DRSC/TRiP Functional Genomics Resources

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Protein Alignment Naa30A and NAA50

DIOPT Version :9

Sequence 1:NP_726727.1 Gene:Naa30A / 31079 FlyBaseID:FBgn0024362 Length:377 Species:Drosophila melanogaster
Sequence 2:NP_079422.1 Gene:NAA50 / 80218 HGNCID:29533 Length:169 Species:Homo sapiens


Alignment Length:135 Identity:36/135 - (26%)
Similarity:61/135 - (45%) Gaps:4/135 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly   238 HQMHDIMRLIQAELSEPYSIYTYRYFIYNWPKLCFLASHDNQYVGAIVCKLDMHMNVRRGYIAML 302
            |.:..:.||.|......|:...|: .:....:|..||..::..|||:.|::|...|.:|.||..|
Human    14 HNIKQLKRLNQVIFPVSYNDKFYK-DVLEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTL 77

  Fly   303 AVRKEYRKLKIGTTLVTKAIEAMLADNA-DEVVLETEMRNQPALRLYENLGF--VRDKRLFRYYL 364
            .....||:|.|||.::...:.....|.. |.:.|..::.|:.|:..|...||  :..|:.:...:
Human    78 GCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEIIETKKNYYKRI 142

  Fly   365 NGVDA 369
            ...||
Human   143 EPADA 147

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Naa30ANP_726727.1 rimI 242..370 CDD:273701 35/131 (27%)
Acetyltransf_1 276..354 CDD:278980 24/80 (30%)
NAA50NP_079422.1 RimI 10..145 CDD:223532 34/131 (26%)
Acetyl-CoA binding. /evidence=ECO:0000269|PubMed:21900231, ECO:0000269|PubMed:27484799, ECO:0000269|Ref.18, ECO:0007744|PDB:2PSW, ECO:0007744|PDB:3TFY, ECO:0007744|PDB:4X5K 77..90 5/12 (42%)
Coenzyme A binding. /evidence=ECO:0000269|PubMed:21900231, ECO:0000269|PubMed:27484799, ECO:0000269|Ref.18, ECO:0007744|PDB:2PSW, ECO:0007744|PDB:3TFY, ECO:0007744|PDB:4X5K 117..126 3/8 (38%)
Substrate binding. /evidence=ECO:0000269|PubMed:21900231, ECO:0000269|PubMed:27484799, ECO:0007744|PDB:3TFY, ECO:0007744|PDB:4X5K 138..141 0/2 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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