Protein Alignment CG11409 and Prg4

DIOPT Version :10

• Sequence 1: NP_569902.2
• Gene: CG11409 / 31078
• FlyBaseID: FBgn0024366
• Length: 1279
• Species: Drosophila melanogaster
• Sequence 2: NP_001099432.4
• Gene: Prg4 / 289104
• RGDID: 1308976
• Length: 1275
• Species: Rattus norvegicus
• Alignment Length: 1196
• Identity: 228/1196 - (19%)
• Similarity: 344/1196 - (28%)
• Gaps: 421/1196 - (35%)

  Fly   191 HPPAPPPVVYQDFKPVTAASQPSANPAAAPSAARFSSHYSAKNAQFLR-----------KPKPSE 244
            |.|..||       |.||...|.|:.....:..|.......|..:.:.           :.:.|.
  Rat   108 HNPTSPP-------PKTAPPPPGASRTIKSTTKRSPKSPKKKTKKVVESEEITEEHSVSENQESS 165

  Fly   245 GGGGSLSSTVKPVADI-------LESLGIVSGGKSDSAHKRYALDDYYPAESAPQPSVVAVADLR 302
            ....|.|||::.:...       |:....|...|.::..|:          ..|:|.||
  Rat   166 SSSSSSSSTIRKIKSSKNSANRELQKNPKVKDNKKNTPKKK----------PNPEPPVV------ 214

  Fly   303 GLHGARIRPEAYSNFKPLNIGEELRVKPEVEGYLTRFGIVRKAPKALKKEAKPTEEPTGAHTELS 367
                    .||.|.   |:.||                     ||     ..|..:|...|.:::
  Rat   215 --------DEAGSG---LDNGE---------------------PK-----LTPPPDPPTPHNKVT 242

  Fly   368 TA---TARLPPTGNAELAKLLENLQELERLQSQPKRKTPK-STTTSTTTTTTSTTTTTTPAPVPL 428
            .:   ||..|.|....||               |..:|.| :::||...||..|..||
  Rat   243 ASPKTTAAKPVTPKPSLA---------------PNSETSKEASSTSNKETTVETKETT------- 285

  Fly   429 ITHGEPLLIEAKKPRRRIDPNIDINFANGGNQQATPTGSDELSKLLQNLQELEKLKINPENVIKA 493
                     |..|.            ::...::.|.:..:..|....:.:::|.....|:|
  Rat   286 ---------ETNKQ------------SSASKKEKTTSAKETRSAENTSAKDVEPTSTTPKN---- 325

  Fly   494 ASPGVQSLSSRFSTTSTSTSTTT-----TTTTTPSPSQNEARELQRILKQLQQLDQSSRTTTSTT 553
            ::|          ||:....|||     |||..|.|:..|.........:|....:.:.||....
  Rat   326 SAP----------TTTKKPVTTTKEPVPTTTKGPEPTSKEPAPTTPKEPELTIPKEPAPTTKKPA 380

  Fly   554 STTAKPLRNQALGLGVGQGNSLGAADLLQLQRLLSDDRELEKLYEQARNSKKKQHPKTTSSTTST 618
            .||.|                                       |.|..:.|:..|.|...:..|
  Rat   381 PTTPK---------------------------------------EPAPTTPKEPEPTTPKESAPT 406

  Fly   619 T------STTTTPRPTPSVDHAQFEALITRVQQLEQLQQPTTQPNFLTRNVAGSRPVISLPSNDY 677
            |      :|...|.||...:.|                 |||.          ..|..:.|
  Rat   407 TPKEPAPTTPKEPAPTTPKEPA-----------------PTTP----------KEPAPTTP---- 440

  Fly   678 AHLQELSPTSASLLPGGGTVEISTAASTTKQ-RPLSQFERTNGLLREEVHPQDYVQLQKLLSKVQ 741
               :|.:||:....|   |.....|.:|.|: .|.:..|......:|   |......:...:..:
  Rat   441 ---KEPAPTTKKPEP---TTPKEPAPTTPKEPAPTTPKEPAPNTPKE---PAPTTPKEPAPTTPK 496

  Fly   742 ELERVQLRTEHVTHPHSQLVTAASIRSPNVKTVNGAHIVYAQPARDQVVELEPELKLDLPVYEKP 806
            |.|....:....|.|.....|.....:|...         .:||  .....||     .|...|.
  Rat   497 EPESTTPKEPAPTTPKEPAPTTPKEPAPTTP---------KEPA--PTTPKEP-----APTTPKE 545

  Fly   807 VTMATPSQSSSEELRELAMSQPAHPQRGSSADFGQFQQFFGSLEDTGERQSYQHMQPIYKTVQNQ 871
            ....||.:.:....:|.|.:.|..|...:..                |..|....:|...|.:..
  Rat   546 PAPTTPKEPAPTTPKEPAPTTPKEPVPTTPK----------------EPASTTPKEPAPTTPKEP 594

  Fly   872 PPTTPAAPR-FVPARRAPTTPSSGPRKGDLEELQKLLYNTQQLQKLGVALPHELSQQLESQLQAT 935
            .||||..|. ..|...|||||                      ::.....|.|.:.....:...|
  Rat   595 APTTPKEPAPTTPKEPAPTTP----------------------KEPAPTTPKEPALTTPKEPAPT 637

  Fly   936 SSSTSSTT----TTTTSTTPAPAQVHDTSSPAVFSLTTSRPRV----RPIP----EAKPTTESSL 988
            ......||    ..||...|||      ::|...:.||.:|.:    .|:|    |..|||...
  Rat   638 PKEPEPTTPKEPAPTTPKEPAP------TTPKEPAPTTKKPELTIPKEPVPTTPKEPAPTTPKE- 695

  Fly   989 QLPVFSATKIIEAAIKRAANRIGVSTELAPKQGLPSELAKGLGVGSGFRRRSDEGDAEDLNEGDE 1053
              |..:.||..|.:..:.      .|...||:..|: |.|             |.:.....|.:.
  Rat   696 --PAPTTTKKPELSTPKE------PTSTNPKEPEPT-LPK-------------EPELTLPEEPEP 738

  Fly  1054 REGELDGDLMAEFSEFNYQLA----KPEPEAPKEKRDDSKSNLSELQRLISNLQELQQLNVSLDQ 1114
            ...|...:|:||.:|.....|    ..||..|.|..:.||..::..:...:.....|.......:
  Rat   739 SNPETSDELIAELAEAPTPKALENNPKEPTVPTETPEVSKPEMTTAKEKTTEKDTTQTTTTVTPK 803

  Fly  1115 VTT-------ATSSPRPNPDAAYLQSLQ---SGQDETLK------------ERRQSVENVTTESG 1157
            .||       .|:.||.:.......:.|   |.|..|||            |..||....||.:.
  Rat   804 TTTETTIIPEETTEPRASTTTRITSTAQDTTSPQMTTLKATTLAAKVTAPTEEIQSKPEETTLTT 868

  Fly  1158 KQKDGDDPPPTT---QSPTKISLSLGLDDIDGDTKGAVGEDDSSSTSTTTTTEEPRNGSLDDLAD 1219
            ...:|.|...||   |.|||           ...|.|..:..:.:....|:|::|:.
  Rat   869 PALEGSDASKTTLKPQKPTK-----------APKKPASTKKPTKAPKKPTSTKKPKT-------- 914

  Fly  1220 SFGPDPVSEEP---PPPKKKNGFYFLADWNSF-LEV----------------------------G 1252
                 |...:|   |.|.|.:   .:::.|:. |||                            |
  Rat   915 -----PKGRKPKTTPSPLKTS---TMSEQNTTPLEVMLPTTTVPKQTPNSETAEVNPAHEDADGG 971

  Fly  1253 DGDDQVVVRLSPKIGDPRLFLPVKIP 1278
            :|:       .|.|..|.:..|..:|
  Rat   972 EGE-------KPLIPRPPVLSPTAVP 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11409	NP_569902.2	None
Prg4	NP_001099432.4	SO	26..68	CDD:197571
		Somatomedin_B	69..106	CDD:460034
		PHA03247	<315..724	CDD:223021	111/571 (19%)
		HX	1013..1274	CDD:238046