Protein Alignment DAAM and for3

DIOPT Version :10

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: NP_588046.1
• Gene: for3 / 2539487
• PomBaseID: SPCC895.05
• Length: 1461
• Species: Schizosaccharomyces pombe
• Alignment Length: 1418
• Identity: 282/1418 - (19%)
• Similarity: 517/1418 - (36%)
• Gaps: 399/1418 - (28%)

  Fly   270 NSNCNGSSNTNGLGLRKWLSGNTSSNETPLQKHYRHQQKKKMPGFRGRRVWCGCFKDD--EPPEI 332
            ||:.:.|||.. :|....:|.:.:|:.:.||.....:.::.:          ....||  :|..:
pombe    20 NSSYSTSSNER-IGTPSTISLSENSDLSKLQSTNDFESREDL----------SLTSDDNNDPEYV 73

  Fly   333 CVVEGAFTLQTLTPTQPMPSVDELDTKFAELVEELDLTAPNKEAMLSLPA---------QKKWQI 388
            ......:..:|           :::.|.....|:|....|.:..:...|.         .|::..
pombe    74 MCYNTVYHQKT-----------KINDKLLSETEQLRKIYPLESRVFPKPTIVKEITNERTKRYTF 127

  Fly   389 YCSRKLPLDAADGPDAAAVTQPPTAEH-------YIERLKELVVHISLSPEDSPSHELGNRLDGH 446
            |           ..||     |.|.:|       |...||.:...|....|..|::.
pombe   128 Y-----------DDDA-----PLTNQHTVLDEATYNRILKRIDFFIEKVVEVPPTYH-------- 168

  Fly   447 AAFVDALKTALRTSTHSFVLRFVELDGLPALLDLLLQL---DIRVANSPLHTSLIGCIKALMNNS 508
              |:..|...||.....::..|.|.:|:.:||..|..|   ..|.:.:||.:.:|..:...:|:.
pombe   169 --FLSLLNVQLRIQPIWWMDEFAERNGIESLLSALRNLGHYPERASKTPLESQIIQSLFHCLNSE 231

  Fly   509 MGRAHVLAHP-------TAIDTIARSLAADNIRTKIAALEILGAVCLVPG--GHRKVLQAMLHFQ 564
            ..|....:..       .|:.|||.::.:.::.:...|..:|..:|...|  ..:.|::|.....
pombe   232 NCRRRYQSSAKCSVPGFNALGTIAETVLSKSLNSARMATFLLKFLCNKKGLSYFKAVIRAFEWLV 296

  Fly   565 VFATERTRFQSIV---NDL--------DRSTYA--YRDNVNLKTALMSFVNAVL----NYGPGQE 612
            .....:|||.:.:   ||:        |.|..|  :.|.......|:.::.|.|    :......
pombe   297 EQKLSKTRFSAWMHSFNDVITGVRVCADSSPQAIVHMDEFEDTDCLIDYLVATLALIRDLCAAPP 361

  Fly   613 NLEFRLHLRYEFLMLGIQPVIDKLRTHENETLDRHL-DFFEMVRAEDEKEFARRFKE----EHVD 672
            :|:.|..||:|.|..|:|..||.|....|    ||: |..:::..|...: ||||:.    .:||
pombe   362 DLQLRCALRHELLSAGLQKAIDSLLKWRN----RHVRDALQLLIKEHNAD-ARRFRSGSDVNNVD 421

  Fly   673 TKSAGSMFELLRRKLSHSP-----------------------------------------AYPHM 696
            .|....  ::..|:.||:|                                         :....
pombe   422 RKCVKK--QMNYREESHTPHGNTTRKTSTPVSNNRPTTPEQQAVWDVFQRIYTRFTGSEGSKESF 484

  Fly   697 LSLLQH-------------MLLLPYTGHCTEHW------------LLIDRVVQQI-----VLQVE 731
            :.||::             |.||.:|....|.:            :|..|::.::     :.:.:
pombe   485 IKLLEYFVTEPDNGKIQKSMQLLTHTLEALEGFKTAKADTNVGLTILSQRLLDKLGTAEEIAEYK 549

  Fly   732 QRPNSDLIVDPDDPEKQLKLAAESPVHDPDVAPLQIDVAKLVRLLVKEEQLTQARKRADELEREN 796
            .:.|..::     ..|.||...||.:...:|.|              .:.:...:|:.|||:.|.
pombe   550 TKYNGAML-----ENKHLKEQVESMLSQLNVGP--------------RDPMQFLKKQLDELKAEL 595

  Fly   797 FDVQSRLAKKEQELDLRMQEKEDLETGLARMRERLEKESAQHSQAVQRAQTAEMRAEDLQHRLIS 861
            ....:.||..::|.:.|.:.:......|....|.::..:.||.|.....:.:: ..:.:..|.:|
pombe   596 NLRDNLLASMQREFETRYRAQIQAYNKLQSQMEHVQNSNEQHLQPGLLNKVSK-SFDSVHRRNLS 659

  Fly   862 EQQERARLERL-------VTEGS-IP----DDQKVAGL----TGCNGAVSPPPAPP--------- 901
            :....|..|:.       :..|| ||    ...|...|    :|...:.||.|..|
pombe   660 QDSLDAMTEQFSYHVEPNILSGSGIPVRVHTPSKTEDLDESFSGSEISSSPSPLLPDVSDTVEEQ 724

  Fly   902 ---MLKAIPPPP---------------PPMAPSM-MPPPPPPCPGA--------PPPPPSM---- 935
               :||:.||||               ||.||.| .||||||.||.        |||||::
pombe   725 QKLLLKSPPPPPPAVIVPTPAPAPIPVPPPAPIMGGPPPPPPPPGVAGAGPPPPPPPPPAVSAGG 789

  Fly   936 AQTMAPAP-----PKVD-----------------------------------LPK-KNVPQPTNP 959
            ::..||||     ||:|                                   :|. :::.:||.|
pombe   790 SRYYAPAPQAEPEPKIDETSLTEEQKIQLEEARKQRKAADDAARAAIEKYTSIPSLRDLHKPTRP 854

  Fly   960 LKSFNWSKL-----PDAKLQGTVWSELDESKLYNNMELESIDKLFSAYQKNGVSATDGSYEDLRV 1019
            ||..:|.::     |:...:..:..::......:|..|:.:|:.|....:....|.:.|  |.|
pombe   855 LKRVHWQRVDPLPGPNVFTKFCLNFDITAKVFIDNGLLDFLDEKFDNTPREDFVAVEIS--DQR- 916

  Fly  1020 TGKAAKQKVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLL---KFTPS 1081
                     .|::.....||..|:|.  .:|:|.:.              |:|::.|   .|.|:
pombe   917 ---------SSLLPDTVEQNMAIILR--SVSNMPVE--------------DLVQKFLVEPDFLPA 956

  Fly  1082 ----------AEERALLD---------------EHSEDIESLARADRF--LYEISKIPHYEQRLK 1119
                      |...|..|               |.:.|:.||:..::|  |:.::...::::|:|
pombe   957 SILYFDRASLASTNAYTDPFIPYSTDYTKKNPKEPTADVNSLSYFEKFFVLFVVNLRHYFQERMK 1021

  Fly  1120 SLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGARGNASGFRLASL 1184
            :|.::......:..|..|:..|::.|..:...:...:..:::|.:|||.|. ....||.|.|..:
pombe  1022 ALKFRSTLFGDLEILEVRMKEVIDTSDSIMEDKNFAEFFQVLLIIGNYFNE-PYDRASAFSLYMI 1085

  Fly  1185 NRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLAD 1249
            .|| :|...::...||:||..::|..:|.:||:.|.....::..|..::..|...:.    |..|
pombe  1086 YRL-ETLRDSSSALTLMHYFDEIIRTRFPELLQAESTFKKIQSVSGYNIDAMVAGVD----GAYD 1145

  Fly  1250 VAREIEFHRSSGPAQQGDRFLP------VMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGED 1308
            ...:.:.....|...:.|:..|      ::.|:..:|..|...::....||.|:.:..|:...|.
pombe  1146 EFCDFQTSLKDGALSKCDQHHPDDKAYDILSEWLPEAKERIRNIKKLKTDMLTKLENTVKYLCEY 1210

  Fly  1309 GSVLQ-PDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQEAELKKRTIERKNKTGLMTSV 1372
            .|:.: .:.||...:||...::.|:.:||   .|.|:|::|...|.  :.:.|..:.||.::...
pombe  1211 DSIDKVRNSFFKNLNSFYEMYSIAKAENE---ERFEKEKRRIMSED--RDKLIRGRQKTSIVAKY 1270

  Fly  1373 ARNLGL------KSGSSNGDPDS----------------PAKGGDNKGEFDDL 1403
            .....|      |..:::.|.:|                .||.||: .|.:||
pombe  1271 RNKRELPEDSDDKQDTASKDKNSLETIDEKMEDASKIEGDAKTGDD-NEMEDL 1322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:461886	41/224 (18%)
		Drf_FH3	551..737	CDD:461885	52/280 (19%)
		Smc	<765..>875	CDD:440809	18/116 (16%)
		FH2	950..1328	CDD:396655	84/420 (20%)
for3	NP_588046.1	Drf_FH3	307..511	CDD:461885	41/210 (20%)
		FH2	846..1295	CDD:214697	99/487 (20%)