DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DAAM and AT5G07650

DIOPT Version :9

Sequence 1:	NP_001188522.1	Gene:	DAAM / 31075	FlyBaseID:	FBgn0025641	Length:	1463	Species:	Drosophila melanogaster
Sequence 2:	NP_196382.2	Gene:	AT5G07650 / 830658	AraportID:	AT5G07650	Length:	815	Species:	Arabidopsis thaliana

Alignment Length:	819	Identity:	179/819 - (21%)
Similarity:	311/819 - (37%)	Gaps:	247/819 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   715 HWLLIDRVVQQIVLQVEQRPNSD--------------LIVDPDDPEK----QLKLAA-------- 753
            ||:.|...:|..:....||.:.|              |......|||    .|:.|:
plant    66 HWVKITSDLQGSLWDELQRRHGDSQTAIELDISELETLFFVEAKPEKIRLHDLRRASYRVFNVRS 130

  Fly   754 ------------ESPVHDPDVAPLQID--------VAKLVRLLVKEEQLTQARKRADELERENFD 798
                        ..|:.|...|.|.:|        :.||::.....|::        ||.:....
plant   131 YYMRANNKVINLSMPLPDMMTAVLAMDESVVDVDQIEKLIKFCPTNEEM--------ELLKTYTG 187

  Fly   799 VQSRLAKKEQ-----------ELDLRM-QEKEDLETGLARMRERLEKESAQHSQAVQRAQTAEMR 851
            .::.|.|.||           |..||: ..|....|.:..::|||.         |..:...|:|
plant   188 DKAALGKYEQYLLELMKVPRLEAKLRVFSFKTQFGTKITELKERLN---------VVTSACEEVR 243

  Fly   852 AEDLQHRLISEQQERARLERLV--------TEGSIPD-------DQKVAGLTGCNGAVSPPPAPP 901
            :.:             :|:.::        |....||       |:.::..:|..       ...
plant   244 SSE-------------KLKEIMKKIPCLGNTSNQGPDRGKSSVVDKNLSFSSGIQ-------LKE 288

  Fly   902 MLKAIPPPPPPMAPSMMPPPPPPCPGAPPPPPSMAQTMAPAPPKVDLPKKNVPQPTNPLKSFNW- 965
            ::|.|                 ||.|          ..:.:.|:|.:...:....|:.:||.::
plant   289 IMKKI-----------------PCLG----------NTSKSNPRVGVKLDSSVSDTHTVKSMHYY 326

  Fly   966 --------SKLPDA------------------------------KL-QGTVWSELD--ESKLYNN 989
                    |:|.|.                              || |....||.|  .|:::.|
plant   327 CKVLASEASELLDVYKDLQSLESASKIQVKSLAQNIQAIIKRLEKLKQELTASETDGPASEVFCN 391

  Fly   990 ----------MELESIDKLFSAYQKN--------GVSATDGSYEDLRVT---------------- 1020
                      .|:.::..|:|..:|.        |.......:|.|.:|
plant   392 TLKDFISIAETEMATVLSLYSVVRKKADALPPYFGEDPNQCPFEQLTMTLFNFIKLFKKAHEENV 456

  Fly  1021 --GKAAKQKVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAE 1083
              ....|:|.:..||.|||.:..|:|:|:.:...::..|:|.|| ...|.:|.:|.|::|.|:.|
plant   457 KQADLEKKKAMKQIDLRRANDTEIMLTKVNIPLADMMAAVLGMD-EYVLDVDQIENLIRFCPTKE 520

  Fly  1084 ERALLDEHSED------IESLARA------------------DRFLYEISKIPHYEQRLKSLHYK 1124
            |..||..::.|      .|.||:|                  .::..|:.|:|..|.:|::..:|
plant   521 EMELLKNYTGDKATLGKCEQLAKAKAPLKEHFRVINAFPSLTPQYFLEVMKVPGVESKLRAFSFK 585

  Fly  1125 KRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRG-ARGNASGFRLASLNRLA 1188
            .:|...|.:|...:.:|..|..||..|.:|::::..:|.:||.:|:| |.|:|.||:|.||..|:
plant   586 IQFGTQIAELNKGLNAVNSACEEVRTSEKLKEIMANILCMGNILNQGTAEGSAVGFKLKSLLILS 650

  Fly  1189 DTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADVARE 1253
            ||.:..:| .||:|||.:|:..|..|||....|:..:..|||:.|..:.::||.:..||..:.::
plant   651 DTCAPNSK-MTLMHYLCKVLASKASDLLDFHKDLESLESASKIQLKSLAEEIQAITKGLEKLNKQ 714

  Fly  1254 IEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGSVLQPDEFF 1318
            :....|.||..|  .|..|:::|.:.|..:.|.:...:..:....|.....||||.:....::..
plant   715 LTASESDGPVSQ--VFRKVLKDFISMAETQVATVSSLYSSVGKNADALAHYFGEDPNHYPFEKVT 777

  Fly  1319 GIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQEAELKK 1357
            ....||:..|.:|..:|  .::...::.|.|| |||::|
plant   778 TTLLSFIRLFKKAHEEN--VKQADLDKNKDAK-EAEMEK 813

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920
		Drf_FH3	551..737	CDD:283917	6/21 (29%)
		FliJ	779..>875	CDD:280262	19/115 (17%)
		FH2	950..1328	CDD:280362	118/480 (25%)
AT5G07650	NP_196382.2	FH2	54..449	CDD:366959	73/446 (16%)
AT5G07650	NP_196382.2	FH2	462..788	CDD:366959	96/329 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	185	1.000	Domainoid score	I993
eggNOG	1	0.900	-	-		E1_KOG1922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	1	1.000	-	-		otm2452
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820