Protein Alignment DAAM and diaph1

DIOPT Version :9

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: XP_031754640.1
• Gene: diaph1 / 733754
• XenbaseID: XB-GENE-5995330
• Length: 1278
• Species: Xenopus tropicalis
• Alignment Length: 1241
• Identity: 326/1241 - (26%)
• Similarity: 542/1241 - (43%)
• Gaps: 254/1241 - (20%)

  Fly   347 TQPMPSVDELDTK-----FAELVEELDLT----APNKEAMLSLPAQKKWQIYCSRKLPLDAADGP 402
            :.|:.::.||:..     |.:::::::|.    .|.:|..:.:..:...|...:.|..:...:..
 Frog    80 SNPLQTLQELEDDVVLQLFEKMLDDMNLNPEKQQPLREKDIMIKREMVSQYLHTSKAGMSKKESS 144

  Fly   403 DAAAVTQPPTAEHYIERLKELVVHISLSPEDSPSHELGNRLDGHAAFVDALKTALRTSTHSFVLR 467
            .:|.:        ||:.||..:...||                 ...:::|:.:|..:..|:|..
 Frog   145 RSALM--------YIQDLKSGLGDNSL-----------------LLCLESLRVSLNNNPVSWVQN 184

  Fly   468 FVELDGLPALLDLLLQL--------DIRVANSPLHTSLIGCIKALMNNSMGRAHVLAHPTAIDTI 524
            | ..:||..||::|.::        |:|..:     .:|.|:||.|||:.|...:|.....|..:
 Frog   185 F-GAEGLSCLLEILKRIQDEQASLRDVRSEH-----EIIRCLKAFMNNNFGIKAMLGTEDGILLL 243

  Fly   525 ARSLAADNIRTKIAALEILGAVCLVP---GGHRKVLQAMLHFQVFATERT------RFQSIVNDL 580
            ||::........|.:|::|.|:|::|   ..|.:||:|:       |||.      ||:.:::.|
 Frog   244 ARAVDRSVPAMMIDSLKLLSALCILPQPEDMHERVLEAL-------TERAEMEEMERFKPLLDGL 301

  Fly   581 DRSTYAYRDNVNLKTALMSFVNAVLNYGPGQENLEFRLHLRYEFLMLGIQPVIDKLRTHENETLD 645
            :.::     .|.||.:.|..:|||::.|   |.|::|:|:|.|.:..|:..::.:||..|||.|.
 Frog   302 NIAS-----PVALKVSCMQLINAVISQG---EELDYRVHIRSELMRSGLAKLLKELRNTENEDLK 358

  Fly   646 RHLDFFEMVRAEDEKEFARRFKEEHVDTKSAGSMFELLRRKLSHSPAYPHMLSLLQHMLLL--PY 708
            ..|..|:.....|..:...|..:..::......:|::|...:..|.|.|..||:|||:||:  .|
 Frog   359 VQLGIFDEHSELDSDDLRGRLDDIRIEMDDFSDVFQVLLNTVKDSSAEPLFLSILQHLLLIRNDY 423

  Fly   709 TGHCTEHWLLIDRVVQQIVLQVEQRPNSDLIVDPDDPEKQLKLAAESPV-HDPDVAPLQIDVAKL 772
            ... .:::.|||.|:.||:||...       .|||...|.:.:..|:.: |..|...::...:|
 Frog   424 DAR-PQYYKLIDEVISQIILQKNG-------ADPDFKCKHVNIEIENLIDHFIDKKKVETSESK- 479

  Fly   773 VRLLVK--EEQLTQARKRADELERENFDVQSRLAK---KEQELDLRMQE----KEDLETGLARMR 828
            .|.|||  :.:||...:...|::.:..|.:.::.:   :::.||...||    |:.:||.|:::.
 Frog   480 ARDLVKKLDLELTARHELQVEMKAKESDFELKITELQGEKESLDAEKQEITADKQKMETELSQLV 544

  Fly   829 ERLEKESAQHSQAVQRAQTAEMRAEDLQHRLISEQQERARL-------------------ERLVT 874
            |::||.|.:     ..|...||.:......||........:                   ..|..
 Frog   545 EQVEKLSKE-----LEATKKEMASISTSAVLIPVPSASGNVPPPPPPPPPLPGATGIPPPPPLPG 604

  Fly   875 EGSIPDDQKVAG-------------------------------------------LTGCNGAVSP 896
            ...||....:.|                                           |.|.:|...|
 Frog   605 GSGIPPPPPLPGGSGIAPPLPAGFGIPPPPPLPGGFGIPPPPPLPGGSGIPPPPPLPGGSGIPPP 669

  Fly   897 PPAP-----------PMLKAIPPPPP-PMAPSM-----------MPPPPPPC------------- 925
            ||.|           |....|||||| |..|.:           :||||||.
 Frog   670 PPLPGGSGIPPPPPLPGGSGIPPPPPFPGGPGIPPPPPFPGGFGIPPPPPPFPGGPGIPPPPPFP 734

  Fly   926 --PGAPPPPPSMAQTMAP--------APPKVDL---PKKNVPQPTNPLKSFNWSKLPDAKL-QGT 976
              ||.|||||:....:.|        |||.:..   ||||. :|...||..||||:..|:| :.:
 Frog   735 GGPGVPPPPPAFGGGVPPPPGLGGWGAPPPLPFGLAPKKNY-KPEVQLKRPNWSKITPAELSEKS 798

  Fly   977 VWSELDESKLYNNMELESIDKLFSAYQKNGVS--ATDGSYEDLRVTGKAAKQKVLSVIDGRRAQN 1039
            .|::..|.:.........|...||:..|:..:  |.||   |.:...:..|.|.|.|:|.:.|||
 Frog   799 FWTQTKEDRFEKEELFAKITLTFSSQIKSSKAKKAEDG---DDKKAAQKKKTKELKVLDSKTAQN 860

  Fly  1040 CTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRF 1104
            .:|.|...:|...||...||.: :.|.|...||..|:|..|..::..:|.|...:.:.||..::|
 Frog   861 LSIFLGSFRMPYEEIKNVILQV-NEEVLTESMVSNLIKQLPEPDQLQMLTEFKNEYKDLAEPEQF 924

  Fly  1105 LYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMN 1169
            ...:..:|....||.::.:|..|...|.::.|.|.||..|..||.:.:....|||:.|.:||:||
 Frog   925 GVVMCSVPRLRPRLNAILFKLLFNEQIENIKPDIVSVTAACEEVQKCQSFASLLEITLLVGNFMN 989

  Fly  1170 RGAR-GNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSL 1233
            .|:| .:|.||.::.|.:|.||||:..| |||||:||:..|..:.|:||..|::.||.:||:||.
 Frog   990 AGSRNADAYGFDISFLCKLKDTKSADQK-TTLLHFLVETCENDYPDVLKFPDEMVHVEKASRVSA 1053

  Fly  1234 GEMDKDIQMLRTGLADVAREIEFHRSSGPAQ-QGDRFLPVMREFHAQASVRFAELEDKFQDMKTR 1297
            ..:.|::..::..:||:.|:|:   |..|.: :.|:|:..|..|..:|..::.:|....::|.:.
 Frog  1054 ETLQKNLDQMKKQIADLQRDID---SFPPTEDEKDKFVEKMTIFVKEAQEQYTKLCMMHENMLSL 1115

  Fly  1298 FDRAVRLFGEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKR---AKQEAELKKRT 1359
            |....:.|..|......:|||....:|...|..|..:|:. ||..||:.||   ||::|| |:|.
 Frog  1116 FQDLGKYFVFDPKKTSIEEFFADLQNFRNMFLHALKENQK-RREAEEKMKRAKLAKEKAE-KERL 1178

  Fly  1360 IERKNKTGLMTSVARNLGLKSGSSNGDPDSPAKGGDNKGEFDDLISALRTGDVFGEDMAKFKRSR 1424
            .:::.|..|:...|.                   ||..|..|.|:.||.:|       |.|:|.|
 Frog  1179 EKQQKKEQLIDMNAE-------------------GDETGVMDSLLEALNSG-------AAFRRKR 1217

  Fly  1425 KARVLN 1430
            ..|..|
 Frog  1218 GPRQAN 1223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920	44/215 (20%)
		Drf_FH3	551..737	CDD:283917	56/193 (29%)
		FliJ	779..>875	CDD:280262	22/121 (18%)
		FH2	950..1328	CDD:280362	121/382 (32%)
diaph1	XP_031754640.1	Drf_GBD	86..267	CDD:399398	43/211 (20%)
		Drf_FH3	273..463	CDD:368862	61/212 (29%)
		SMC_prok_B	<456..>565	CDD:274008	27/114 (24%)
		FH2	771..1146	CDD:396655	122/383 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010