DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DAAM and diaph3

DIOPT Version :9

Sequence 1:	NP_001188522.1	Gene:	DAAM / 31075	FlyBaseID:	FBgn0025641	Length:	1463	Species:	Drosophila melanogaster
Sequence 2:	NP_001003624.1	Gene:	diaph3 / 445230	ZFINID:	ZDB-GENE-040801-144	Length:	267	Species:	Danio rerio

Alignment Length:	313	Identity:	63/313 - (20%)
Similarity:	105/313 - (33%)	Gaps:	114/313 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 GGSDQQQSQSNHENGLGSEAGSFYTHNILGYTFGYPFGLKEDLDGSGNCNSNCNGSSNTNGLGLR 285
            |.|..::::.|.:.|.|:..                              |:..|||..:|....
Zfish    11 GSSQGRENKFNRKKGFGAGV------------------------------SSQGGSSGDDGEKKP 45

  Fly   286 KWLSGNTSSNETPLQKHYR----HQQKKKMPGFRGRRVWCGCFKDDEPPEICVVEGAFTLQTLTP 346
            |:|. ..||...|..|..|    |..|....|     .|....:.:|                 .
Zfish    46 KFLD-RFSSIRIPGSKKERPNLSHMSKHSSSG-----DWSSSSEFEE-----------------L 87

  Fly   347 TQPMPSVDELDTKFAELVEELDLTAPNKEAMLSLPAQKKWQIYCSRKLPLDAADGPDAAAVTQPP 411
            :..:.|..|:...|.:::|:::|   |:|                :|.||...|
Zfish    88 SSRITSEKEILALFEKMMEDMNL---NEE----------------KKAPLREKD----------- 122

  Fly   412 TAEHYIERLKELVVH----------ISLSPEDSPSHELGNRLDGHA-----AFVDALKTALRTST 461
                 :...:|:|:.          :..|.:.||...|.....|..     |.:|:|:.:|.::.
Zfish   123 -----LNTKREMVLQYIVTAAKTGSLRSSSQISPQEFLSELKSGATDERLFACLDSLRVSLTSNP 182

  Fly   462 HSFVLRFVELDGLPALLDLLLQLDI-----RVANSPLHTSLIGCIKALMNNSM 509
            .|:|..|.. :||..|||.|.:|.:     :|.....| .:|.|:||.|||.:
Zfish   183 VSWVQSFGH-EGLGLLLDTLEKLLLKKHQEKVDKKSQH-KVIQCLKAFMNNKV 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920	41/181 (23%)
		Drf_FH3	551..737	CDD:283917
		FliJ	779..>875	CDD:280262
		FH2	950..1328	CDD:280362
diaph3	NP_001003624.1	Drf_GBD	93..>233	CDD:283920	41/176 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3069
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950