DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DAAM and fozi-1

DIOPT Version :9

Sequence 1:	NP_001188522.1	Gene:	DAAM / 31075	FlyBaseID:	FBgn0025641	Length:	1463	Species:	Drosophila melanogaster
Sequence 2:	NP_001379050.1	Gene:	fozi-1 / 176308	WormBaseID:	WBGene00010453	Length:	732	Species:	Caenorhabditis elegans

Alignment Length:	417	Identity:	98/417 - (23%)
Similarity:	186/417 - (44%)	Gaps:	78/417 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   906 IPPPPPPM--APSMMPPPPPPCPGAPPPPPSMAQTMAPAPPKVDLPKKNVPQPTNPLKSFNWSKL 968
            :||...||  ..:|:.      ..:.|.|.|::.::.|..|  ..|.:|. || ..:||.:|:.|
Worm   333 VPPITMPMQDLKTMLD------ANSSPSPISLSSSIIPIQP--IKPGENA-QP-KYMKSLDWTIL 387

  Fly   969 PDAKLQGTVWSELDESKLYNNMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQKVLS--- 1030
            .|.:::|||:::     ..:||||         |.:|.....:.:        ||.:..|||
Worm   388 NDLQMKGTVFAD-----CRSNMEL---------YAENIARKIENT--------KAFQSFVLSDDM 430

  Fly  1031 --VIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSE 1093
              |::..|        |::.:...|:..||..||. :.|..::|:.||:..|:..:..||    .
Worm   431 RTVVEEVR--------SRVSIQLFEVMFAIHRMDI-KVLNQNLVDSLLQIAPTNSDAQLL----R 482

  Fly  1094 DIESLARA-DRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKL 1157
            .:|:|:.. :.||..::||.|.|::|:::.:..||...:..|...|.....|.:.::.||.||.:
Worm   483 KMENLSDPNEEFLLGLTKIDHIEEKLETMKHMYRFPEQVELLKENIIKYEIAVKVLSESRALRNV 547

  Fly  1158 LELVLA---LGNYMNRGARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLE 1219
            ::||||   :|.:.:|... :.:||.::.::.:..|.:.:  |.::...||.::    ||.:.|:
Worm   548 MQLVLAILNIGFFDDRQCL-SINGFSVSDISSILSTNTPS--GQSVQSILVTIL----KDEINLD 605

  Fly  1220 DD-----IPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQ 1279
            .|     |..:.:.....:..:.:|:.:|........:|:|...|:.|          :.||...
Worm   606 LDELFGLIDVLEKIENDDVNSVAQDLMVLDDKTVRAEKEMEHSGSNIP----------LSEFVEN 660

  Fly  1280 ASVRFAELEDKFQDMKTRFDRAVRLFG 1306
            |.....|..:.|:.:||..:|.....|
Worm   661 AKTISKERWEHFKSLKTSIERLTIYLG 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920
		Drf_FH3	551..737	CDD:283917
		FliJ	779..>875	CDD:280262
		FH2	950..1328	CDD:280362	87/371 (23%)
fozi-1	NP_001379050.1	FH2	370..726	CDD:214697	88/372 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910