Protein Alignment DAAM and inf2

DIOPT Version :10

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: NP_001072591.1
• Gene: inf2 / 780046
• XenbaseID: XB-GENE-5862185
• Length: 1380
• Species: Xenopus tropicalis
• Alignment Length: 1111
• Identity: 276/1111 - (24%)
• Similarity: 480/1111 - (43%)
• Gaps: 229/1111 - (20%)

  Fly   424 VVHISLSPEDSPSHELGN----------RLDGHAAFVD--ALKTALRTSTHSFVLRFVELDGLPA 476
            |:...|.|:| |....||          ||....:.|:  .||..|.:|...::::|:||.||..
 Frog    13 VLKQKLGPQD-PEQIEGNMENADPELCIRLLQIPSVVNYSGLKKRLESSDDDWMVQFLELSGLDL 76

  Fly   477 LLDLLLQLD----IRVANSPLHTSLIGCIKALMNNSMGRAHVLAHPTAIDTIARSLAADNIRTKI 537
            ||:.|.:|.    .|:|::.|..:.|.|::.|||:..|..:::.:...:..::::|...|:..|.
 Frog    77 LLEALDRLSGRGVARIADALLQLTCINCVRTLMNSHRGIEYIVNNEGYVRKLSQALDTSNVMVKK 141

  Fly   538 AALEILGAVCLV-PGGHRKVLQAMLHFQVFATERTRFQSIVNDLDRSTYAYRDNVNLKTALMSFV 601
            ...|:|.|:|:. |.||...|.|:.|::....::.||..|:|:|..|     |||.....|:|.:
 Frog   142 QVFELLAALCIYSPEGHALSLDALEHYKAVKNQQYRFSVIMNELSTS-----DNVPYMVTLLSAI 201

  Fly   602 NAVLNYGPGQENLEFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFFEMVRAEDEKEFARRF 666
            ||::.   |.|.|..|:.||.||:.|.:..::.|||..|:|.|......||..::|||:|..:.:
 Frog   202 NAIIF---GTEELRKRVQLRNEFIGLQLLDLLTKLRDLEDEDLLIQAIVFEEAKSEDEEELLKIY 263

  Fly   667 KEEHVDTKSAGSMFELLRRKLSHSPAYPHMLSLLQHMLLLPYTGHCTEH--WLLIDRVVQQIVLQ 729
              ..:|..:...:|..|..|:|.||....:||:||.:|.|..: |.:..  |..:|.:|.:.||.
 Frog   264 --GGIDMNNHQEVFSTLFNKVSCSPLSVQLLSVLQGLLHLDQS-HPSSPLLWEALDILVNRAVLL 325

  Fly   730 VE--QRPNSDLIVDPDDPEKQLKLAAESPVHDPDVAPLQIDVAKLVRLLVKEEQLTQARKRADEL 792
            .:  |..|.:.::|                                ||:..::..::.:::.|:.
 Frog   326 ADDCQNNNVEEVMD--------------------------------RLVTSKKHPSKEKRKPDKC 358

  Fly   793 ERE-NFDVQSRLAKKEQELDLRMQEKEDLETGL----ARMRERL----------------EKESA 836
            ..: |..:|:. ..|::..:.:..:|:.:.:|:    .::.:.|                :..|.
 Frog   359 TNQVNKSIQTD-KPKDESCEEKTVKKDPVSSGIPADSLQLSDALLALPACVSPLHTPLSGDITSP 422

  Fly   837 QH---------SQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVTEGSI--PDDQKVAGLTGC 890
            .|         |.|:.|..|:......|...|..            ||.|:  |....:.|:.|.
 Frog   423 SHFPSPPSPVVSNAIDRISTSSSLPPPLPPPLPG------------TELSLPPPPPPPLPGMGGI 475

  Fly   891 N------------GAVSPPPAPP---MLKAIPPPPPP------MAP----------SMMPPPPPP 924
            :            |.:.|||.||   |...:||||||      |.|          .|:||||||
 Frog   476 SLTPPPPPPLPGMGGMLPPPPPPLPGMGGMLPPPPPPLPGMGGMLPPPPPPLPGMGGMLPPPPPP 540

  Fly   925 CP---GAPPPPPSMAQT--MAPAPP---------------KVD-----LPKK--NVPQPTNPLKS 962
            .|   |.|||||.:...  |.|.||               :||     |||.  .|.:||..:|.
 Frog   541 LPGMGGMPPPPPPLPGMGGMPPPPPPMFGMGTFTDEVVVARVDYSLGYLPKAYFKVNKPTLKMKK 605

  Fly   963 FNWSKLPDAKLQGT--VWSELDESKLYNNMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAK 1025
            .||.|||...:..|  :|:....|.........||::||...|                  ..||
 Frog   606 LNWQKLPPNVINDTHSMWASASSSNDTPEPNYSSIEQLFCLPQ------------------AVAK 652

  Fly  1026 Q---------KVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPS 1081
            :         |.:|.:|.::..|..|.|.:.|..:.|:.:.|...| ..:..:::::|.||..|.
 Frog   653 EPAAPVKKPPKEISFLDSKKNLNLNIFLKQFKCPNEEVIQLIEKGD-RSRFDIEILKQFLKLLPE 716

  Fly  1082 AEERALLDEHSEDIESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASR 1146
            ..|...|..:.||...|:.||:|...:..||.|:.|::.:...:...|..:.|.|:...|..|..
 Frog   717 KHEVENLKSYQEDKAKLSNADQFYLLLLGIPCYQLRIECMLICEEVNLMTDVLRPKAKVVSSACD 781

  Fly  1147 EVARSRRLRKLLELVLALGNYMNRGAR-GNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIER 1210
            ::..|.||....:|:|.:||::|.|:. |||:||::.:|.:|.:||::..: .||||::::.||:
 Frog   782 DIISSHRLPLFCQLILKVGNFLNYGSHTGNANGFKIGTLLKLTETKANQNR-ITLLHHILEEIEQ 845

  Fly  1211 KFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMRE 1275
            ...|||:|..|:.:|..|:.:::..|..:    .:|.....|:::...|:......|::...::|
 Frog   846 NHTDLLQLPSDLENVSTAAGINIENMYSE----TSGNLKKLRDLQNKISTAATDVKDQYEKSIQE 906

  Fly  1276 FHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRR 1340
                ......|:|::..|:..:..:......||.:.|..:|.|....:|...|.:|:.||:..:.
 Frog   907 ----CMDALKEVEEQLTDITQKKVKLADYLCEDSAKLSLEETFSTMKAFRDLFLKAKKDNKDRKE 967

  Fly  1341 RQEEEEKRAKQEAELKKRTIERKNKTG------------------LMTSVARNLGL-KSGSSNGD 1386
            :..:.|||.||.|:.:.:  .:|.:.|                  |:..:.:...| |:..:..:
 Frog   968 QAVKAEKRKKQLADEEAK--RQKGENGKIIRKGAAKLEEGCIIDALLADIKKGFQLRKTAKTKTE 1030

  Fly  1387 PDSPAK 1392
            .||..|
 Frog  1031 ADSCPK 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:461886	38/139 (27%)
		Drf_FH3	551..737	CDD:461885	60/189 (32%)
		Smc	<765..>875	CDD:440809	17/139 (12%)
		FH2	950..1328	CDD:396655	97/391 (25%)
inf2	NP_001072591.1	Drf_GBD	<16..152	CDD:461886	37/136 (27%)
		Drf_FH3	156..332	CDD:461885	59/186 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..391		7/50 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	440..541		30/112 (27%)
		FH2	595..955	CDD:418645	96/387 (25%)
		WH2	1001..1028	CDD:425359	3/26 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1026..1049		3/11 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1188..1244
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1260..1380