   196 YKTLNKDRHENTDVIYIRGCTDAVFIWLIDNYKT--MAGLLLGIFLPQFFGVIFTWLYITRVEDA 258

  Fly   236 EEQASNY 242
            .|:...|
Zfish   259 IEEYGYY 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	56/253 (22%)
tspan15	NP_001017773.1	Tetraspanin	16..>153	CDD:459767	38/151 (25%)
		penumbra_like_LEL	110..227	CDD:239411	27/127 (21%)