DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DAAM and AT5G07740

DIOPT Version :9

Sequence 1:	NP_001188522.1	Gene:	DAAM / 31075	FlyBaseID:	FBgn0025641	Length:	1463	Species:	Drosophila melanogaster
Sequence 2:	NP_001331227.1	Gene:	AT5G07740 / 3770686	AraportID:	AT5G07740	Length:	1683	Species:	Arabidopsis thaliana

Alignment Length:	544	Identity:	167/544 - (30%)
Similarity:	266/544 - (48%)	Gaps:	93/544 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   892 GAVSPPPAPPML-KAIPPPPPPMAPSMMPPPPPP---CPGAPPPPPSMAQTMAPAPPKVDLPK-- 950
            |...|||.|||. .|.|||||||.....||||||   .||||||||... ..||.||....|:
plant  1141 GGAPPPPPPPMHGGAPPPPPPPMRGGAPPPPPPPGGRGPGAPPPPPPPG-GRAPGPPPPPGPRPP 1204

  Fly   951 -------------------------KNVPQP--------TNPLKSFNWSKLPDAKLQGTVWSELD 982
                                     :.:|:|        .:.||..:|.|:..| |||::|.||.
plant  1205 GGGPPPPPMLGARGAAVDPRGAGRGRGLPRPGFGSAAQKKSSLKPLHWVKVTRA-LQGSLWDELQ 1268

  Fly   983 ---ESKLYNNMELESIDKLFSA-YQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTIL 1043
               ||:..:..::..|:.|||| .||    ..|.|....:..|  ||.:.:.:||.|||.|..|:
plant  1269 RHGESQTPSEFDVSEIETLFSATVQK----PADKSGSRRKSVG--AKPEKVQLIDLRRANNTEIM 1327

  Fly  1044 LSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRFLYEI 1108
            |:|:||...::..|:|:||.: .|.:|.:|.|:||.|:.||..||..::.|..:|.:.:::..|:
plant  1328 LTKVKMPLPDMMAAVLAMDES-VLDVDQIENLIKFCPTKEEMELLKNYTGDKTTLGKCEQYFLEL 1391

  Fly  1109 SKIPHYEQRLKSLHYKKRFMLTI--NDLVP--------------------------------RIT 1139
            .|:|..|.:|:...:|.:|...:  |.|:|                                .:.
plant  1392 MKVPRVEAKLRVFSFKFQFGTQVWWNYLIPLFSVYLILWRTKYNFIRLLIMMFFVQITEFKKSLN 1456

  Fly  1140 SVMEASREVARSRRLRKLLELVLALGNYMNRG-ARGNASGFRLASLNRLADTKSSAAKGTTLLHY 1203
            :|..|..||..|::|:::::.:|.|||.:|:| |||.|.||:|.||::|:||:::.:| .||:||
plant  1457 AVNSACEEVRSSQKLKEIMKKILYLGNTLNQGTARGAAVGFKLDSLSKLSDTRAANSK-MTLMHY 1520

  Fly  1204 LVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDR 1268
            |.:|:..|...||....|:..:..|||:.|..:.:::|.:..||..:.:|:....|.||.  .|.
plant  1521 LCKVLASKASVLLDFPKDLESLESASKIQLKSLAEEMQAIIKGLEKLNQELTASESDGPV--SDV 1583

  Fly  1269 FLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGSVLQPDEFFGIFDSFLAAFAEARH 1333
            |...:.:|.:.|....|.:...:..:....|.....||||.:....::......:|:..|.:|..
plant  1584 FRKTLGDFISVAETEVATVSSLYSVVGRNADALAHYFGEDPNRCPFEQVTATLLNFIRLFKKAHE 1648

  Fly  1334 DNESFRRRQEEEEKRAKQEAELKK 1357
            :|.   ::.|.|:|:|.:|||::|
plant  1649 ENV---KQAELEKKKALKEAEMEK 1669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920
		Drf_FH3	551..737	CDD:283917
		FliJ	779..>875	CDD:280262
		FH2	950..1328	CDD:280362	122/451 (27%)
AT5G07740	NP_001331227.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	185	1.000	Domainoid score	I993
eggNOG	1	0.900	-	-		E1_KOG1922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	1	1.000	-	-		otm2452
orthoMCL	1	0.900	-	-		OOG6_102298
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.720