DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DAAM and LOC101882071

DIOPT Version :9

Sequence 1:	NP_001188522.1	Gene:	DAAM / 31075	FlyBaseID:	FBgn0025641	Length:	1463	Species:	Drosophila melanogaster
Sequence 2:	XP_005170655.1	Gene:	LOC101882071 / 101882071	-ID:	-	Length:	1009	Species:	Danio rerio

Alignment Length:	570	Identity:	146/570 - (25%)
Similarity:	249/570 - (43%)	Gaps:	100/570 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   922 PPPCPGAPPPPPSMAQTMAPAPPKVDLPKKNVPQPTNPLKSFNWSKLPDAKL----QGTVWSELD 982
            |||.|  |||||              ||..:..:....:|||.|..:|:.::    :..:||...
Zfish    25 PPPAP--PPPPP--------------LPAVHSAERKRRVKSFFWKPIPEDRVRQQDRTNLWSLRQ 73

  Fly   983 ESKLYN-NMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSK 1046
            :|:... ::::.:|.:||...|:.         ..||......:::.:|::|.:|:.|.:|.|..
Zfish    74 DSREQTLHIDITAIQELFGHPQET---------PTLRPAPVRDRRQQVSLLDSKRSLNISIFLKH 129

  Fly  1047 LKMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRFLYEISKI 1111
            .|.|...:..|:|..::. ....:.:::|||..|..:|...|...|.|::.||..|.|::::..:
Zfish   130 FKKSPECLLDAVLQGNTG-VFTAESLKELLKLLPEEDEVKNLQMFSGDLKDLAPPDAFIHQLINL 193

  Fly  1112 PHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNR-GARGN 1175
            |.||..|::|..|:.|..:|..:...::.::.|..|:.....|..:|.|||..||.||. |:.||
Zfish   194 PRYEDLLQALLLKEEFFPSITVMKDELSVILSAINELLNCEELHTVLHLVLQAGNVMNAGGSAGN 258

  Fly  1176 ASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDI 1240
            |.||||:||..|||||:: ..|..|||::  .:|.:.||||...|.:.||:.|::|.:..:..|.
Zfish   259 AVGFRLSSLLSLADTKAN-KPGMNLLHFV--ALEAEKKDLLLFPDKLLHVQRAARVCVDSIHTDF 320

  Fly  1241 QMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLF 1305
            ..|...:..:.:.:.....             ::.|...|:....:|.....:::...|..:..|
Zfish   321 NSLSRRVLQLQQILHTDEE-------------LQSFLKSAAEALQDLSVSIDELQRESDALLDFF 372

  Fly  1306 GEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQEAELKKRTIERKNKTGLMT 1370
            .||....:.||...||.:|.:.|.:|..:|.. |...||..:|..:|:|.|:.:.......|
Zfish   373 CEDKDSFKLDECLRIFQNFCSKFRKAVQENVE-RGMWEESRRRRLRESEDKRHSWAGHEGAG--- 433

  Fly  1371 SVARNLG---LKSGSSNGDPDSPAKGGDNKGEFDDLISAL---RTGDVFGEDMAKFKRSRKARVL 1429
                  |   |:| ||..|.::..|   .:|..:.|.|.|   |..          :||::.:::
Zfish   434 ------GAYELRS-SSEADVEAALK---REGLLELLHSPLLRPRNN----------QRSKQQKIV 478

  Fly  1430 NGGGSSTGHTSPPRHG------SLQRE----------ESGRERERTVRRQ 1463
            |      .|..||.|.      .:|.|          ||..:.|..|..|
Zfish   479 N------THELPPIHALSITDTQVQNETNAQTQASECESSTKTEEVVDHQ 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920
		Drf_FH3	551..737	CDD:283917
		FliJ	779..>875	CDD:280262
		FH2	950..1328	CDD:280362	98/383 (26%)
LOC101882071	XP_005170655.1	FH2	44..396	CDD:302999	98/377 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010