Protein Alignment DAAM and fmnl1b

DIOPT Version :10

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: NP_001429487.1
• Gene: fmnl1b / 100536330
• ZFINID: ZDB-GENE-130306-1
• Length: 1027
• Species: Danio rerio
• Alignment Length: 1170
• Identity: 299/1170 - (25%)
• Similarity: 502/1170 - (42%)
• Gaps: 266/1170 - (22%)

  Fly   346 PTQPMPSVDELDTKFAELVEELDLTAPNKEAMLS-LPAQKKWQIYCSRKLPLDAADGPDAAAVTQ 409
            |..|.||.:||:.:|:.::..::| .|:|..:|| ..::|||::.|.:          :...|..
Zfish    31 PKLPQPSEEELEERFSIVLNSMNL-PPDKVMLLSQYDSEKKWELVCDQ----------ERFQVKN 84

  Fly   410 PPTAEHYIERLKELVVHISLSPEDSPSHELGNRLDGHAAFVDALKTALRTSTHSFVLRFV--ELD 472
            ||:|  ||::||.::       |.....:...|:......:..|:.:|||:...:...|:  |.:
Zfish    85 PPSA--YIQKLKSVL-------EQGGGRKFKRRVQESTQVLRELEISLRTNHIGWAEEFLNEENN 140

  Fly   473 GLPALLDLLL-------------------------QLDIRVANSPLHTS---------------- 496
            ||..|:|.|.                         .|.....|||.|.|
Zfish   141 GLDVLVDYLSFAQRAVIYDMDSSSENGSFEEKSVEDLTTSATNSPTHNSPRSARPFTTRKALRYS 205

  Fly   497 -----------LIGCIKALMNNSMGRAHVLAHPTAIDTIARSLAADNIRTKIAALEILGAVCLVP 550
                       .|.|::|:||..:|...|.|||:.::.|..||...:.|||...||:|.|||||.
Zfish   206 RMLSQNNHLHLCIMCLRAIMNYQLGFNQVTAHPSCVNEITLSLNNRSARTKALVLELLAAVCLVR 270

  Fly   551 GGHRKVLQAMLHFQVFATERTRFQSIVNDLDRSTYAYRDNVNLKTALMSFVNAVLNYGPGQENLE 615
            |||..:|.|..:|:....|:.||:.::......    ..|::...|.|.|:|.|::   ..|::.
Zfish   271 GGHEMILAAFNNFREVCGEKNRFEKLMEYFRNE----ESNIDFMVACMQFINIVVH---SVEDMN 328

  Fly   616 FRLHLRYEFLMLGIQPVIDKLRTHENETLDRHLDFFEMVRAEDEKEFARRFKEEHVDTK-SAGSM 679
            ||:.|:|||..||:...::||...|:|.|...:                   :.::|.. ..|:|
Zfish   329 FRVFLQYEFTQLGLDSYLEKLNMTESERLQIQI-------------------QAYLDNVFDVGAM 374

  Fly   680 FELLRRKLSHSPAYPHMLSLLQHMLLLPYTGHCTEHWLLIDRVVQQIVLQVEQRPNSDLIVDPDD 744
            .|....|          .:|::|                         |:..|..|:.|
Zfish   375 LEDAEAK----------NTLMEH-------------------------LEELQEQNTQL------ 398

  Fly   745 PEKQLKLAAESPVHDPDVAPLQIDVAKLVRLLVKEEQLTQARKRADELERENFDVQSRLAKKEQE 809
                     .:.:|       |.::..|.:....|:||.|:.|:.:.|:....:.|::|.:
Zfish   399 ---------NTRLH-------QCEIEALEKTTDLEQQLIQSSKQVELLKESVKEAQTQLQQ---- 443

  Fly   810 LDLRMQEKEDLETGLARMRERLEKESAQHSQAVQRAQTAEMRAEDLQHRLISEQQERARLERLVT 874
              |::|:::|.:|         ..|:.||:. ..|.|| :|:.|.:             |:.||.
Zfish   444 --LQLQQQKDRQT---------RSETQQHTH-TDRQQT-QMQMEKM-------------LQLLVE 482

  Fly   875 EGSIPDDQKVAGLTG------------CNGAVSPPPAPPMLKAIPPPPPPMAPSMMPPPPPPCPG 927
            .|.|..::..:|...            |:...||.|..|     ||||.|..|.  ||||||...
Zfish   483 RGLIRMERSASGALDLHIIAAANTTDKCSKETSPVPQSP-----PPPPVPAPPP--PPPPPPLAL 540

  Fly   928 APPPPPSMAQTMAPAPPKVDLPKKNVPQPTNPLKS------FNWSKLPDAKLQGTVWSELDESKL 986
            |||..|.:.:|   ...|..:..|      .|:|:      .||..|.:.::.|||::|||:..:
Zfish   541 APPTSPFIGRT---GTIKTGVKGK------QPIKTKYRMPLLNWQALMEEQVAGTVFTELDDQTV 596

  Fly   987 YNNMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQKVLSVIDGRRAQNCTILLSKLKMSD 1051
            ...:.::..::||..  |...:..|.....::|..||:.:  :|:::..||:|..|.|.|..||.
Zfish   597 LQELNMDVFEELFKT--KAQSAPVDVGTLKVKVAQKASSK--ISLLEPNRAKNLAITLRKAGMST 657

  Fly  1052 MEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEHSED---IESLARADRFLYEISKIPH 1113
            .:|..||.:.:. |.|:.|.:|.|.:|.||..|..|:..:...   :..|:..|||:...||||.
Zfish   658 AQICTAIQTYNL-ELLKSDFLELLERFVPSDYELKLIQNYERSGRPLVELSEEDRFMMAFSKIPR 721

  Fly  1114 YEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRGARGNASG 1178
            ..||:.:|.:...|..::..|.|::.:|:.||:.:..|.:|:|:||::||.|||||.|.||:|.|
Zfish   722 LTQRISTLTFMGSFSESVLILKPQLNAVISASKSIRSSSKLKKILEIILAFGNYMNSGKRGSAYG 786

  Fly  1179 FRLASLNRLADTKSSAAKGTTLLHYLVQVIERKFKDLLKLEDDIPHVREASKVSLGEMDKDIQML 1243
            |||.||:.|.|.||:..| .||||::|.:|:.|:..|.....::..:.:|:.|||..:..|:..|
Zfish   787 FRLQSLDLLLDMKSTDRK-QTLLHFIVSIIQDKYPQLSNFHTELHFLDKAALVSLDSVLSDVCSL 850

  Fly  1244 RTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDKFQDMKT---RFDRAVRLF 1305
            :.|:..|.:|:|..::|....|   |:...|..          |:...:|..|   .:...|..|
Zfish   851 QKGMDVVCKELEQQQNSSVLTQ---FICTNRGL----------LDTLIKDSTTAQEAYQSVVEYF 902

  Fly  1306 GEDGSVLQPDEFFGIFDSFLAAFAEARHDNESFRRRQEEEEKRAK---QEAELKKRTIERKNKTG 1367
            ||:.....|..||.:|..|:.|:.....:.:..|:|..:.|:.|.   .:|.:.::...|..:..
Zfish   903 GENPKSTPPSAFFPVFTRFIKAYKLCEQEIDQRRKRLSDSEETADLKFSDAPVHRQKPLRLPQLD 967

  Fly  1368 LMTSVARNLGLKSGSSNGDPDSPAKGGDNKGEFDDLISALRTGDVF----GEDMAKFKRSRKARV 1428
            |::.:.|.           ..||.......|..:|:|:.||.....    |...||:|.:::..|
Zfish   968 LISELKRR-----------QMSPLVREGKDGAIEDIITDLRNQPYIRADGGRRSAKWKPAQQLAV 1021

  Fly  1429  1428
            Zfish  1022  1021

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:461886	63/253 (25%)
		Drf_FH3	551..737	CDD:461885	39/186 (21%)
		Smc	<765..>875	CDD:440809	25/109 (23%)
		FH2	950..1328	CDD:396655	119/389 (31%)
fmnl1b	NP_001429487.1	None