Protein Alignment DAAM and Inf2

DIOPT Version :9

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: XP_030102765.1
• Gene: Inf2 / 70435
• MGIID: 1917685
• Length: 1285
• Species: Mus musculus
• Alignment Length: 1173
• Identity: 270/1173 - (23%)
• Similarity: 488/1173 - (41%)
• Gaps: 257/1173 - (21%)

  Fly   382 AQKKWQIYCSRKLPLDAADGPDAAAVTQPPTAEHYIERLKELVVHISLSPEDSPSHELGNRLDGH 446
            ||:||.....:..|.|:           .||..:......||.:.:...|.
Mouse     7 AQRKWAALKEKLGPQDS-----------DPTEANLESAEPELCIRLLQMPS-------------- 46

  Fly   447 AAFVDALKTALRTSTHSFVLRFVELDGLPALLDLLLQLD----IRVANSPLHTSLIGCIKALMNN 507
            ......|:..|.:|...::::|:|..||..||:.|.:|.    .|::::.|..:.|.|::|:||:
Mouse    47 VVNYSGLRKRLESSDGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCISCVRAVMNS 111

  Fly   508 SMGRAHVLAHPTAIDTIARSLAADNIRTKIAALEILGAVCLV-PGGHRKVLQAMLHFQVFATERT 571
            ..|..::|::...:..::::|...|:..|....|:|.|:|:. |.||...|.|:.|:::..:::.
Mouse   112 QQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHALTLDALDHYKMVCSQQY 176

  Fly   572 RFQSIVNDLDRSTYAYRDNVNLKTALMSFVNAVLNYGPGQENLEFRLHLRYEFLMLGIQPVIDKL 636
            ||..|:::|..|     |||.....|:|.:||:: .||  |:|..|..||.||:.|.:..::.:|
Mouse   177 RFSVIMSELSDS-----DNVPYVVTLLSVINAII-LGP--EDLRSRAQLRSEFIGLQLLDILTRL 233

  Fly   637 RTHENETLDRHLDFFEMVRAEDEKEFARRFKEEHVDTKSAGSMFELLRRKLSHSPAYPHMLSLLQ 701
            |..|:..|...|:.||..:||||:|..|  ..:.::..|...:|..|..|:|.|||...:||:||
Mouse   234 RDLEDADLLIQLEAFEEAKAEDEEELQR--ISDGINMNSHQEVFASLFHKVSCSPASAQLLSVLQ 296

  Fly   702 HMLLLPYTGHCTE-HWLLIDRVVQQIVLQVEQRPNSDLIVDPDDPEKQLKLAAESPVHDPDVAPL 765
            .::.|...|...: .|..::.:|.:.||                      ||:     |.....|
Mouse   297 GLMHLEPAGRSGQLLWEALENLVNRAVL----------------------LAS-----DAQACTL 334

  Fly   766 QIDVAKLVRLLVKEEQLTQARKRADELERENFDVQSRLAKKEQELDLRMQEKEDLETGLARMRER 830
            :..|.:|:.:        :.|.|...|::.:..||:...:.:..    ..:.....|.....::.
Mouse   335 EEVVERLLSI--------KGRPRPSPLDKAHKSVQTNSVQNQGS----SSQNTTTPTTKVEGQQP 387

  Fly   831 LEKESAQHSQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVTEGSIPDDQKVAG--------- 886
            :.....||..::|.:..      |:..:.::       ||:.:|...:|.....:.
Mouse   388 VVASPCQHVGSIQSSSV------DIAPQPVA-------LEQCITALPLPTPPLSSSTPVLPPTPP 439

  Fly   887 ---------------------LTGCNGAVSPPPAPP-------------MLKAIPPPPPPMAP-- 915
                                 |.| :|..||||.||             .:...||||||..|
Mouse   440 PLPGPGATSPLPPPPPPLPPPLPG-SGTTSPPPPPPPPPPLPPPLPGSGTISPPPPPPPPPLPGT 503

  Fly   916 -SMMPPPPPPCPGAP------PPPPSMAQTMAPAPPKVDLPK----------------------- 950
             ::.||||||.|..|      ||||.....|.|.||...||:
Mouse   504 GAVSPPPPPPLPSLPDSHKTQPPPPPPLPGMCPVPPPPPLPRAGQIPPPPPLPGFSVPSMMGGVE 568

  Fly   951 -------------------KNVPQPTNPLKSFNWSKLPD--AKLQGTVWSEL-DESKLYNNMELE 993
                               :.|..||..:|..||.|||.  |:.:.::|:.| .........:..
Mouse   569 EIIVAQVDHSLGSAWVPSHRRVNPPTLRMKKLNWQKLPSNVARERNSMWATLGSPCTAAVEPDFS 633

  Fly   994 SIDKLFS---AYQKNGVSATDGSYEDLRVTGKAAKQ-KVLSVIDGRRAQNCTILLSKLKMSDMEI 1054
            ||::|||   |..|...:|            .|.|: |.::.:|.:::.|..|.|.:.|.|:.|:
Mouse   634 SIEQLFSFPTAKPKEPSAA------------PARKEPKEVTFLDSKKSLNLNIFLKQFKCSNEEV 686

  Fly  1055 SKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRFLYEISKIPHYEQRLK 1119
            :..|.:.|:: :..:::::||||..|...|...|...:|:...|:.||:|...:..||.|..|::
Mouse   687 TSMIQAGDTS-KFDVEVLKQLLKLLPEKHEIENLRAFTEERAKLSNADQFYVLLLDIPCYPLRVE 750

  Fly  1120 SLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGAR-GNASGFRLAS 1183
            .:...:...:.::.:.|:...|:.|...:..|:||....:|:|.:||::|.|:. |:|.||::::
Mouse   751 CMMLCEGTAIVLDMVRPKAQLVLTACESLLTSQRLPVFCQLILKIGNFLNYGSHTGDADGFKIST 815

  Fly  1184 LNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLA 1248
            |.:|.:|||..:: .||||::::.:|:...|||:|..|:....:|:.:::..:..:.......|.
Mouse   816 LLKLTETKSQQSR-VTLLHHVLEEVEKSHPDLLQLSRDLEPPSQAAGINVEIIHSEASANLKKLL 879

  Fly  1249 DVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFA-ELEDKFQDMKTRFDRAVRLFGEDGSVL 1312
            :..|::.........|..:|.         |||:..: ||:..|..::.:.........||...|
Mouse   880 EAERKVSASIPEVQKQYAERL---------QASIEASQELDKVFDAIEQKKLELADYLCEDPQQL 935

  Fly  1313 QPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQEAELKKRTIERKNKTGLMTSVARNLG 1377
            ..::.|....:|...|..|..:|:..:.:..:.|:|.:|.||.:.|  ..:::.|
Mouse   936 SLEDTFSTMKTFRDLFTRALKENKDRKEQMAKAERRKQQLAEEEAR--RPRDEDG---------- 988

  Fly  1378 LKSGSSNGDPDSPAKGGDNKGE----FDDLISALRTGDVFGEDMAKFKRSRKARVLNGGGSSTGH 1438
                       .|.:.|..|.|    .|.|::.:|.|         |:..:.||. .|...::|.
Mouse   989 -----------KPIRKGPGKQEEVCVIDALLADIRKG---------FQLRKTARG-RGDTEASGR 1032

  Fly  1439 TSP 1441
            .:|
Mouse  1033 VAP 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920	37/169 (22%)
		Drf_FH3	551..737	CDD:283917	58/186 (31%)
		FliJ	779..>875	CDD:280262	12/95 (13%)
		FH2	950..1328	CDD:280362	95/428 (22%)
Inf2	XP_030102765.1	Drf_GBD	<14..152	CDD:368864	33/162 (20%)
		Drf_FH3	156..341	CDD:368862	63/221 (29%)
		FH2	587..951	CDD:388631	95/386 (25%)
		WH2	1005..1020	CDD:128542	5/23 (22%)
		PHA03307	1034..>1278	CDD:223039	1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3069
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850