Protein Alignment DAAM and AFH14

DIOPT Version :10

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: NP_174461.3
• Gene: AFH14 / 840068
• AraportID: AT1G31810
• Length: 1230
• Species: Arabidopsis thaliana
• Alignment Length: 594
• Identity: 171/594 - (28%)
• Similarity: 274/594 - (46%)
• Gaps: 120/594 - (20%)

  Fly   886 GLTGCNGAVSPPPAP--------PMLKAIPPPPPPM-----------APSMMPPPPPPCPGA--- 928
            |.||......|||.|        |..|..||||||.           .||..||||||.|.|
plant   651 GSTGNKRQAQPPPPPPPPPPTRIPAAKCAPPPPPPPPTSHSGSIRVGPPSTPPPPPPPPPKANIS 715

  Fly   929 ----------------------PPPPPSMAQTMAPAPP---KVDLPK------------------ 950
                                  |||||.:::|.||.||   |..:|.
plant   716 NAPKPPAPPPLPPSSTRLGAPPPPPPPPLSKTPAPPPPPLSKTPVPPPPPGLGRGTSSGPPPLGA 780

  Fly   951 --KNVPQPTNP---------------------------LKSFNWSKLPDAKLQGTVWSELDESKL 986
              .|.|.|..|                           ||..:|||:..| .:|::|:  |..|.
plant   781 KGSNAPPPPPPAGRGRASLGLGRGRGVSVPTAAPKKTALKPLHWSKVTRA-AKGSLWA--DTQKQ 842

  Fly   987 YN-----NMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSK 1046
            .|     .:::..::.||||     ||.|.......|.....:|.:.:.::|.|||.||.|:|:|
plant   843 ENQPRAPEIDISELESLFSA-----VSDTTAKKSTGRRGSSISKPEKVQLVDLRRANNCEIMLTK 902

  Fly  1047 LKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRFLYEISKI 1111
            :|:...::..|:|::|| ..|.:|.||.|:||.|:.||..||..::.|.|.|.:.::|..|:.|:
plant   903 IKIPLPDMLSAVLALDS-LALDIDQVENLIKFCPTKEEMELLRNYTGDKEMLGKCEQFFMELMKV 966

  Fly  1112 PHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRG-ARGN 1175
            |..|.:|:...:|..|...:.:|...:.::..|::||..|.:||::::.:|.|||.:|:| |||:
plant   967 PRIEAKLRVFGFKITFASQVEELKSCLNTINAATKEVKESAKLRQIMQTILTLGNALNQGTARGS 1031

  Fly  1176 ASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDI 1240
            |.||:|.||.:|:||::...| .||:|||.:::..|..:||...:|:.|:..|||:.|..:.:::
plant  1032 AVGFKLDSLLKLSDTRARNNK-MTLMHYLCKLVGEKMPELLDFANDLVHLEAASKIELKTLAEEM 1095

  Fly  1241 QMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLF 1305
            |....||..|.:|:....:.|....|  |..|::||...|......|...:.::....|.....|
plant  1096 QAATKGLEKVEQELMASENDGAISLG--FRKVLKEFLDMADEEVKTLASLYSEVGRNADSLSHYF 1158

  Fly  1306 GEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQEAELKKRTIERK----NKT 1366
            |||.:....::...|...|:..|.::|.:||    :|.|.||:..::..:|:::..:|    |..
plant  1159 GEDPARCPFEQVTKILTLFMKTFIKSREENE----KQAEAEKKKLEKEAIKEKSATKKDGVDNDN 1219

  Fly  1367 GLMTSVARN 1375
            .|:..:.|:
plant  1220 DLIQQIHRH 1228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:461886
		Drf_FH3	551..737	CDD:461885
		Smc	<765..>875	CDD:440809
		FH2	950..1328	CDD:396655	121/430 (28%)
AFH14	NP_174461.3	PTP_DSP_cys	21..190	CDD:475123
		PTEN_C2	198..338	CDD:463081
		FH2	814..1181	CDD:396655	117/378 (31%)