Protein Alignment DAAM and grid2ipa

DIOPT Version :9

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: XP_009297619.1
• Gene: grid2ipa / 561017
• ZFINID: ZDB-GENE-091113-42
• Length: 1804
• Species: Danio rerio
• Alignment Length: 1106
• Identity: 242/1106 - (21%)
• Similarity: 421/1106 - (38%)
• Gaps: 309/1106 - (27%)

  Fly   324 FKDDEPPEICVVEGA-----FTLQTLTPTQPMPSVDELDTKFAELVEELDLTAPNKEAMLSLPAQ 383
            |.|..||.....|.|     |......|..|.|..:....:     :.:....|.::.::|  .|
Zfish   922 FNDPPPPAGFTPEHAPRQLTFRRHPGPPPPPPPRANPPPKR-----QSIHKVLPTRDELMS--QQ 979

  Fly   384 KKWQIYCSRKLPLDAADGPDAAAVTQPPTAEHYIERLKELVVHISLSPEDSPSHELG-NRLDGHA 447
            :..|.:.|  ||:.             |||.|..:..:::  |.||.|  .||.|:. ..:.|||
Zfish   980 QLLQEHHS--LPVQ-------------PTAGHPQQSQQQM--HQSLPP--MPSPEINQTSISGHA 1025

  Fly   448 AFVDALKTALRTSTHSFVLRFVELDGLPALLDLLLQLDIRVANSPLHTSLIGCIKALMNNSMGRA 512
            .:      .:::..|                             |.|
Zfish  1026 IY------EMQSQVH-----------------------------PAH------------------ 1037

  Fly   513 HVLAHPTAIDTIARSLAADNIRTKIAALEILGAVCLVPGGHRKVLQAMLHFQVFATERTRFQSIV 577
            .|..||        .:..|:                           .:| |....:|.:.|||
Zfish  1038 QVHQHP--------QMQQDH---------------------------QMH-QFHQHKRHQSQSI- 1065

  Fly   578 NDLDRSTYAYRDNVNLKTALMSFVN-----------AVLNYGPGQENLEFRLHLRYEFLMLGIQP 631
                :..:::|.:..::|.|.|.::           .:....|...:.:.::|..||
Zfish  1066 ----KVHHSHRSHQPIQTQLSSSMDRLDRIDRNPDRLIYEMQPQPLHSDQQVHHAYE-------- 1118

  Fly   632 VIDKLRTHENETLDR--------HLDFFE-MVRAEDEKEFARRFKEEHVDTKSAGSM-------- 679
            :....:.|...::||        ||:..| |.|.|..:...|:....|:....:.::
Zfish  1119 MHQSHQAHLTSSMDRLDRLEQIQHLERLERMERIERLERADRQMHRAHMAQALSQAVQPPQQSQQ 1183

  Fly   680 ------FELLRRKLSHSPAYPHMLSLLQHMLLLPYTGHCTEHWLLIDRVVQQIVLQVEQRPNSDL 738
                  :::.:....:.|..|.           |.|.|..:    |:.:.|  |..::..|....
Zfish  1184 QYNQQQYQMHQSNQDYPPTQPP-----------PPTRHIHQ----IEHIHQ--VQPIQSAPQYHQ 1231

  Fly   739 IVDPDDPEKQLKLAAESPVHDPDVAPLQIDVAKLVRLL--VKEEQLTQARKRADELERENFDVQS 801
            |..|..|.:..::.:   ...|..:.||.....|.:.|  .:::||.|.::|..:.:.:..:.|.
Zfish  1232 IHQPHQPHQTQQILS---TFQPHPSQLQQQQQLLQQQLQQQQQQQLQQQQQRQQQQQLQQLEQQQ 1293

  Fly   802 RLAKKEQELDLRMQEKEDLETGLARMRERLEKESAQHSQAVQRAQTAEMRAEDLQHRLISEQQER 866
            :|.:.||:..|:.|:              ::::.||..|.:|:.|         |||
Zfish  1294 QLQQLEQQQQLQQQQ--------------IQQQQAQQQQQIQQQQ---------QHR-------- 1327

  Fly   867 ARLERLVTEGSIPDDQKVAGLTGCNGAVSPPP---------------------APPMLKAIPPPP 910
                      |.|....||     ....||.|                     .||    |.|.|
Zfish  1328 ----------STPQIPSVA-----QARQSPQPMYHEHRHHHHHRSHHEAQSQMQPP----ISPQP 1373

  Fly   911 ----PPMAPSMMPPPPPPCPGAPP--PPPSMAQTMAPAPPKVDLPKKNVPQPTN----PLKSFNW 965
                |....|:.||||||.|  ||  |||              |||.: ||.::    .:|...|
Zfish  1374 QTHNPTEGSSVEPPPPPPLP--PPCVPPP--------------LPKGS-PQKSDSSHMSVKRLRW 1421

  Fly   966 SKLPDAKLQGTVWSELDESKLYNNME--LESID-KLFSAYQKNGVSATDGS--YEDLRVTGKAAK 1025
            .::.::  :||:|.:::|...|:.:.  ::.:| :|....||..|:..:.|  .|..:      |
Zfish  1422 EQVENS--EGTIWGQMEEDSDYDKLSDMVKYLDLELHFGTQKTPVALPEPSPQVETFK------K 1478

  Fly  1026 QKVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDE 1090
            :.|:.::..::|.|.:||::.||:|..|:.:.:::| |:|:|:...::|||.:.|..:|....::
Zfish  1479 KDVVEILSHKKAYNASILIAHLKLSPGELRQVLMTM-SSERLEPPHIKQLLLYAPDDDEVRQYEQ 1542

  Fly  1091 HSEDIESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLR 1155
            :..|...|:..|:|:.::..:|.|:.||||||:|........::......|.:||.|:..|::|.
Zfish  1543 YRNDPGKLSEPDQFVLQMLSVPEYKTRLKSLHFKTTLQEKTEEMRGAYDCVFKASLELKNSKKLA 1607

  Fly  1156 KLLELVLALGNYMNRG--ARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKL 1218
            |:||.|||:|||:|.|  ..|..:||::..|..|:.||:...| :|.||.||:.:.:.|.::|..
Zfish  1608 KILEFVLAMGNYLNNGQPKTGKTTGFKINFLTELSTTKTVDGK-STFLHILVKSLCQHFPEVLDF 1671

  Fly  1219 EDDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVR 1283
            ..::..|.:|:||:...:..|...|...:.|:....:    ..||...|||..||..|...:...
Zfish  1672 GKELVMVPQAAKVNQRNITSDFNDLHATIQDIRVACQ----KMPATAEDRFAVVMSGFLENSHPA 1732

  Fly  1284 FAELEDKFQDMKTRFDRAVRLFGEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKR 1348
            ...||...|.....|.:....|||||.....:.|||||..|:|.|.....|.::....:.....|
Zfish  1733 VQSLESLQQRAMEEFCKVASYFGEDGKTTTTENFFGIFAEFIAKFERTLSDIQTENPPRSPRSPR 1797

  Fly  1349 A 1349
            |
Zfish  1798 A 1798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920	30/199 (15%)
		Drf_FH3	551..737	CDD:283917	34/219 (16%)
		FliJ	779..>875	CDD:280262	18/95 (19%)
		FH2	950..1328	CDD:280362	112/388 (29%)
grid2ipa	XP_009297619.1	PDZ_signaling	56..121	CDD:238492
		PDZ_signaling	135..203	CDD:238492
		HN_L-delphilin-R1_like	230..309	CDD:259820
		PDZ_signaling	384..459	CDD:238492
		HN_L-delphilin-R2_like	498..577	CDD:259821
		BAF1_ABF1	<1014..1171	CDD:282530	36/258 (14%)
		FH2	1406..1778	CDD:280362	111/385 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45725
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010