Protein Alignment DAAM and daam2

DIOPT Version :9

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: XP_031757864.1
• Gene: daam2 / 101731433
• XenbaseID: XB-GENE-6049503
• Length: 1082
• Species: Xenopus tropicalis
• Alignment Length: 1190
• Identity: 542/1190 - (45%)
• Similarity: 761/1190 - (63%)
• Gaps: 158/1190 - (13%)

  Fly   312 PGFRGRRVW---CGCFKDDEPPEICVVEGAFTLQTLTPTQPMPSVDELDTKFAELVEELDLTAPN 373
            |..|.|..:   | ||...|.|||.:.:.. .|..:....|:||.:||:.:|:|||:|||||..|
 Frog     5 PRKRSRHAFGFLC-CFGSSEHPEINLKDNN-PLHFMEFAGPIPSAEELNARFSELVDELDLTDKN 67

  Fly   374 KEAMLSLPAQKKWQIYCSRKLPLDAADGPDAAAVTQPPTAEHYIERLKELVVHISLSPEDSPSHE 438
            :|||.:||.:||||||||:|   ...:.|:..|.:.|   ::||:|:..:....:|...|....|
 Frog    68 REAMFALPPEKKWQIYCSKK---KEQEDPNKLATSWP---DYYIDRINSMAAMQTLYAFDEEDTE 126

  Fly   439 LGNRLDGHAAFVDALKTALRTSTHSFVLRFVELDGLPALLDLLLQLDIRVANSPLHTSLIGCIKA 503
            :.|::      |:.|||||||....||.||:|||||..||:.|..:|...:.|.:|||:||||||
 Frog   127 MRNKI------VEDLKTALRTQPMRFVTRFIELDGLTCLLNFLKSMDYETSESRIHTSVIGCIKA 185

  Fly   504 LMNNSMGRAHVLAHPTAIDTIARSLAADNIRTKIAALEILGAVCLVPGGHRKVLQAMLHFQVFAT 568
            |||||.|||||||||.:|:.|::||..:||:||||.|||||||||||.||:||||||||:||:|.
 Frog   186 LMNNSQGRAHVLAHPESINIISQSLRTENIKTKIAVLEILGAVCLVPDGHKKVLQAMLHYQVYAA 250

  Fly   569 ERTRFQSIVNDLDRSTYAYRDNVNLKTALMSFVNAVLNYGPGQENLEFRLHLRYEFLMLGIQPVI 633
            ||||||:::|:||||...|||.||||||:|||:|||||.|.|::|||||||||:|||||||||||
 Frog   251 ERTRFQTLLNELDRSMGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHLRFEFLMLGIQPVI 315

  Fly   634 DKLRTHENETLDRHLDFFEMVRAEDEKEFARRFKEEHVDTKSAGSMFELLRRKLSHSPAYPHMLS 698
            ||||.|||.|||||||||||||.|||.|.|:||...|:|||||..||:|:::||.|:.:||::||
 Frog   316 DKLRRHENATLDRHLDFFEMVRNEDEIELAKRFDMSHIDTKSATQMFDLIKKKLKHTDSYPYLLS 380

  Fly   699 LLQHMLLLPY--TGHCTEHWLLIDRVVQQIVLQVEQRPNSDLIVDPDDPEKQLKLAAESPVHDPD 761
            :|||.|.:||  .|...:||.|:||::||||||.|:.                        .|||
 Frog   381 ILQHCLEMPYKWNGSTIQHWQLLDRILQQIVLQDEKG------------------------EDPD 421

  Fly   762 VAPLQ-IDVAKLVRLLVKEEQLTQARKRADELERENFDVQSRLAKKEQELDLRMQEKEDLETGLA 825
            ||||: .:|..::::||.|.::.|.|::|::..:::.::.|||.|||:|.:::.||||::...|.
 Frog   422 VAPLENFNVKNIIKMLVNENEVKQWREQAEKFRKDHTELSSRLEKKERECEIKTQEKEEMMKTLN 486

  Fly   826 RMRERLEKESAQHSQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVTEGSIPDDQKVAGLTGC 890
            :|:::|:|||::..|           |.|....|:|:      |..|...|::
 Frog   487 KMKDKLQKESSELRQ-----------ARDHMTDLMSQ------LNELSNGGTL------------ 522

  Fly   891 NGAVSPPP----------APPMLKAIPPPPPPMA-PSM--MPPPPPPCPGAPPPPPSMAQTMAP- 941
              :..|||          .||:.:.:||||||:. |..  .||||||.||||||||.     ||
 Frog   523 --SFPPPPPPPPGGPFVLPPPLPENLPPPPPPLQFPCFPPPPPPPPPPPGAPPPPPG-----APP 580

  Fly   942 -------APP------KVDLPKKNVPQPTNPLKSFNWSKLPDAKLQGTVWSELDESKLYNNMELE 993
                   |||      ...|.||::|||::.|||||||||.:.|:.||:|:|:|:...:..::|:
 Frog   581 FFSMGMQAPPLTTFNYGTSLRKKSIPQPSHALKSFNWSKLNEDKINGTIWNEIDDIHAFKMLDLD 645

  Fly   994 SIDKLFSAYQKNG--VSATD------GSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSKLKMS 1050
            ..:::|||||::.  :|.|.      .|.|||.::.:  |.|.||||||||||||.|||||||:|
 Frog   646 EFERMFSAYQRHQDLLSNTSLKQKDMDSMEDLYLSTR--KVKELSVIDGRRAQNCVILLSKLKLS 708

  Fly  1051 DMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSEDIESLARADRFLYEISKIPHYE 1115
            :.||.:||:.||..|.|..||:||||||.|...:..||:||..:||.:|||||||||:|:|.||:
 Frog   709 NEEIRRAIMEMDEQEDLPKDMLEQLLKFVPEKSDVDLLEEHKHEIERMARADRFLYEMSRIDHYQ 773

  Fly  1116 QRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGARGNASGFR 1180
            |||::|.:||:......:..|::.:::.|.:|:.||:||::|.|:|||.|||||:|.||||.|||
 Frog   774 QRLQALFFKKKLPERFAETKPKVEALLLACKELMRSKRLKQLFEVVLAFGNYMNKGQRGNAFGFR 838

  Fly  1181 LASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQMLRT 1245
            :||||::.|||||..:..||||||:.:.||.:.|:|.::.::.|:.:|:||:|.|::|::..::.
 Frog   839 VASLNKIIDTKSSIDRNITLLHYLIMIFERTYPDILNIQTELQHLTDAAKVNLVELEKEVGNIKN 903

  Fly  1246 GLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKTRFDRAVRLFGEDGS 1310
            ||..|..|:|:.|.. ..:.||||:|||.:|...|....:||||...:.:.::::|::.|||...
 Frog   904 GLRAVESELEYQRRQ-YREAGDRFVPVMSDFITVAGFSVSELEDLLSEARDKYNKAMKHFGEVEG 967

  Fly  1311 VLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAKQEAELK-KRTIERKNKTGLMTSVAR 1374
            .:||||||||||:||.:||||:.|.|:.|:::||||:||:.||.|| :|..||:.|.....|.:.
 Frog   968 KMQPDEFFGIFDTFLQSFAEAKQDLENMRKKKEEEERRARMEAMLKEQRDKERRLKKAKADSTSE 1032

  Fly  1375 NLGLKSGSSNGDPDSPAKGGDNKGEFDDLISALRTGDVFGEDMAKFKRSRKARVLNGGGSSTGHT 1439
            .:                     ||||||:||||:|:||.:|::|.||:||
 Frog  1033 EV---------------------GEFDDLVSALRSGEVFDKDLSKLKRNRK-------------- 1062

  Fly  1440 SPPRHGSLQREESGRERERT 1459
               |.|: |..::.|||..|
 Frog  1063 ---RSGN-QILDTSRERAVT 1078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:283920	101/198 (51%)
		Drf_FH3	551..737	CDD:283917	125/187 (67%)
		FliJ	779..>875	CDD:280262	28/95 (29%)
		FH2	950..1328	CDD:280362	182/385 (47%)
daam2	XP_031757864.1	Drf_GBD	45..230	CDD:399398	100/196 (51%)
		Drf_FH3	233..437	CDD:368862	133/227 (59%)
		FH2	602..985	CDD:396655	182/385 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	369	1.000	Domainoid score	I903
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	989	1.000	Inparanoid score	I308
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1204639at2759
OrthoFinder	1	1.000	-	-		FOG0000085
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1795
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060