Protein Alignment DAAM and Fhdc1

DIOPT Version :9

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: NP_001028473.2
• Gene: Fhdc1 / 229474
• MGIID: 2684972
• Length: 1149
• Species: Mus musculus
• Alignment Length: 553
• Identity: 161/553 - (29%)
• Similarity: 267/553 - (48%)
• Gaps: 83/553 - (15%)

  Fly   885 AGLTG-CNGAVSPPPAPPMLKAIPPPPPP-------MAPSMMPPPPPPCPGAPPPPPSMAQTMAP 941
            |.:|| .:.:.||||.||     ||||||       .:||..||.|||.||.||.||       |
Mouse    23 AFMTGQTSPSASPPPPPP-----PPPPPPCPHSGEGFSPSPPPPLPPPLPGGPPIPP-------P 75

  Fly   942 APPKV----------DLPKKNVPQPTNPLKSFNWSKLPDAKLQG--TVWSELDESKLYNNMELES 994
            .||.:          .|.||      ..::||.|..:|:.:::|  .:|:...:.:....::.::
Mouse    76 PPPGLPSVSYLNGYSSLGKK------KRMRSFFWKTIPEEQVRGKTNIWTLAAKQQHQYQIDKKT 134

  Fly   995 IDKLF--------SAYQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSKLKMSD 1051
            |::||        ::..|.| .|.:.|:.|.|        :.::|:|.:|:.|..|.|.:.|.|.
Mouse   135 IEELFGQQEDTSKASLPKRG-GALNSSFRDAR--------EEVTVLDAKRSMNIGIFLKQFKKSP 190

  Fly  1052 MEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRFLYEISKIPHYEQ 1116
            ..|.:.|. ...:|....:.:.::||..|.:||...|...:.|:..|:.||.||:.:.::|:|..
Mouse   191 QSIVEDIY-QGKSEHYGSETLREILKLLPESEEVKKLKAFNGDVSKLSLADSFLHCLIQVPNYSL 254

  Fly  1117 RLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGA-RGNASGFR 1180
            |::::..||.|:.:.:.|...|.::..|::|:.....|..:|.|||..||.||.|. .|||.||:
Mouse   255 RIEAMVLKKEFLPSCSSLFKDIRTLRAATKELMLCEELHSILHLVLQAGNIMNAGGYAGNAVGFK 319

  Fly  1181 LASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRT 1245
            |:||.:|||||:: ..|..|||::.|..:::...||...:.:.||:|.|::||...:.::..|..
Mouse   320 LSSLLKLADTKAN-KPGMNLLHFVAQEAQKQDAILLNFSEKLQHVQETSRLSLDITEAELHSLFV 383

  Fly  1246 GLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGS 1310
            ....:...|:..:..  .||       |.:|...|..:.||||...::::......:..|.||..
Mouse   384 RTKSLQENIQLDQEL--CQQ-------MEDFLQFAVEKLAELELWKRELQGEAHTLIDFFCEDKE 439

  Fly  1311 VLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQEAELKKRTIERKNKTGLMTSVARN 1375
            .::.||.|.||..|...|.:|..||..   |:|:|.|:.:::.|::::....  .||.:.|..|:
Mouse   440 TMKLDECFQIFRDFCTRFNKAVKDNHD---REEQERKQLQRQKEMEQKRYSW--STGELGSFGRS 499

  Fly  1376 LGLKSGSSNGDPDSPAKGGDNKGEFDDLISALR 1408
                  ||..|....||.|.     :||.|.|:
Mouse   500 ------SSENDVQMLAKTGT-----EDLPSFLK 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920
		Drf_FH3	551..737	CDD:283917
		FliJ	779..>875	CDD:280262
		FH2	950..1328	CDD:280362	106/388 (27%)
Fhdc1	NP_001028473.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..79		30/67 (45%)
		FH2	94..458	CDD:366959	106/389 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	464..540		20/74 (27%)
		PHA03307	524..>981	CDD:223039
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	554..660
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	681..1149
		PHA03247	<823..1064	CDD:223021
		MTBD, microtubule-binding domain. /evidence=ECO:0000250|UniProtKB:Q9C0D6	960..1086

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810