Protein Alignment DAAM and fmn2a

DIOPT Version :9

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: XP_001333061.4
• Gene: fmn2a / 793321
• ZFINID: ZDB-GENE-101107-1
• Length: 1465
• Species: Danio rerio
• Alignment Length: 1483
• Identity: 310/1483 - (20%)
• Similarity: 527/1483 - (35%)
• Gaps: 383/1483 - (25%)

  Fly    91 AAGVTKITITSDNGNGNASTSTKAPTTGSSIDGYKNSS-----LVSITSLNSCSDLSQGSTATLP 150
            |.||..:.|.     ||.....|.||..:..:|..|.:     :..|....|.::
Zfish   169 AKGVRLLRIM-----GNQEAKQKKPTVTTGAEGEGNGAGTEDHVKKIKKSKSSAE---------- 218

  Fly   151 ISSNSCSGNNVSRHPLSNNNSGSDTSSNNFQERFDFEHWKGL----LSDYNCFHGLYRYWTQCSG 211
                  ||...|:   |..:.||..|  |.:.|      |||    ||..:...|..|    ...
Zfish   219 ------SGKKKSK---SEGSKGSVFS--NIRIR------KGLSRKVLSKEDVLDGGIR----IKP 262

  Fly   212 RSSSANDNGGGSDQQQSQSNHENGLGSEAGSFYTHNILGYTFGYPFGLKEDLDGSGNCNSNCNGS 276
            ..::.|.|||.|..:....:.:. |.:|:    ..:.|..|   ...::.:.:|||:....|:..
Zfish   263 ADANGNSNGGISGDESCMPDSKQ-LTAES----RQSTLDTT---EDDVERETEGSGSDTDLCSYH 319

  Fly   277 SNTNGLGLRKWLSGNTSSNETPLQKHYRH-QQKKKMPGFRGR--------RVWCGCFKDDEPPEI 332
            |......|...:.......|...::...| :.|::..||.|.        |....|  :.||.::
Zfish   320 SAAEAQDLLSDIQRTIRQMEGVDERQNCHSEDKERQVGFEGHVEVTHGPTRGSLAC--EGEPEKL 382

  Fly   333 CVVEGAFTLQTLTPTQPMPSVDELDTKFAELVEELDLTA------------------PNKEAMLS 379
               |||                 .|:|:..|:...|.|.                  |||...||
Zfish   383 ---EGA-----------------SDSKYLNLICSGDTTGGVITSKLKIESDGKVADIPNKADHLS 427

  Fly   380 LPAQKKWQIYCSRKLPLDAADGPDAAAVTQPP----------TAEHYIERLKELVVHISLSPEDS 434
            ..:..    |..:....:.....||.|.|...          |:..| |..:|::...|||....
Zfish   428 SLSSD----YSIQDAVPETNSVQDARAFTHSTSNYSFQDNTGTSTSY-ESAEEILESSSLSSPLE 487

  Fly   435 PSHELGNRLDGHAAFVDALKTALRTSTHSFVLRFVELDGLPALLDLLLQLDIRVANSPLHTSLIG 499
            ..|...|.|      ..:|:..|.:|.|...:.                   ||...|..:
Zfish   488 ECHYDSNSL------TQSLEVGLNSSNHMSKIN-------------------RVIFVPQKS---- 523

  Fly   500 CIKALMNNSMGRAHVLAHPTAIDTIARSLAADNIRTKIAALEILGAVCLVPGGH-RKVLQAMLHF 563
             |.::..|..|...|........|..|..::....|:.::...||:     |.. |:...|.|..
Zfish   524 -ISSVELNVDGDGPVEEVDRGFSTQPRRKSSAASMTQWSSENFLGS-----GSRPRRTSSANLGV 582

  Fly   564 QVFATERTRFQSIVNDLDRSTYAYRDNVNLKTALMSFVNAV------------------LNYGPG 610
            :.:.|.:|.:                   :||......:.:                  |.:|.|
Zfish   583 KPYPTIQTSY-------------------VKTTTRQLTSPIISPFTTPSPSPMCPRKVGLEFGTG 628

  Fly   611 QENL---EFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFFEMVRAEDEKEFARRFKEEHVD 672
            |...   .:|...:....:.|  ||    ..|| |..:...|..|::.:..:.:.:|:......|
Zfish   629 QGPYRAGSWRARRQRSCSIAG--PV----GCHE-EWCEVIHDQSELIESGFQTDRSRQTTSTFPD 686

  Fly   673 TKSAGSMFELLRRKLSHSPAYPHMLSLLQHMLLLPYTGHCTEHWLLIDRVVQQIVLQVEQRPNSD 737
            ..|..|:.|....:.|.|.....|..:.:         .|:       |::...:||    |.||
Zfish   687 VFSGSSLLERCFLQWSSSEDDSAMQDIER---------FCS-------RILDLGILQ----PFSD 731

  Fly   738 LIVDP-------DDP---EKQLKLAAESPVHD------------PDVAPLQ-------------- 766
            .|.:|       |.|   :.||...|....||            |.:...|
Zfish   732 CIREPSTGSDVTDKPTFSKDQLYTWAPMGQHDIRTPGRLQRIWPPTLTAAQDGSTGQSGSVLEGS 796

  Fly   767 -IDVAKLVRLLVKEEQLTQARKRADELERENFDVQSRLAKKEQELDLRMQEKEDLETGLARMRER 830
             :.:.:|      |:.:.:..::..|:|::|..|..:|.:|::|:....|..:..:....|:
Zfish   797 SVSIQEL------EQTIEELLEKISEIEKDNHVVDGKLGRKDREVAGFNQTIKQTKVNGQRV--- 852

  Fly   831 LEKESAQHSQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVTE-------------------- 875
                 ..|.:|:|.:...|.....:.   :|.|.:..:|....|.
Zfish   853 -----LHHVKAIQTSPVEEAFKFPVP---LSHQSQTPKLSDSATSPMGLPYTCSCQRTTSQPLST 909

  Fly   876 ---GSIPDDQKVAGLT--GCNGAVSP-----------------PPAPPMLKAIPPPPPPMAPSMM 918
               ..:|....:.|:|  ...|.:.|                 ||.||:...:||||||: |.|.
Zfish   910 PPPPQLPPPPPLPGMTLPKPTGVIPPPPPLPGFVPPPPVVGKAPPPPPLPGMVPPPPPPL-PGMA 973

  Fly   919 PPPPPPCPG----APPPPPSMAQTMAPAPPKV-----------------DLPKKNVPQPTNPLKS 962
            ||||||.||    .|||||.......|.||.:                 .:|.|.|.:|..|:|.
Zfish   974 PPPPPPLPGMTPPPPPPPPGCGPPAPPLPPGIGPPPPFMGMGPPGMAHESVPLKAVIEPPRPMKP 1038

  Fly   963 FNWSKL-----PDAKLQGTVWSELDESKLYNNMELESIDKLFSAYQKNGVSATDGSYEDLRVTGK 1022
            ..|:::     .||| ...||..:.|..:       ..|:....:.|:.|........| .:|..
Zfish  1039 LYWTRIQLHAKKDAK-SALVWENVQEPSV-------DFDEFVEMFAKSAVKEKKKPISD-TITKS 1094

  Fly  1023 AAKQKVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERAL 1087
            .||| |:.::..:|:|...||:|.|.:...:|..|||:||.. .:.|:.::.|.:.....||...
Zfish  1095 KAKQ-VVKLLSNKRSQAVGILMSSLHLDMKDIQNAILNMDCT-VVDLETLQALYENRAQKEEMDQ 1157

  Fly  1088 LDEH---SEDIES---LARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASR 1146
            :::|   |:|.|.   |.:.::||.::|::|.:..|:..:.::..|...:..:..::.::.....
Zfish  1158 IEKHVKSSKDKEKPKPLDKPEQFLLQLSEVPQFSGRVFCILFQSTFTECVTSVQRKLETLGRVCT 1222

  Fly  1147 EVARSRRLRKLLELVLALGNYMNRG--ARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIE 1209
            .:...:.:.::|.||||.||.||.|  :||.|.||.|..|.:|.|.||| ....:||.|:|....
Zfish  1223 ALQSGQAVLQILGLVLAFGNIMNGGNRSRGQADGFSLDILPKLKDVKSS-DNSQSLLSYIVAYYL 1286

  Fly  1210 RKFKDLLKLED---DIPHVR---EASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDR 1268
            |.|.:....|.   .:|..:   :||::...:..:|::.||..|...:.|.|...:....:....
Zfish  1287 RHFDEDAGKETCTYPLPEPQDLFQASQMKFEDFQRDLRKLRKDLNACSAEREKVCNISSDEHLQP 1351

  Fly  1269 FLPVMREFHAQASVRFAELEDK--------FQDMKTRFDRAVRLFGEDGSVLQPDEFFGIFDSFL 1325
            |...|.:|..:|.... ||::|        |.::...|....:. ||  ..:.|:.||.::..|.
Zfish  1352 FKDKMDDFLTKAKTEL-ELQEKQLTDTQRIFLELSVFFSVKPKA-GE--KEVSPNTFFTVWHEFS 1412

  Fly  1326 AAFAEA-RHDNES-FRRRQEEEEKRAKQEAELKKRTIERKNKTGLMTSVARNL 1376
            :.|.|. :.:|:| .:.|.:..|:..||..|.....::.|..:|:...:.:.:
Zfish  1413 SDFKELWKRENKSLLQERLKAAEETFKQAREKATYNVKPKQASGIKAKLGQKM 1465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920	41/226 (18%)
		Drf_FH3	551..737	CDD:283917	34/207 (16%)
		FliJ	779..>875	CDD:280262	17/95 (18%)
		FH2	950..1328	CDD:280362	101/404 (25%)
fmn2a	XP_001333061.4	FH2	1027..1416	CDD:280362	101/404 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810