Protein Alignment DAAM and AFH1

DIOPT Version :10

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: NP_189177.1
• Gene: AFH1 / 822136
• AraportID: AT3G25500
• Length: 1051
• Species: Arabidopsis thaliana
• Alignment Length: 729
• Identity: 172/729 - (23%)
• Similarity: 281/729 - (38%)
• Gaps: 204/729 - (27%)

  Fly   731 EQRPNSDLIVDPDDPEKQLKLAAESPVH-------------DPDVAPLQIDVAKLVRLLVKEEQL 782
            |:|||       |.||..|:    ||.|             .|:|.|..:            ..|
plant   388 ERRPN-------DTPEAYLR----SPSHSSASTSPYRCFQKSPEVLPAFM------------SNL 429

  Fly   783 TQARKRADELERENFDVQSRLAKKE----------QELD-LRMQEKEDLETGLARMRERLEKESA 836
            .|.             :||:|....          ::|| ||.:......:.:..     ..|.|
plant   430 RQG-------------LQSQLLSSPSNSHGGQGFLKQLDALRSRSPSSSSSSVCS-----SPEKA 476

  Fly   837 QHSQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVTEGSIPDDQKVAGLTGCNGAVSP---PP 898
            .|...|...:.:...::.|                    .|.||......|.     |||   ..
plant   477 SHKSPVTSPKLSSRNSQSL--------------------SSSPDRDFSHSLD-----VSPRISNI 516

  Fly   899 APPMLKAIPPPPPPMAPSMMPPPPPPCPGAPPPPPSMAQTMA-------PAPPKVDLPKKNVPQP 956
            :|.:|::..|||||      ||||.|..|......:.|.|::       |:.|.| :|.:|:|..
plant   517 SPQILQSRVPPPPP------PPPPLPLWGRRSQVTTKADTISRPPSLTPPSHPFV-IPSENLPVT 574

  Fly   957 TNP--------------------LKSFNWSKLPDAKLQGTVWSELDESKLYNNMELESIDKLFSA 1001
            ::|                    ||:.:|.|:..:..:..||..|..|..  .::.|.|:.||.|
plant   575 SSPMETPETVCASEAAEETPKPKLKALHWDKVRASSDREMVWDHLRSSSF--KLDEEMIETLFVA 637

  Fly  1002 YQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQ 1066
            ...|  :..:.|....|....:..|: ..|:|.::|||..|||..|.::..|:.:|:|..:: :.
plant   638 KSLN--NKPNQSQTTPRCVLPSPNQE-NRVLDPKKAQNIAILLRALNVTIEEVCEALLEGNA-DT 698

  Fly  1067 LQLDMVEQLLKFTPSAEERALLDEHSEDIE-SLARADRFLYEISKIPHYEQRLKSLHYKKRFMLT 1130
            |..:::|.|||..|:.||...|..:::|.. .|..|::||..:..||...:|:.::.|...|...
plant   699 LGTELLESLLKMAPTKEEERKLKAYNDDSPVKLGHAEKFLKAMLDIPFAFKRVDAMLYVANFESE 763

  Fly  1131 INDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGA-RGNASGFRLASLNRLADTKSSA 1194
            :..|.....::..|..|:..||...||||.||..||.||.|. ||:|..|:|.:|.:|.|.|.:.
plant   764 VEYLKKSFETLEAACEELRNSRMFLKLLEAVLKTGNRMNVGTNRGDAHAFKLDTLLKLVDVKGAD 828

  Fly  1195 AKGTTLLHYLVQVIER----------------KFKDL-----LKLEDDIPHVREASKVSLGEMDK 1238
            .| |||||::||.|.|                |.:.|     ..|..::.:|::|:.:....:..
plant   829 GK-TTLLHFVVQEIIRAEGTRLSGNNTQTDDIKCRKLGLQVVSSLCSELSNVKKAAAMDSEVLSS 892

  Fly  1239 DIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRA-- 1301
            .:..|..|:|.:...|:...:            :..|.::|   ||:|      .|||...||
plant   893 YVSKLSQGIAKINEAIQVQST------------ITEESNSQ---RFSE------SMKTFLKRAEE 936

  Fly  1302 --VRLFGEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQEAELKKRTIERKN 1364
              :|:..::...|          |.:....|..|.|.            ||:||...:..:..::
plant   937 EIIRVQAQESVAL----------SLVKEITEYFHGNS------------AKEEAHPFRIFLVVRD 979

  Fly  1365 KTGLMTSVARNLGL 1378
            ..|::..|.:.:|:
plant   980 FLGVVDRVCKEVGM 993

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:461886
		Drf_FH3	551..737	CDD:461885	4/5 (80%)
		Smc	<765..>875	CDD:440809	14/120 (12%)
		FH2	950..1328	CDD:396655	108/424 (25%)
AFH1	NP_189177.1	FH2	591..985	CDD:396655	113/443 (26%)