Protein Alignment DAAM and daam1a

DIOPT Version :9

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: XP_017207260.1
• Gene: daam1a / 557451
• ZFINID: ZDB-GENE-030911-6
• Length: 1069
• Species: Danio rerio
• Alignment Length: 1163
• Identity: 566/1163 - (48%)
• Similarity: 770/1163 - (66%)
• Gaps: 121/1163 - (10%)

  Fly   313 GFRGRRVWCGCFKDDEPPEI--CVVEGA-FTLQTLTPTQPMPSVDELDTKFAELVEELDLTAPNK 374
            |.||....|.|.|..:.|||  .:..|: |||||:.||.|||..:|||..|.|||:|||||..::
Zfish     8 GGRGLSFLCCCLKGSDHPEITYSLRHGSNFTLQTMEPTLPMPPTEELDAMFTELVDELDLTEKHR 72

  Fly   375 EAMLSLPAQKKWQIYCSRKLPLDAADGPDAAAVTQPPTAEHYIERLKELVVHISLSPEDSPSHEL 439
            .||.:|||:||||||||:|...:...|    |.:.|   |.||:::..:....||...:....|.
Zfish    73 AAMFALPAEKKWQIYCSKKKEQEENKG----ATSWP---EFYIDQINSMAARKSLLALEKEDEEE 130

  Fly   440 GNRLDGHAAFVDALKTALRTSTHSFVLRFVELDGLPALLDLLLQLDIRVANSPLHTSLIGCIKAL 504
            .|:.      :::|||||||....||.||::.|||..:|:.|..:|.....|.:|||||||||||
Zfish   131 RNKT------IESLKTALRTQPMRFVTRFIDQDGLTCILNFLKTMDYETTESQIHTSLIGCIKAL 189

  Fly   505 MNNSMGRAHVLAHPTAIDTIARSLAADNIRTKIAALEILGAVCLVPGGHRKVLQAMLHFQVFATE 569
            ||||.||||||:|..:|:.||:|||.:||:||:|.|||:||||||||||:|:|:||||:|.||.|
Zfish   190 MNNSQGRAHVLSHSESINIIAQSLATENIKTKVAVLEIMGAVCLVPGGHKKILEAMLHYQKFACE 254

  Fly   570 RTRFQSIVNDLDRSTYAYRDNVNLKTALMSFVNAVLNYGPGQENLEFRLHLRYEFLMLGIQPVID 634
            |||||:::|||||||..|||.||||||:|||:||||:.|.|:.:||||:||||||||||||||||
Zfish   255 RTRFQTLLNDLDRSTGRYRDEVNLKTAIMSFINAVLSQGAGETSLEFRIHLRYEFLMLGIQPVID 319

  Fly   635 KLRTHENETLDRHLDFFEMVRAEDEKEFARRFKEEHVDTKSAGSMFELLRRKLSHSPAYPHMLSL 699
            |||:|||.|||||||||||:|.|||...|:||:..|||||||..||||:|::::|:.|:||.:|:
Zfish   320 KLRSHENSTLDRHLDFFEMLRNEDELALAKRFENVHVDTKSATQMFELIRKRINHTDAFPHFISV 384

  Fly   700 LQHMLLLPY--TGHCTEHWLLIDRVVQQIVLQVEQRPNSDLIVDPDDPEKQLKLAAESPVHDPDV 762
            |||.|.:||  ||:..::|:|:||:||||:||               .:|.|         ||||
Zfish   385 LQHCLHMPYKKTGNTVQYWVLLDRIVQQIILQ---------------NDKGL---------DPDV 425

  Fly   763 APLQ-IDVAKLVRLLVKEEQLTQARKRADELERENFDVQSRLAKKEQELDLRMQEKEDLETGLAR 826
            |||: .||..:||:||.|.::.|.:::|:::.:|:.::|.:|.|||:|.|.:.||||::...|.:
Zfish   426 APLENFDVKNVVRMLVNENEVKQWKEQAEKMRKEHNELQQKLEKKERECDAKAQEKEEMMQTLNK 490

  Fly   827 MRERLEKESAQHSQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVTEGSIPDDQKVAGLTGCN 891
            |:|:|||||::|....|  |.|::               .|||..:....:||....:|.|   .
Zfish   491 MKEKLEKESSEHKLVKQ--QVADL---------------SARLHEMSNRTNIPGGPPLAPL---G 535

  Fly   892 GAVSPPPAPPMLKAIPPPPPPMAPSMMPPPPPPCPGAPPPPPSMAQTMAPAPP----KVDLPKKN 952
            ..:.|||.||....:|||||   |...||||||.||.|||||.:....||.||    ...|.|||
Zfish   536 PGLPPPPPPPGQAGLPPPPP---PGGAPPPPPPPPGGPPPPPGLLGFGAPPPPGGLLGSTLKKKN 597

  Fly   953 VPQPTNPLKSFNWSKLPDAKLQGTVWSELDESKLYNNMELESIDKLFSAYQK------NGVSATD 1011
            :|||:||||||||:||.:.||:||||.:||:.:::..::||.|:|.|||||:      |.....:
Zfish   598 IPQPSNPLKSFNWTKLSENKLEGTVWLDLDDVRVFKQLDLEDIEKTFSAYQRQQDFLFNNFRQKE 662

  Fly  1012 GSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLL 1076
            .  ||..||.|  |.|.||||||||||||.|||||||:|:.||.:|||:||..|.|..||:||||
Zfish   663 S--EDDTVTSK--KVKELSVIDGRRAQNCNILLSKLKLSNEEIKRAILTMDEQEDLPKDMLEQLL 723

  Fly  1077 KFTPSAEERALLDEHSEDIESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSV 1141
            ||.|...:..||:||..::|.:|:|||||||:|:|.||:|||:||::||:|...|.::.|::.::
Zfish   724 KFVPEKSDVDLLEEHKHELERMAKADRFLYEMSRINHYQQRLQSLYFKKKFAERIAEIKPKVEAL 788

  Fly  1142 MEASREVARSRRLRKLLELVLALGNYMNRGARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQ 1206
            .:||:||.:|:.||:|||:|||.|||||:|.||||.||:::|||::||||||..|..||||||:.
Zfish   789 SKASKEVLQSKNLRQLLEIVLAFGNYMNKGQRGNAYGFKVSSLNKIADTKSSIDKNVTLLHYLIT 853

  Fly  1207 VIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLP 1271
            |:|:|:..:..:.:|:.:|..|:||::.|::|||..||:||..|..|:|:.|:. |...||:|:.
Zfish   854 VLEQKYPKVSLIHEDLQNVPVAAKVNMTELEKDINNLRSGLKSVETELEYQRTQ-PQTYGDKFVS 917

  Fly  1272 VMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGSVLQPDEFFGIFDSFLAAFAEARHDNE 1336
            |:.:|...|...|:::||..||.|..|.:||:.||||.:.:||||||||||.||..|:||:.|||
Zfish   918 VVSQFITVAGFSFSDIEDSLQDAKDSFGKAVQHFGEDATRMQPDEFFGIFDQFLQGFSEAKQDNE 982

  Fly  1337 SFRRRQEEEEKRAKQEAELKKRTIERKNKTGLMTSVARNLGLKSGSSNGDPDSPAKGGDNKGEFD 1401
            :.|||:||||:||:.||:||::. ||:.|:            :....|.:.|         ||||
Zfish   983 NMRRRKEEEERRARMEAQLKEQR-ERERKS------------RKAKENCEED---------GEFD 1025

  Fly  1402 DLISALRTGDVFGEDMAKFKRSRKARVLNGGGSSTGHTSPPRHGSLQREESGRERERT 1459
            ||:||||:|:||.:||:|.|.:||..|.:..                  ||.|||..|
Zfish  1026 DLVSALRSGEVFDKDMSKMKHNRKRPVKSSA------------------ESSRERPVT 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920	96/198 (48%)
		Drf_FH3	551..737	CDD:283917	122/187 (65%)
		FliJ	779..>875	CDD:280262	30/95 (32%)
		FH2	950..1328	CDD:280362	199/383 (52%)
daam1a	XP_017207260.1	Drf_GBD	46..233	CDD:283920	96/199 (48%)
		Drf_FH3	236..440	CDD:283917	135/227 (59%)
		DUF342	<447..525	CDD:302792	29/94 (31%)
		FH2	595..975	CDD:280362	199/384 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595477
Domainoid	1	1.000	397	1.000	Domainoid score	I718
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1041	1.000	Inparanoid score	I261
OMA	1	1.010	-	-		QHG54599
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	1	1.000	-	-		otm24824
orthoMCL	1	0.900	-	-		OOG6_102298
Panther	1	1.100	-	-	O	PTHR45725
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1795
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.910