Protein Alignment DAAM and capu

DIOPT Version :10

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Alignment Length: 1579
• Identity: 316/1579 - (20%)
• Similarity: 536/1579 - (33%)
• Gaps: 499/1579 - (31%)

  Fly    53 APSGGASTSVTSLNGSCIAINGGIGEGATATASAATSTAAGVTKITITSDNGNGNASTS-TKAPT 116
            :|.||||.....:.|     .||.||...|.:....|....::::.     |......: ..:|.
  Fly    15 SPPGGASLVRMGITG-----GGGAGEVGVALSERRGSRVRVLSRLM-----GQKRIREAFLHSPK 69

  Fly   117 TGSSIDGYKNSSLVSITSL-NSCSDLSQGSTATLPISSNSCSGNNVSRHPLSNNNSGSDTSSNNF 180
            .||       ||.|::... |..||.....| .:......||......|         |..|.:.
  Fly    70 LGS-------SSEVNLQGAGNGSSDWIAAET-EVEHGQLDCSAEPADFH---------DVVSLDC 117

  Fly   181 QERFDFEHWKGLLSDYNCFHGLYRYWTQCSGRSSSANDNGGGSDQQQSQSNHENGLGSEAGSFYT 245
            .:..::         :||..      .:|...|:.........:.||.|..|.:      ...:.
  Fly   118 TDSLEY---------HNCSS------DECCYASNDTLTERQNRELQQRQRQHHH------HHHHI 161

  Fly   246 HNILGYTFGYPFGLKEDLDGSGNCNS-NCNGSSNTNGLGLRKWLSGNTSSNETPLQKHYRHQQKK 309
            ||.......||:      |....|.| :.|.|..|:.:            :|..:.|||.:...|
  Fly   162 HNAHESHHHYPY------DRRSLCTSCSSNDSLFTDPV------------DELIISKHYLNTAAK 208

  Fly   310 KMPGFRGRRVWCGCFKDDEP-PEICVVEGAFTLQTLTP--------------------------- 346
            :....:.:|        |.| .||.|.    ::.||:|
  Fly   209 EHNNPKAKR--------DRPLSEISVT----SVDTLSPNTAKAVLELQKRCRADKLACLSLTRVT 261

  Fly   347 ----TQPMPSVDELDTKFAELVEELD-LTAPNK-------EAMLSLPAQKK-------------- 385
                ...:..|:|.|.  |.::.:.| |.|||.       |.:::|...||
  Fly   262 YLSIANDLQEVEEPDR--ASILHDTDLLVAPNSPAESSPDEELMALQLGKKLAQVLGSGAGSPLT 324

  Fly   386 --------------------WQIYCSRKLPLDAADGPDAAAVTQPPTAEHYIERLKELVVHISLS 430
                                :.:..::|:.|........|||||.|...            .|.:
  Fly   325 PGTMEPCAAGSGSPLANGELFNVSKAKKVELQNLSSRFTAAVTQTPPGV------------TSST 377

  Fly   431 PEDS----PSHELG-----NRLDGHAAFVDALK---TALRTSTHSFVLRFVELDGLPALL----- 478
            |.:|    |:..||     ..|:..:..:.:.|   |.:::.|:|.....||.|..|..|
  Fly   378 PNESGVTGPAGPLGATTSSPSLETQSTVIISFKSSQTPVQSQTNSAASENVEDDTAPLPLPPPPP 442

  Fly   479 ------DLLLQLDI--RVANSPLHTSLIGCIKALMNNSMGRAHVLAHPTAIDT------IARSLA 529
                  ..||..::  :||:..:..|..|      |||....::.  ||:.:|      .:.||.
  Fly   443 GFGTPTTPLLSSNVLKKVASFTVEKSSAG------NNSSNPPNLC--PTSDETTLLATPCSSSLT 499

  Fly   530 ADNIRTKIAALEILGAVCLVPGGHRKVLQAMLHFQVFATERTRFQSIVNDLDRSTYAYRDNVNLK 594
            ...:..:||.....|.|.   ||              |..|.....:...|..:.|...:...|.
  Fly   500 VATLPPEIAVGAAAGGVA---GG--------------AGSRRGSSYVPEKLSFAAYEKFEGQMLI 547

  Fly   595 TALMSFVNAVLNYGPGQEN--------LEFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFF 651
            ..|:|.:.:......|..|        |:|..:|:|    :|:      |:...||.||.....:
  Fly   548 KWLISTMQSNPKSSSGDANQELFNTLALQFCNNLKY----VGV------LKQISNEHLDCGFSPY 602

  Fly   652 EMVR---------------AEDEKEFARRFKE--------EHVDTKS------AGSMFELLRRKL 687
            ||.:               .:.:|..|..|..        |.....|      |||:..:.....
  Fly   603 EMYQWTHTEQPTTSLPLTPGKLDKVAAWPFSSTPSGIRALESASLASLGAGGVAGSLATIATAST 667

  Fly   688 SHSPAYPHMLSLLQHMLLLPYTGHCTEHWLLIDRVVQQIVLQVEQRPNSDLIVDPDDPEK----- 747
            :.|.....:..:|:..||     :||. ...:..||.:::..|::.|..        |.|
  Fly   668 ASSDNQKTLQQILKKRLL-----NCTT-LAEVHAVVNELLSSVDEPPRR--------PSKRCVNL 718

  Fly   748 -QLKLAAESPVHDPDVAPLQIDVAKLVRLLVKEEQLTQARKRADELERENFDVQSRLAKKEQELD 811
             :|..|:|:.|::.:                        :..|:...:...|.:::
  Fly   719 TELLNASEATVYEYN------------------------KTGAEGCVKSFTDAETQ--------- 750

  Fly   812 LRMQEKEDLETGLARMRERLEKESAQHSQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVTEG 876
               .|.||.| |..:        ..|.|..|...::|:
  Fly   751 ---TESEDCE-GTCK--------CGQSSTKVSDNESAK--------------------------- 776

  Fly   877 SIPDDQKVAGLTGCNGAVSPPPAPPMLKAI------------------------PPPPPPMAPSM 917
              .|.:|...:     |..|||.||.|.|.                        ||||||.....
  Fly   777 --EDGEKPHAV-----APPPPPPPPPLHAFVAPPPPPPPPPPPPPPLANYGAPPPPPPPPPGSGS 834

  Fly   918 MPPPPPPCP-----GAPPPPPSMA-----QTMAPAP----------PKVDLPKKNVPQPTNPLKS 962
            .||||||.|     |.|||||.|:     .|::|||          .:.:..:|:...|..|::.
  Fly   835 APPPPPPAPIEGGGGIPPPPPPMSASPSKTTISPAPLPDPAEGNWFHRTNTMRKSAVNPPKPMRP 899

  Fly   963 FNWSKL---------PDAKLQGT-------------------------------VWSELDESKLY 987
            ..|:::         |.:....|                               :|:|::|:.|.
  Fly   900 LYWTRIVTSAPPAPRPPSVANSTDSTENSGSSPDEPPAANGADAPPTAPPATKEIWTEIEETPLD 964

  Fly   988 NNMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSKLKMSDM 1052
            |   ::...:|||......||..    ::|:|  |.||.  :.|:|..|::|..|:...|.:...
  Fly   965 N---IDEFTELFSRQAIAPVSKP----KELKV--KRAKS--IKVLDPERSRNVGIIWRSLHVPSS 1018

  Fly  1053 EISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRFLYEISKIPHYEQR 1117
            ||..||..:|:: .:.|:.::.:.....:.:|...:.|.:.....|...::||.:||.|....:|
  Fly  1019 EIEHAIYHIDTS-VVSLEALQHMSNIQATEDELQRIKEAAGGDIPLDHPEQFLLDISLISMASER 1082

  Fly  1118 LKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRG--ARGNASGFR 1180
            :..:.::..|..::..|..::.:|.:.|:::..|..|:.:..::|.||||||.|  .||.|.||.
  Fly  1083 ISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQADGFN 1147

  Fly  1181 LASLNRLADTKSSAAKGTTLLHYLVQ--VIERKFKDLLKLEDDIP-----HVREASKVSLGEMDK 1238
            |..|.:|.|.||..:. |||||::|:  :.:|:.:.:..||..:|     .|..|:::...|:.:
  Fly  1148 LDILGKLKDVKSKESH-TTLLHFIVRTYIAQRRKEGVHPLEIRLPIPEPADVERAAQMDFEEVQQ 1211

  Fly  1239 DIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVR 1303
            .|..|........|......::...:..:.|...|.||...|....|:|.....:.:..|...:|
  Fly  1212 QIFDLNKKFLGCKRTTAKVLAASRPEIMEPFKSKMEEFVEGADKSMAKLHQSLDECRDLFLETMR 1276

  Fly  1304 L--FGEDGSVL-----QPDEFFGIFDSFLAAFAEA-RHDNESFRRRQEEEEKRAKQEA------- 1353
            .  |......|     .||:||..:.:|...|.:. :.:..|......::.|:|:.|:
  Fly  1277 FYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFKDIWKKEITSLLNELMKKSKQAQIESRRNVSTK 1341

  Fly  1354 -------ELKKRTIERKNK 1365
                   .||:|.:.|::|
  Fly  1342 VEKSGRISLKERMLMRRSK 1360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:461886	55/271 (20%)
		Drf_FH3	551..737	CDD:461885	41/222 (18%)
		Smc	<765..>875	CDD:440809	11/109 (10%)
		FH2	950..1328	CDD:396655	99/433 (23%)
capu	NP_001137784.1	FH2	888..1315	CDD:214697	100/439 (23%)