DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DAAM and AT5G07760

DIOPT Version :9

Sequence 1:	NP_001188522.1	Gene:	DAAM / 31075	FlyBaseID:	FBgn0025641	Length:	1463	Species:	Drosophila melanogaster
Sequence 2:	NP_001331313.1	Gene:	AT5G07760 / 830669	AraportID:	AT5G07760	Length:	867	Species:	Arabidopsis thaliana

Alignment Length:	873	Identity:	178/873 - (20%)
Similarity:	280/873 - (32%)	Gaps:	400/873 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly   887 LTGCNGAVSPP-------PAPPMLKAIPPPPPPM---APSMMPPPPPP-----CPGAPPPPPSMA 936
            ::|.:..||||       |.||     |||||||   ||  :||||||     .|..|||||:|.
plant     6 ISGADAVVSPPMRGRVPLPPPP-----PPPPPPMRRRAP--LPPPPPPPMRRRAPLPPPPPPAMR 63

  Fly   937 QTMAPAPPKVDLP------------------KKNVPQPTNP------------------------ 959
            :.:.|.||....|                  ::..|.|..|
plant    64 RRVLPRPPPPPPPLPMFDAEVLCCCYPPTRVRREAPLPPPPLIFVGAPPPTCALKGIVCCFPCPS 128

  Fly   960 -----LKSFNWSKLPDAKLQGTVWSEL-------------------------------------- 981
                 ||.|||.|:..| |.|::|.||
plant   129 KKKSSLKRFNWVKITRA-LPGSLWDELQIQQVCHGDIEDEQILCAIELDVSEIETFFSLGAAKPE 192

  Fly   982 -----------------------------------DESKL--------------YNNME------ 991
                                               |||.|              ..|||
plant   193 KDPLIDLRRATDTELTLMLLNIRLPADMMAAIMAMDESVLDDDEIRGLINLFPTKENMELLMSYT 257

  Fly   992 ----------------------------------------------------------------- 991

plant   258 GGKWTLEKWEQYFQELRKVLRVESKLRVFYFKIQFSTKITQFKKRLNVVNSACEEVCSSQKLKEI 322

  Fly   992 --------------------------------------------------------LESIDK--- 997
                                                                    |||..|
plant   323 MKKITCLGNTSNQGTGRGVTVGFNLDSLCVKSMHNFCKVLASEASDLLDVHKDLQSLESASKKQL 387

  Fly   998 ------------------------------------------------------LFSAYQKNGVS 1008
                                                                  |:|...||.|:
plant   388 KSLAEEMQDIIRDLEKLNQELTAAETDGPDSQVFRNTLKDFISIAETEVKTVLSLYSVVGKNAVA 452

  Fly  1009 ATDGSYED----------------LRVTGKAAKQKV----------------------------- 1028
            ..:...||                :|:..||.::.|
plant   453 LVNYFGEDPKWCPFEQVTATLLHFIRLFEKAHEENVKKADLEKKKAANETEMKHVVHNSWLNNLN 517

  Fly  1029 ---LSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDE 1090
               .::||.|||.|..|:|.|::|...::..|:|.||.: .|.:|.:|.|::|.|:.||..||..
plant   518 IRASTLIDQRRAFNTMIMLQKVEMPLPDMMAAVLGMDES-VLDVDQIENLIRFCPTKEEMKLLKN 581

  Fly  1091 HSEDIESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLR 1155
            ::.|..:|.:.:::..|:.|:|..|.:|:...:|..|...|.:|...:.:|..|..|:..|::|:
plant   582 YTGDKATLGKCEQYFLELMKVPGVESKLRVFSFKIHFGTQIKELNKGLNTVNSACEEIRTSQKLK 646

  Fly  1156 KLLELVLALGNYMNRG-ARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLE 1219
            ::::::|.|||.:|:| |||:|.||:|.||..|:: |.||....||:|||.:|:..|..|||...
plant   647 EIMKIILCLGNILNQGTARGSAVGFKLDSLLNLSE-KCSANTNMTLMHYLCKVLASKASDLLDFH 710

  Fly  1220 DDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRF 1284
            .|:.::..|||:.|..:.:::..:..||..:.:|:....|.||.  .:.|..::::|.:.|..:.
plant   711 KDLENLESASKIHLKSLAEEMVAITKGLQKLNQELTASESDGPI--SEVFRKLLKDFISVAETQV 773

  Fly  1285 AELEDKFQDMKTRFDRAVRLFGEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRA 1349
            |.:...:..:....|..|..||||.:....::......||:..|..|.|....  ::.|.|:|:|
plant   774 ATVSSLYSSVGGNTDALVHYFGEDPNDYPFEQVTATLLSFVRLFTTAAHQENV--KQAELEKKKA 836

  Fly  1350 KQEAELKKRTIERKNKTGLMTSVARNLG 1377
            .:|||::|    .|.:..|....|..:|
plant   837 AKEAEMEK----TKKRVSLTNKKASGVG 860

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920
		Drf_FH3	551..737	CDD:283917
		FliJ	779..>875	CDD:280262
		FH2	950..1328	CDD:280362	129/726 (18%)
AT5G07760	NP_001331313.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	185	1.000	Domainoid score	I993
eggNOG	1	0.900	-	-		E1_KOG1922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	1	1.000	-	-		otm2452
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820