DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DAAM and LOC101883438

DIOPT Version :9

Sequence 1:	NP_001188522.1	Gene:	DAAM / 31075	FlyBaseID:	FBgn0025641	Length:	1463	Species:	Drosophila melanogaster
Sequence 2:	XP_005162511.2	Gene:	LOC101883438 / 101883438	-ID:	-	Length:	823	Species:	Danio rerio

Alignment Length:	580	Identity:	129/580 - (22%)
Similarity:	236/580 - (40%)	Gaps:	74/580 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   803 LAKKEQELDLRMQEKEDLETGLARMRERLEKESAQHSQAVQRAQTAEM----RAEDLQHRLISEQ 863
            |...:.:...|:.:.|.:.|..|.|.||.....|.....|...:.::.    .|.|.....::|.
Zfish   267 LRNDKNDFLFRIPKSEHMTTPEALMNERDSWMKAIRELCVDWKRKSQFEDFYEAPDSDFINVTEP 331

  Fly   864 Q---------------ERARLERLVT--EGSIP-------------DDQKVAGLTGCNGAVSP-- 896
            :               :|.||.|..|  ..::|             ..:|....|.|.....|
Zfish   332 ESKTQNNHEPPPVPPSQRPRLPRTPTAVHPALPTTPEPLEPLEAPKPPRKPNRSTFCRSVALPLT 396

  Fly   897 PPA------PPMLKAIPPPPPPMAPSMMPPPPPPCPGAPPPPPSMAQTMAPAPPKVDLPKKNVPQ 955
            |||      ||.|..:.||..|:|...:..|..|.|.|||.||:   ..||.||.:.:....:.:
Zfish   397 PPAAACSTSPPTLPILLPPASPVASGAVLGPASPVPSAPPAPPA---PPAPLPPPLPIKSNQLSE 458

  Fly   956 PTNPLKSFNWSKLPDAKLQGTVWSELDESKLYNNMELESIDKLFSAYQKNGVSAT--DGSYEDLR 1018
            .|   |:|:|..:...|::.::||.....|:    |:::: :||..:   ||..|  .||.|
Zfish   459 RT---KAFHWDLVAQDKIEKSMWSRRSLRKI----EIDTL-RLFELF---GVKETVNSGSLE--- 509

  Fly  1019 VTGKAAKQKVLSVIDGRRAQNCTILLSKLKMSDMEISKAILSMDSNE-QLQLDMVEQLLKFTPSA 1082
                 :...:..:::.:.|.|..|.|....:...|:...:|.::..| .|..:.:..|.::.|:.
Zfish   510 -----SNSTIEIMLNSKIAHNFNIFLKSFPVQPKELKDKLLIINEEEGGLSDEHITSLRRYVPTP 569

  Fly  1083 EERALLDEHSEDIESLARADRFLYEISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASRE 1147
            ::..:...|..|...|...|:::.|:..||:....|..|...:...:::.||.|.|...:...::
Zfish   570 DDVEMYKSHKGDSAELHVVDQYMMEMCNIPNLSAHLDLLLTMRELPISMEDLAPLIIQKIHMCQQ 634

  Fly  1148 VARSRRLRKLLELVLALGNYMNRGA-RGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERK 1211
            :........:||.:||:|||:|:.| :..|.||||:||.:::..:.:..| .||||.||:.|..:
Zfish   635 LWACESFVSVLEYLLAVGNYLNQNAGKDRAKGFRLSSLTKISQLRGNNRK-FTLLHALVEQIMLR 698

  Fly  1212 FKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREF 1276
            ...|.....::.........|:..:..::.::|.....|.:..:.|:......|..:|...|:..
Zfish   699 DPRLATFFLELAEFETVPGASVKGLTAEVDVVRNEFQKVIQYRKAHKRKNMGNQQIKFFQDMKTA 763

  Fly  1277 HAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGSVLQPD--EFFGIFDSFLAAFAEARHD 1334
            ..:......:|..:.::|:..:...:..|||.   |..|  |.||....|:..|.:...:
Zfish   764 IQKHEADLRQLMKRCEEMRKLYTDILVKFGEP---LDQDSQELFGWICQFINDFKKVHSE 820

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920
		Drf_FH3	551..737	CDD:283917
		FliJ	779..>875	CDD:280262	18/92 (20%)
		FH2	950..1328	CDD:280362	83/383 (22%)
LOC101883438	XP_005162511.2	FH2	459..815	CDD:302999	83/378 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010