Protein Alignment DAAM and BNR1

DIOPT Version :10

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: NP_012107.1
• Gene: BNR1 / 854647
• SGDID: S000001421
• Length: 1375
• Species: Saccharomyces cerevisiae
• Alignment Length: 1324
• Identity: 275/1324 - (20%)
• Similarity: 494/1324 - (37%)
• Gaps: 381/1324 - (28%)

  Fly   379 SLPAQKKWQIYCSRKLPLDAADGPDAAAVTQPPTAEHYIERLKELVVHISLSPEDSPSHELGNRL 443
            ::..::||.:.|..:                  ::.|:.:  |::....:.|     :|...|.|
Yeast   126 NISLRRKWLLICKIR------------------SSNHWGK--KKVTSSTTYS-----THLATNEL 165

  Fly   444 DGHAAFVDALKTALRTS----------------THSFVLRFVELDGLPALLDLLLQLDIRVANSP 492
            ..:|.|:|.|...|.|.                ..||:..|::.:   ..|..|::..:.:.:..
Yeast   166 AENAHFLDGLVRNLSTGGMKLSKALYKLEKFLRKQSFLQLFLKDE---IYLTTLIEKTLPLISKE 227

  Fly   493 LHTSLIGCIKALMNNSMGRAHVLAHPTAIDTIARSLAAD---NIRTKIAALEILGAVCLVPGGHR 554
            |....:.|.|.||||.:.|...| |...:......|..|   |::.::.::|:|..:..|.|...
Yeast   228 LQFVYLRCFKILMNNPLARIRAL-HSEPLIRWFTELLTDQNSNLKCQLLSMELLLLLTYVEGSTG 291

  Fly   555 -KVLQAMLHFQVFATERTRFQSIVND---LDRSTYAYRD--NVNLKTALMSFVNAVL---NYGPG 610
             :::...|.. :|......|..|:.|   :..|.|...:  .::..|..:..:|::|   |....
Yeast   292 CELIWDQLSI-LFTDWLEWFDKILADDIAIHSSLYLNWNQLKIDYSTTFLLLINSILQGFNNKTA 355

  Fly   611 QENLEF----RLHLRYEFLMLG---------IQPVIDKLRTHENETLDRHLDFFEMVRAEDE--- 659
            .|.|.|    .:|....||.|.         |...|.:.::.|:...|      .|::..::
Yeast   356 LEILNFLKKNNIHNTITFLELAYKDDPNSVVIMEQIKQFKSKESAIFD------SMIKTTNDTNS 414

  Fly   660 ----KEFAR--------------RFKEEHVD---TKSAGSMFELLRRKLSHSPAYPHMLSLLQHM 703
                |:.||              :.|:..|:   .:...|::::|..:..:|.:. .:|.|:..:
Yeast   415 LHPTKDIARIESEPLCLENCLLLKAKDSPVEAPINEIIQSLWKILDSQKPYSESI-KLLKLINSL 478

  Fly   704 LLL----------PYTGHCTEHWLLIDRVVQQIVLQVEQRPNSD-----LIVDPDDPEKQLKLAA 753
            |..          |......|....:|.|.|..|.::.....||     .:.:.||...::....
Yeast   479 LFYLIDSFQVSTNPSFDETLESAENVDYVFQDSVNKLLDSLQSDEIARRAVTEIDDLNAKISHLN 543

  Fly   754 ES----PVHDPDVAPLQIDVAK-LVRLLVKE-----EQLTQARKRADE-------------LERE 795
            |.    ..||.|....::|.:: |:.|..||     .||...:||.|:             |...
Yeast   544 EKLNLVENHDKDHLIAKLDESESLISLKTKEIENLKLQLKATKKRLDQITTHQRLYDQPPSLASS 608

  Fly   796 NFDVQ--------------SRLAKKEQELDLRMQEKEDL---ETGLARMRE-----------RLE 832
            |..:.              ..||||:|:     |:|..|   .|.|.:.:.           ..|
Yeast   609 NLSIAGSIIKNNSHGNIIFQNLAKKQQQ-----QQKISLPKRSTSLLKSKRVTSLSSYLTDANNE 668

  Fly   833 KESAQHSQAVQRAQTAEMRAEDLQHRLIS----EQQERARLERLVTE-------GSIPDDQKVAG 886
            .||...|:...:....:.....:...:.|    ...:...|..:::|       |:.|:.|....
Yeast   669 NESQNESEDKSKDSLFQRSTSTINFNIPSMKNITNMQNVSLNSILSELEFSNSLGTQPNYQSSPV 733

  Fly   887 LTGCNGAVSP---------------------------PPAPPMLKAIPPPPPPMAPSMM------ 918
            |:..:.  ||                           ||.||     ||||||:..|::
Yeast   734 LSSVSS--SPKLFPRLSSDSLDNGIQLVPEVVKLPQLPPPPP-----PPPPPPLPQSLLTEAEAK 791

  Fly   919 --------PPPPPPCP--------GA---PPPPPSMAQTMA-------------PAPPKVD--LP 949
                    .|.|||.|        ||   |||||.:.::::             ||||..:  |.
Yeast   792 PDGVSCIAAPAPPPLPDLFKTKTCGAVPPPPPPPPLPESLSMNKGPSNHDLVTPPAPPLPNGLLS 856

  Fly   950 KKNV----------PQPTNP-LKSFNWSKLPDAKLQGTVW----------SELDESKLYNNMELE 993
            ..:|          |.||.. ||..:|.|:.|.|  .|:|          .||....:::  ::|
Yeast   857 SSSVSINPTTTDLKPPPTEKRLKQIHWDKVEDIK--DTLWEDTFQRQETIKELQTDGIFS--QIE 917

  Fly   994 SIDKLFS----AYQKNGVSATDGSYEDLRVTGKAAKQ-KVLSVIDGRRAQNCTILLSKL-KMSDM 1052
            .|.|:.|    |.::|..|:...|..:    ||::.: |.:|.:....||...|.|... ::|||
Yeast   918 DIFKMKSPTKIANKRNAESSIALSSNN----GKSSNELKKISFLSRDLAQQFGINLHMFSQLSDM 978

  Fly  1053 EISKAILSMDSNEQLQLDMVE--QLLKFTPSAE----ERALLDEH--------SEDIESLARADR 1103
            |....:|:.|:      |:|:  .:|||....|    .:::|:::        .:.:..|.||||
Yeast   979 EFVMKVLNCDN------DIVQNVNILKFFCKEELVNIPKSMLNKYEPYSQGKDGKAVSDLQRADR 1037

  Fly  1104 FLYE--ISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGN 1166
            ...|  |:...::..|.|||.....:.....||:.::..:.:|...:.||.:.:.|:.::..:||
Yeast  1038 IFLELCINLRFYWNARSKSLLTLSTYERDYYDLIFKLQKIDDAISHLNRSPKFKSLMFIITEIGN 1102

  Fly  1167 YMNRGARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKV 1231
            :||:..   ..|.:|.||.:||..:||..:..:.||::.:||..|:.|:....||:.::.:..|:
Yeast  1103 HMNKRI---VKGIKLKSLTKLAFVRSSIDQNVSFLHFIEKVIRIKYPDIYGFVDDLKNIEDLGKI 1164

  Fly  1232 SLGEMDKDIQMLRTGLADVAREIEFHRSS-----GPAQQGDRFLPVMREFHAQASVRFAELEDKF 1291
            ||..::.:.......:.|:..:.:..:.|     .|..|      ::::      |:|     |.
Yeast  1165 SLEHVESECHEFHKKIEDLVTQFQVGKLSKEENLDPRDQ------IIKK------VKF-----KI 1212

  Fly  1292 QDMKTR--------------FDRAVRLFGEDGSVLQ-PDEFFGIFDSFLAAFAEARHDNESFRRR 1341
            ...||:              .::.::.:|||....: .:|||..|..|||.|.:...:|     .
Yeast  1213 NRAKTKSELLIGQCKLTLIDLNKLMKYYGEDPKDKESKNEFFQPFIEFLAMFKKCAKEN-----I 1272

  Fly  1342 QEEEEKRAKQEAELKKRTIERKNKTGLMTSVARNLGLKSGSSNGDPDSPAKGGDNKGEFDDLISA 1406
            ::||.:|..:         :||:...:.||..:.   .:||...|.:..     |:...|.|||.
Yeast  1273 EKEEMERVYE---------QRKSLLDMRTSSNKK---SNGSDENDGEKV-----NRDAVDLLISK 1320

  Fly  1407 LRTGDVFGEDMAKFKRSRKARVLN 1430
            ||......|.:    |.||:..||
Yeast  1321 LREVKKDPEPL----RRRKSTKLN 1340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:461886	35/187 (19%)
		Drf_FH3	551..737	CDD:461885	41/241 (17%)
		Smc	<765..>875	CDD:440809	28/160 (18%)
		FH2	950..1328	CDD:396655	102/440 (23%)
BNR1	NP_012107.1	EnvC	510..>603	CDD:443969	19/92 (21%)
		FH2	868..1265	CDD:396655	101/430 (23%)