DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DAAM and Fh5

DIOPT Version :9

Sequence 1:	NP_001188522.1	Gene:	DAAM / 31075	FlyBaseID:	FBgn0025641	Length:	1463	Species:	Drosophila melanogaster
Sequence 2:	NP_200276.1	Gene:	Fh5 / 835554	AraportID:	AT5G54650	Length:	900	Species:	Arabidopsis thaliana

Alignment Length:	851	Identity:	212/851 - (24%)
Similarity:	326/851 - (38%)	Gaps:	204/851 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   656 AEDEKEFARRFKEEHVDTKSAGSMFELLRRK---LSHSPAYPHMLSLLQHMLLLPYTGHCTEHWL 717
            ::|.:|.   |...|.:.|.  ::.:.::.|   ..|:|.|   |.||..||.:|.....|
plant    88 SKDSREL---FGLNHTNLKQ--TLLDCIQEKGKLNGHNPKY---LELLSSMLDIPRRNLAT---- 140

  Fly   718 LIDRVVQQIVLQVEQRPNSDLIVDPDDPEKQL---------------KLAAESPVHDPDVAPLQI 767
                           :|.|.....|..|.|:.               :.::..|...|...|.:.
plant   141 ---------------KPGSSPSPSPSRPPKRSRGPPRPPTRPKSPPPRKSSFPPSRSPPPPPAKK 190

  Fly   768 DVAKLVRLLVKEEQLTQARKRADE-----------------LERENFDVQSRL------AKKEQE 809
            :.:|    ......::.|:|:.|.                 |....|...||:      .:|..|
plant   191 NASK----NSTSAPVSPAKKKEDHEKTIIIAVVVTAVSTFLLAALFFLCCSRVCGNGSGGRKNDE 251

  Fly   810 LDLRMQEKEDLETGLARMRERLEKESAQHSQAVQ-RAQTAEMRAEDLQHRLISEQQERARLERLV 873
            ..|......|...|.:.......|...|..|:.. .:...:|.:.|..:...|:..|    |||.
plant   252 RPLLSLSSSDYSVGSSINYGGSVKGDKQGHQSFNIYSNQGKMSSFDGSNSDTSDSLE----ERLS 312

  Fly   874 TEG----SI----------PDDQKVAGLTG--CNGAVSP-PPAPPML------KAIPPPPPPMAP 915
            .||    ||          |..:..:.|:|  .:|.|.| ||.||..      ||..||||..||
plant   313 HEGLRNNSITNHGLPPLKPPPGRTASVLSGKSFSGKVEPLPPEPPKFLKVSSKKASAPPPPVPAP 377

  Fly   916 SM-------MPPPPPPCPGA----PPPPPSMAQTMAPAP----PKVDLPKKNVPQ------PTNP 959
            .|       .||||.|.||:    |||||.......|.|    ||...|......      |...
plant   378 QMPSSAGPPRPPPPAPPPGSGGPKPPPPPGPKGPRPPPPMSLGPKAPRPPSGPADALDDDAPKTK 442

  Fly   960 LKSFNWSKLPDAKLQGTVWSELDESKLYNNMELESIDKLFSAYQKNGVSATDGSYEDLR-VTGKA 1023
            ||.|.|.|:........||:::.......|.|:  |:.||      |.:|.|.:..|.: .:|:|
plant   443 LKPFFWDKVQANPEHSMVWNDIRSGSFQFNEEM--IESLF------GYAAADKNKNDKKGSSGQA 499

  Fly  1024 AKQKVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALL 1088
            |..:.:.:::.::.||.:|||..|..:..|:..|:  .:.|| |.::.::.|||..|:.||...|
plant   500 ALPQFVQILEPKKGQNLSILLRALNATTEEVCDAL--REGNE-LPVEFIQTLLKMAPTPEEELKL 561

  Fly  1089 DEHSEDIESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVME----ASREVA 1149
            ..:..:|..|..|:|||..:..||...:||::|    .||.|:::.:..:....:    |.:|:.
plant   562 RLYCGEIAQLGSAERFLKAVVDIPFAFKRLEAL----LFMCTLHEEMAFVKESFQKLEVACKELR 622

  Fly  1150 RSRRLRKLLELVLALGNYMNRGA-RGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIER--- 1210
            .||...||||.||..||.||.|. ||.|..|:|.:|.:|||.|.:..| |||||::||.|.|
plant   623 GSRLFLKLLEAVLKTGNRMNDGTFRGGAQAFKLDTLLKLADVKGTDGK-TTLLHFVVQEIIRTEG 686

  Fly  1211 ----------------KFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADV---AREIEF 1256
                            |.:|||        |.|.|:    |.:::.:.|  ||..|   :.|:|.
plant   687 VRAARTIRESQSFSSVKTEDLL--------VEETSE----ESEENYRNL--GLEKVSGLSSELEH 737

  Fly  1257 HRSSGPAQQGDRFLPVMREFHAQASVR-FAELEDKFQDMKTRFDRAVRLF--GEDGSVLQPDEFF 1318
            .:.|...........|::..||.:..| |...|.|....::.|..|:..|  ..:||::
plant   738 VKKSANIDADGLTGTVLKMGHALSKARDFVNSEMKSSGEESGFREALEDFIQNAEGSIM------ 796

  Fly  1319 GIFDSFLAAFAEARHDNESFRRRQEEEE----------------KRAKQEAELKKRTIERKNKTG 1367
            .|.:......|..:...:.|..:..::|                |..|:..|.:.|.:....|.|
plant   797 SILEEEKRIMALVKSTGDYFHGKAGKDEGLRLFVIVRDFLIILDKSCKEVREARGRPVRMARKQG 861

  Fly  1368 LMTSVA 1373
            ...|.:
plant   862 STASAS 867

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920
		Drf_FH3	551..737	CDD:283917	17/83 (20%)
		FliJ	779..>875	CDD:280262	22/119 (18%)
		FH2	950..1328	CDD:280362	115/414 (28%)
Fh5	NP_200276.1	FH2	435..840	CDD:280362	118/440 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I2015
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.870