Protein Alignment DAAM and fmn1

DIOPT Version :10

• Sequence 1: NP_001188522.1
• Gene: DAAM / 31075
• FlyBaseID: FBgn0025641
• Length: 1463
• Species: Drosophila melanogaster
• Sequence 2: XP_031746097.1
• Gene: fmn1 / 100170173
• XenbaseID: XB-GENE-940125
• Length: 1423
• Species: Xenopus tropicalis
• Alignment Length: 1082
• Identity: 237/1082 - (21%)
• Similarity: 408/1082 - (37%)
• Gaps: 303/1082 - (28%)

  Fly   517 HPTAIDTIARSLAADNIRTKIAALEILGAVCLVPGGHRKVLQAMLHFQVFATERTRFQSIVNDLD 581
            |.|..::..::.:..:|:|..|.|:.: :.|:     :||:.. .::|....|..|.::|...:|
 Frog   299 HCTEHESNEQASSGRSIKTVTAKLQDI-STCV-----QKVVHT-YNYQEDGAEERRCENITELID 356

  Fly   582 RSTYAYRDNVNLKTALMSFVNAVLNYGPGQENLEFRL--------HLRYEFLMLGIQPV-----I 633
            .           :...:|.::..:.|.|.|.::|.:|        |.|.|.....|:|:     :
 Frog   357 E-----------QKEFVSQIDVPMMYEPLQCHIEKQLYGGVYNDRHGRLETCNNNIEPLPSCEYV 410

  Fly   634 DK--LRTHENETLDRHLDFF--EMVRAEDEKEFARRFKEE---------HV-------------- 671
            :|  ||..::|::| ..:::  :|.|..::..:..:..|:         ||
 Frog   411 NKNLLRVVKSESMD-ETEYWLGQMDRRGEKCSYGLKLPEKLSKSQESLNHVTVPHSAHIKLQDKP 474

  Fly   672 --------DTKSAGSMFELLRRKLS--HSPAYPHMLSLLQHMLLLP-YTGH-------C-TEHW- 716
                    ||.|...:...:.:.:|  .||...|:.|...|..:|| .|.|       | .|||
 Frog   475 TAVKTPTFDTASIMHIPCTMCKGISPVSSPVSTHLSSPQPHHRILPLQTQHVEEDLKLCGVEHWS 539

  Fly   717 -------------------------------LLIDRVVQQI-----VLQVEQRP----------- 734
                                           .|.|..:|.:     .||....|
 Frog   540 ALPDIFREPSSLQELGYDFKGSTTFNMDPDNYLFDDFLQNVKGKKTTLQPNLPPPGGGEALKDVS 604

  Fly   735 ----------------------NSDLIVDPDDPEKQLKLAAE---SPVHDPDVAPLQI------- 767
                                  |...:..||.....|.|...   ||....|..|.::
 Frog   605 RGPDTSSGLQAGVSEELSSVCDNKTTVGRPDHSILHLSLEIHTDLSPSDGEDRTPGRLQAVWPPP 669

  Fly   768 ---DVAKLVRLLVKEEQLTQA-----RKRADELEREN-------FDVQ-------SRLAKKEQEL 810
               |..:.|.|...|.:...|     |:..||||...       |:|:       ::|.::.|:|
 Frog   670 KPKDEEEKVGLKYTEAEYQAAILHLKREHKDELETLKSQSEVAIFNVRGEQAVQTAKLEEEIQKL 734

  Fly   811 DLRMQEKEDLETGLAR----------------------MRERL----EKESAQHSQAV------- 842
            ...:|.|...:.|:.|                      .||..    |::.:|.:..|
 Frog   735 QADLQNKLSHQNGVKRDVCVSTEDENSPKSFRNVCIQTDRETFLKPNEEDKSQKNDPVLPKKLNI 799

  Fly   843 ----QRAQTAEMRAEDLQHRL--------------ISEQQERARLERLVTEGSIPDDQKVAG--- 886
                |...:....:::.||..              :|...:.|.....:...|||....:.|
 Frog   800 ASISQNLASPISPSDNSQHNFPLASLSVTTPPPHPLSTSSQTASSPTPLDCTSIPPPPLLPGFPS 864

  Fly   887 ------LTGCNGAVSPPPAP-----------PMLKAIPPPPPPMAPSMMPPPPPPCPGA---PPP 931
                  |.|.:....|||.|           |...::||||||:......|||||.||.   |||
 Frog   865 VPPPPPLPGSSSVPPPPPLPGISSAPPPPPLPGFSSVPPPPPPLPDLSSVPPPPPFPGGGPPPPP 929

  Fly   932 PPSMAQTMAPAPPKVDL-----------PKKNVPQPTNPLKSFNWSK--LPDAKLQGTVWSELDE 983
            ||......:..||.:.|           |:|...:|..|:|...|::  |.:.....|:|..|.|
 Frog   930 PPFPGYGSSAVPPPLPLPLPGLFFGLSKPRKAPVEPGCPMKPLYWTRIQLKNGSSSNTLWENLKE 994

  Fly   984 SKLYNNMELESIDKLFSAYQKNGVSATDGSYEDLRVTGKAAKQK-VLSVIDGRRAQNCTILLSKL 1047
            ..:.:..|.|.:....:..||.  .....|||      |.||.| |:.::||:|:|...||:|.|
 Frog   995 PNIADTKEFEDLFAKATVQQKK--KPLSDSYE------KRAKAKQVIKLLDGKRSQAVGILISSL 1051

  Fly  1048 KMSDMEISKAILSMDSNEQLQLDMVEQLLKFTPSAEERALLDEH-----SEDIESLARADRFLYE 1107
            .:...:|.:|||::| |..:.::.:|.|.:.....||..::.:|     :||::.|.:.::||||
 Frog  1052 HLDMKDIQQAILNVD-NSVVDIETLEALYENRAQKEEMEIIKKHYQTSKAEDVKLLDKPEQFLYE 1115

  Fly  1108 ISKIPHYEQRLKSLHYKKRFMLTINDLVPRITSVMEASREVARSRRLRKLLELVLALGNYMNRG- 1171
            :|:||::.:|.:.:.::..|:..|:.:..::..:..|...:.....:|.::.|:||.|||||.|
 Frog  1116 LSQIPNFVERSQCIIFQSVFLEGISSVRRKVDIISRACDCLLERVSVRDIIGLILAFGNYMNGGN 1180

  Fly  1172 -ARGNASGFRLASLNRLADTKSSAAKGTTLLHYLVQVIERKF-------KDLLKLEDDIPHVRE- 1227
             .||.|.||.|..|.:|.|.||...| .:|:.|:|:...|.|       |.:..|    |..::
 Frog  1181 RTRGQADGFGLEILPKLKDVKSRDNK-ASLVDYVVRYYLRYFDQDAGTDKSVFPL----PESQDL 1240

  Fly  1228 --ASKVSLGEMDKDIQMLRTGLADVAREIEFHRSSGPAQQGDRFLPVMREFHAQASVRFAELEDK 1290
              ||:|...::|||::.|:..:....::::......|.:....|...|..|..:|...:...|.|
 Frog  1241 LLASQVKFEDLDKDLRKLKKDIEVCEKQLKAVVKDSPKENIQPFKDKMSSFLNKAKEEYKTEESK 1305

  Fly  1291 FQDMKTRFDRAVRLFG----EDGSVLQPDEFFGIFDSFLAAF 1328
            ....:.||:..:..||    .:...:.|:.||.::..|...|
 Frog  1306 LTRSQNRFEETIGYFGCKPKGNDKEITPNSFFVLWYEFCGDF 1347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAAM	NP_001188522.1	Drf_GBD	349..548	CDD:461886	6/30 (20%)
		Drf_FH3	551..737	CDD:461885	52/314 (17%)
		Smc	<765..>875	CDD:440809	29/189 (15%)
		FH2	950..1328	CDD:396655	107/401 (27%)
fmn1	XP_031746097.1	FH2	959..1348	CDD:396655	108/403 (27%)